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The recent growth in data volumes produced by modern electron microscopes requires rapid, scalable, and flexible approaches to image segmentation and analysis. Few-shot machine learning, which can richly classify images from a handful of…

Reinforcement learning and planning methods require an objective or reward function that encodes the desired behavior. Yet, in practice, there is a wide range of scenarios where an objective is difficult to provide programmatically, such as…

Machine Learning · Computer Science 2018-10-02 Annie Xie , Avi Singh , Sergey Levine , Chelsea Finn

Few-shot learning refers to understanding new concepts from only a few examples. We propose an information retrieval-inspired approach for this problem that is motivated by the increased importance of maximally leveraging all the available…

Machine Learning · Computer Science 2017-11-15 Eleni Triantafillou , Richard Zemel , Raquel Urtasun

Cross-Domain Few-Shot Segmentation aims to segment categories in data-scarce domains conditioned on a few exemplars. Typical methods first establish few-shot capability in a large-scale source domain and then adapt it to target domains.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Jiahao Nie , Guanqiao Fu , Wenbin An , Yap-Peng Tan , Alex C. Kot , Shijian Lu

The protein dynamics are common and important for their biological functions and properties, the study of which usually involves time-consuming molecular dynamics (MD) simulations in silico. Recently, generative models has been leveraged as…

Biomolecules · Quantitative Biology 2024-03-13 Jiarui Lu , Zuobai Zhang , Bozitao Zhong , Chence Shi , Jian Tang

Popular approaches for few-shot classification consist of first learning a generic data representation based on a large annotated dataset, before adapting the representation to new classes given only a few labeled samples. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Nikita Dvornik , Cordelia Schmid , Julien Mairal

Few-shot classification consists of a training phase where a model is learned on a relatively large dataset and an adaptation phase where the learned model is adapted to previously-unseen tasks with limited labeled samples. In this paper,…

Machine Learning · Computer Science 2023-06-02 Xu Luo , Hao Wu , Ji Zhang , Lianli Gao , Jing Xu , Jingkuan Song

We study few-shot learning in natural language domains. Compared to many existing works that apply either metric-based or optimization-based meta-learning to image domain with low inter-task variance, we consider a more realistic setting,…

Computation and Language · Computer Science 2018-05-22 Mo Yu , Xiaoxiao Guo , Jinfeng Yi , Shiyu Chang , Saloni Potdar , Yu Cheng , Gerald Tesauro , Haoyu Wang , Bowen Zhou

In this paper, we look at the problem of cross-domain few-shot classification that aims to learn a classifier from previously unseen classes and domains with few labeled samples. Recent approaches broadly solve this problem by…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Wei-Hong Li , Xialei Liu , Hakan Bilen

Few-shot classification aims to learn a classifier to recognize unseen classes during training, where the learned model can easily become over-fitted based on the biased distribution formed by only a few training examples. A recent solution…

Machine Learning · Computer Science 2022-10-11 Dandan Guo , Long Tian , He Zhao , Mingyuan Zhou , Hongyuan Zha

The capability of accurate prediction of protein functions and properties is essential in the biotechnology industry, e.g. drug development and artificial protein synthesis, etc. The main challenges of protein function prediction are the…

Quantitative Methods · Quantitative Biology 2021-12-02 Wei-Cheng Tseng , Po-Han Chi , Jia-Hua Wu , Min Sun

Predicting protein properties is paramount for biological and medical advancements. Current protein engineering mutates on a typical protein, called the wild-type, to construct a family of homologous proteins and study their properties.…

Machine Learning · Computer Science 2024-06-26 Zhiqiang Zhong , Davide Mottin

Genetic fitness optimization using small populations or small population updates across generations generally suffers from randomly diverging evolutions. We propose a notion of highly probable fitness optimization through feasible…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Paul Vitanyi

Microscopy data collections are becoming larger and more frequent. Accurate and precise quantitative analysis tools like cell instance segmentation are necessary to benefit from them. This is challenging due to the variability in the data,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Ram J. Zaveri , Voke Brume , Gianfranco Doretto

Efficient sampling from constraint manifolds, and thereby generating a diverse set of solutions for feasibility problems, is a fundamental challenge. We consider the case where a problem is factored, that is, the underlying nonlinear…

Robotics · Computer Science 2021-03-30 Joaquim Ortiz-Haro , Valentin N. Hartmann , Ozgur S. Oguz , Marc Toussaint

Few-shot learning is devoted to training a model on few samples. Most of these approaches learn a model based on a pixel-level or global-level feature representation. However, using global features may lose local information, and using…

Computer Vision and Pattern Recognition · Computer Science 2021-12-07 Haoxing Chen , Huaxiong Li , Yaohui Li , Chunlin Chen

Few-shot Learning has been studied to mimic human visual capabilities and learn effective models without the need of exhaustive human annotation. Even though the idea of meta-learning for adaptation has dominated the few-shot learning…

Computer Vision and Pattern Recognition · Computer Science 2021-09-17 Jiawei Ma , Hanchen Xie , Guangxing Han , Shih-Fu Chang , Aram Galstyan , Wael Abd-Almageed

We propose an algorithmic strategy for improving the efficiency of Monte Carlo searches for the low-energy states of proteins. Our strategy is motivated by a model of how proteins alter their shapes. In our model when proteins fold under…

Soft Condensed Matter · Physics 2009-11-07 Michael Cahill , Sean Cahill , Kevin Cahill

Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai

Few-shot learning deals with the fundamental and challenging problem of learning from a few annotated samples, while being able to generalize well on new tasks. The crux of few-shot learning is to extract prior knowledge from related tasks…

Machine Learning · Computer Science 2021-05-11 Yingjun Du , Haoliang Sun , Xiantong Zhen , Jun Xu , Yilong Yin , Ling Shao , Cees G. M. Snoek