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In medical applications, weakly supervised anomaly detection methods are of great interest, as only image-level annotations are required for training. Current anomaly detection methods mainly rely on generative adversarial networks or…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Julia Wolleb , Florentin Bieder , Robin Sandkühler , Philippe C. Cattin

Deep image prior (DIP) has been successfully applied to positron emission tomography (PET) image restoration, enabling represent implicit prior using only convolutional neural network architecture without training dataset, whereas the…

Medical Physics · Physics 2024-04-23 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Keisuke Matsubara , Masanobu Ibaraki

X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…

Medical Physics · Physics 2018-10-30 Guoyang Ma , Chenyang Shen , Xun Jia

Recovering a high-quality image from noisy indirect measurements is an important problem with many applications. For such inverse problems, supervised deep convolutional neural network (CNN)-based denoising methods have shown strong…

Image and Video Processing · Electrical Eng. & Systems 2020-09-16 Allard A. Hendriksen , Daniel M. Pelt , K. Joost Batenburg

Most of the Deep Neural Networks (DNNs) based CT image denoising literature shows that DNNs outperform traditional iterative methods in terms of metrics such as the RMSE, the PSNR and the SSIM. In many instances, using the same metrics, the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Prabhat KC , Rongping Zeng , M. Mehdi Farhangi , Kyle J. Myers

Training deep neural networks has become a common approach for addressing image restoration problems. An alternative for training a "task-specific" network for each observation model is to use pretrained deep denoisers for imposing only the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Tomer Garber , Tom Tirer

The explosive rise of the use of Computer tomography (CT) imaging in medical practice has heightened public concern over the patient's associated radiation dose. However, reducing the radiation dose leads to increased noise and artifacts,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Sutanu Bera , Prabir Kumar Biswas

Deep neural networks have been extensively applied in the medical domain for various tasks, including image classification, segmentation, and landmark detection. However, their application is often hindered by data scarcity, both in terms…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Roberto Di Via , Francesca Odone , Vito Paolo Pastore

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Hyungjin Chung , Eun Sun Lee , Jong Chul Ye

Diffusion models have emerged as powerful priors for image editing tasks such as inpainting and local modification, where the objective is to generate realistic content that remains consistent with observed regions. In particular, zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2026-04-30 Badr Moufad , Navid Bagheri Shouraki , Alain Oliviero Durmus , Thomas Hirtz , Eric Moulines , Jimmy Olsson , Yazid Janati

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Large denoising diffusion models, such as Stable Diffusion, have been trained on billions of image-caption pairs to perform text-conditioned image generation. As a byproduct of this training, these models have acquired general knowledge…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Alexandros Graikos , Nebojsa Jojic , Dimitris Samaras

Reducing the radiation dose in computed tomography (CT) is important to mitigate radiation-induced risks. One option is to employ a well-trained model to compensate for incomplete information and map sparse-view measurements to the CT…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Xiaoyue Li , Kai Shang , Gaoang Wang , Mark D. Butala

Self-supervised learning has been increasingly investigated for low-dose computed tomography (LDCT) image denoising, as it alleviates the dependence on paired normal-dose CT (NDCT) data, which are often difficult to collect. However, many…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Yichao Liu , Zongru Shao , Yueyang Teng , Junwen Guo

This paper proposes a deep learning-based denoising method for noisy low-dose computerized tomography (CT) images in the absence of paired training data. The proposed method uses a fidelity-embedded generative adversarial network (GAN) to…

Computer Vision and Pattern Recognition · Computer Science 2019-08-13 Hyoung Suk Park , Jineon Baek , Sun Kyoung You , Jae Kyu Choi , Jin Keun Seo

Low-dose computed tomography (CT) denoising algorithms aim to enable reduced patient dose in routine CT acquisitions while maintaining high image quality. Recently, deep learning~(DL)-based methods were introduced, outperforming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-21 Fabian Wagner , Mareike Thies , Felix Denzinger , Mingxuan Gu , Mayank Patwari , Stefan Ploner , Noah Maul , Laura Pfaff , Yixing Huang , Andreas Maier

Low-dose Positron Emission Tomography (PET) imaging presents a significant challenge due to increased noise and reduced image quality, which can compromise its diagnostic accuracy and clinical utility. Denoising diffusion probabilistic…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Boxiao Yu , Savas Ozdemir , Jiong Wu , Yizhou Chen , Ruogu Fang , Kuangyu Shi , Kuang Gong

Low-dose computed tomography (LDCT) is critical for minimizing radiation exposure, but it often leads to increased noise and reduced image quality. Traditional denoising methods, such as iterative optimization or supervised learning, often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Debopom Sutradhar , Ripon Kumar Debnath , Mohaimenul Azam Khan Raiaan , Yan Zhang , Reem E. Mohamed , Sami Azam

Deep-learning methods have shown promising performance for low-dose computed tomography (LDCT) reconstruction. However, supervised methods face the problem of lacking labeled data in clinical scenarios, and the CNN-based unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Ran An , Ke Chen , Hongwei Li