English
Related papers

Related papers: Cargo size limits and forces of cell-driven microt…

200 papers

Motile eukaryotic cells display distinct modes of migration that often occur within the same cell type. It remains unclear, however, whether transitions between the migratory modes require changes in external conditions, or whether the…

Pattern Formation and Solitons · Physics 2025-05-29 Jack M. Hughes , Cristina Martinez-Torres , Carsten Beta , Leah Edelstein-Keshet , Arik Yochelis

Motor-driven intracellular transport of organelles, vesicles, and other molecular cargo is a highly collective process. An individual cargo is often pulled by a team of transport motors, with numbers ranging from only a few to several…

Statistical Mechanics · Physics 2022-01-06 Matthew P. Leighton , David A. Sivak

Suspensions of swimming micro-organisms provide examples of coordinated active dynamics. That has stimulated the study of a phenomenological theory combining synchronization and polar order in active matter. Here, we consider another…

Soft Condensed Matter · Physics 2019-04-08 M. Leoni

Cilia and flagella are essential building blocks for biological fluid transport and locomotion at the micron scale. They often beat in synchrony and may transition between different synchronization modes in the same cell type. Here, we…

Fluid Dynamics · Physics 2018-02-14 Hanliang Guo , Lisa Fauci , Michael Shelley , Eva Kanso

Long-distance bidirectional transport of organelles depends on the motor proteins kinesin and dynein. Using quantitative data obtained from a fungal model system, we previously developed ASEP-models of bidirectional motion of motors along…

Statistical Mechanics · Physics 2012-11-22 Congping Lin , Peter Ashwin , Gero Steinberg

The fast blood stream of animals is associated with large shear stresses. Consequently, blood cells have evolved a special morphology and a specific internal architecture allowing them to maintain their integrity over several weeks. For…

Subcellular Processes · Quantitative Biology 2022-10-12 Serge Dmitrieff , Adolfo Alsina , Aastha Mathur , François Nédélec

We study transport in synthetic, bi-disperse porous structures, with arrays of microchannels interconnected by a nanoporous layer. These structures are inspired by the xylem tissue in vascular plants, in which sap water travels from the…

Soft Condensed Matter · Physics 2024-07-23 Olivier Vincent , Théo Tassin , Erik J. Huber , Abraham D. Stroock

Self-propulsion and navigation due to the sensing of environmental conditions - such as durotaxis and chemotaxis - are remarkable properties of biological cells that cannot be reproduced by single-component self-propelled particles. We…

Soft Condensed Matter · Physics 2024-06-03 Clara Abaurrea-Velasco , Thorsten Auth , Gerhard Gompper

Unicellular organisms exhibit elaborate collective behaviors in response to environmental cues. These behaviors are controlled by complex biochemical networks within individual cells and coordinated through cell-to-cell communication.…

Cell Behavior · Quantitative Biology 2015-06-24 Javad Noorbakhsh , David Schwab , Allyson Sgro , Thomas Gregor , Pankaj Mehta

In vivo, cells navigate through complex environments filled with obstacles. Recently, the term 'topotaxis' has been introduced for navigation along topographic cues such as obstacle density gradients. Experimental and mathematical efforts…

Intracellular components explore the cytoplasm via active motor-driven transport in conjunction with passive diffusion. We model the motion of organelles in narrow tubular cells using analytical techniques and numerical simulations to study…

Biological Physics · Physics 2018-04-11 Saurabh Mogre , Elena F. Koslover

The molecular photo cell, i.e., a single molecule donor-acceptor complex, beside being technologically important, is a paradigmatic example of a many-body system operating in strong non-equilibrium. The quantum transport and the…

Mesoscale and Nanoscale Physics · Physics 2020-07-06 Subhajit Sarkar , Yonatan Dubi

Microtubule-based molecular motors often work in small groups to transport cargos in cells. A key question in understanding transport (and its regulation in vivo) is to identify the sensitivity of multiple-motor-based motion to various…

Biomolecules · Quantitative Biology 2016-10-06 Jing Xu , Zhanyong Shu , Stephen J. King , Steven P. Gross

The one-dimensional crawling movement of a cell is considered in this theoretical study. Our active gel model shows that for a cell with weakly mechanosensitive adhesion complexes, as myosin contractility increases, a cell starts to move at…

Soft Condensed Matter · Physics 2023-01-05 Jen-Yu Lo , Yuan-Heng Tseng , Hsuan-Yi Chen

Many natural and industrial processes rely on constrained transport, such as proteins moving through cells, particles confined in nanocomposite materials or gels, individuals in highly dense collec- tives and vehicular traffic conditions.…

Argyrodite solid electrolytes, such as Li$_6$PS$_5$Cl, exhibit some of the highest known superionic conductivities. Yet, the mechanistic understanding of Li$^+$ transport in realistic argyrodite microstructures -- where atomic-scale…

We propose an alternative mechanism for intracellular cargo transport which results from motor induced longitudinal fluctuations of cytoskeletal microtubules (MT). The longitudinal fluctuations combined with transient cargo binding to the…

Soft Condensed Matter · Physics 2007-05-23 Igor M. Kulić , Philip C. Nelson

The conditions under which biological cells switch from a static to a motile state are fundamental to the understanding of many healthy and pathological processes. In this paper, we show that even in the presence of a fully symmetric…

Biological Physics · Physics 2024-01-12 Jocelyn Étienne , Pierre Recho

Hot carriers, inheriting excess kinetic energy from high-energy photons, underpin numerous optoelectronic applications involving non-equilibrium transport processes. Current research on hot carriers has predominantly focused on inorganic…

Living cells are soft bodies of a characteristic form, but endowed with a capacity for a steady turnover of their structures. Both of these material properties, i.e. recovery of the shape after an external stress has been imposed and…

Soft Condensed Matter · Physics 2007-05-23 Erwin Frey , Klaus Kroy , Jan Wilhelm