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Few-shot Learning aims to learn classifiers for new classes with only a few training examples per class. Existing meta-learning or metric-learning based few-shot learning approaches are limited in handling diverse domains with various…

Machine Learning · Computer Science 2019-01-30 Yu Cheng , Mo Yu , Xiaoxiao Guo , Bowen Zhou

Machine-learning models that learn from data to predict how protein sequence encodes function are emerging as a useful protein engineering tool. However, when using these models to suggest new protein designs, one must deal with the vast…

Quantitative Methods · Quantitative Biology 2021-07-07 Brian L. Hie , Kevin K. Yang

Few-shot learning is a rapidly evolving area of research in machine learning where the goal is to classify unlabeled data with only one or "a few" labeled exemplary samples. Neural networks are typically trained to minimize a distance…

Computer Vision and Pattern Recognition · Computer Science 2022-12-09 Samuel Hess , Gregory Ditzler

Cross-domain few-shot classification induces a much more challenging problem than its in-domain counterpart due to the existence of domain shifts between the training and test tasks. In this paper, we develop a novel Adaptive Parametric…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Marzi Heidari , Abdullah Alchihabi , Qing En , Yuhong Guo

Sound event detection is to infer the event by understanding the surrounding environmental sounds. Due to the scarcity of rare sound events, it becomes challenging for the well-trained detectors which have learned too much prior knowledge.…

Sound · Computer Science 2022-05-27 Chendong Zhao , Jianzong Wang , Leilai Li , Xiaoyang Qu , Jing Xiao

The dynamic nature of proteins is crucial for determining their biological functions and properties, for which Monte Carlo (MC) and molecular dynamics (MD) simulations stand as predominant tools to study such phenomena. By utilizing…

Quantitative Methods · Quantitative Biology 2024-03-13 Jiarui Lu , Bozitao Zhong , Zuobai Zhang , Jian Tang

Directed evolution is an iterative laboratory process of designing proteins with improved function by iteratively synthesizing new protein variants and evaluating their desired property with expensive and time-consuming biochemical…

Machine Learning · Computer Science 2025-09-08 Matouš Soldát , Jiří Kléma

Few-shot learning amounts to learning representations and acquiring knowledge such that novel tasks may be solved with both supervision and data being limited. Improved performance is possible by transductive inference, where the entire…

Machine Learning · Computer Science 2023-03-29 Michalis Lazarou , Tania Stathaki , Yannis Avrithis

The goal of few-shot learning is to learn a classifier that can recognize unseen classes from limited support data with labels. A common practice for this task is to train a model on the base set first and then transfer to novel classes…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Zhiqiang Shen , Zechun Liu , Jie Qin , Marios Savvides , Kwang-Ting Cheng

Motivation: Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction…

Genomics · Quantitative Biology 2024-05-21 Jiayu Shang , Cheng Peng , Yongxin Ji , Jiaojiao Guan , Dehan Cai , Xubo Tang , Yanni Sun

Learning with few samples is a major challenge for parameter-rich models like deep networks. In contrast, people learn complex new concepts even from very few examples, suggesting that the sample complexity of learning can often be reduced.…

Machine Learning · Computer Science 2019-06-11 Roman Visotsky , Yuval Atzmon , Gal Chechik

The successful application of deep learning to many visual recognition tasks relies heavily on the availability of a large amount of labeled data which is usually expensive to obtain. The few-shot learning problem has attracted increasing…

Machine Learning · Computer Science 2020-03-11 Zhongjie Yu , Lin Chen , Zhongwei Cheng , Jiebo Luo

In this article, we consider the problem of few-shot learning for classification. We assume a network trained for base categories with a large number of training examples, and we aim to add novel categories to it that have only a few, e.g.,…

Machine Learning · Computer Science 2020-03-23 Hong-Gyu Jung , Seong-Whan Lee

Few-shot learning aims to generalize to novel classes with only a few samples with class labels. Research in few-shot learning has borrowed techniques from transfer learning, metric learning, meta-learning, and Bayesian methods. These…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Jaya Krishna Mandivarapu , Eric bunch , Glenn fung

Few-shot learning is a promising approach to molecular property prediction as supervised data is often very limited. However, many important molecular properties depend on complex molecular characteristics -- such as the various 3D…

Machine Learning · Computer Science 2023-10-10 Christopher Fifty , Joseph M. Paggi , Ehsan Amid , Jure Leskovec , Ron Dror

Systematic identification of protein function is a key problem in current biology. Most traditional methods fail to identify functionally equivalent proteins if they lack similar sequences, structural data or extensive manual annotations.…

Genomics · Quantitative Biology 2016-03-08 Dan Ofer

Most approaches in few-shot learning rely on costly annotated data related to the goal task domain during (pre-)training. Recently, unsupervised meta-learning methods have exchanged the annotation requirement for a reduction in few-shot…

Machine Learning · Computer Science 2020-06-23 Carlos Medina , Arnout Devos , Matthias Grossglauser

Protein design, a grand challenge of the day, involves optimization on a fitness landscape, and leading methods adopt a model-based approach where a model is trained on a training set (protein sequences and fitness) and proposes candidates…

Machine Learning · Computer Science 2024-07-01 Saba Ghaffari , Ehsan Saleh , Alexander G. Schwing , Yu-Xiong Wang , Martin D. Burke , Saurabh Sinha

Path sampling allows the study of rare events like chemical reactions, nucleation and protein folding via a Monte Carlo (MC) exploration in path space. Instead of configuration points, this method samples short molecular dynamics (MD)…

Chemical Physics · Physics 2023-01-25 Daniel T. Zhang , Enrico Riccardi , Titus S. van Erp

This paper tackles the problem of few-shot learning, which aims to learn new visual concepts from a few examples. A common problem setting in few-shot classification assumes random sampling strategy in acquiring data labels, which is…

Computer Vision and Pattern Recognition · Computer Science 2022-01-10 Shipeng Yan , Songyang Zhang , Xuming He