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Few-shot learning is an established topic in natural images for years, but few work is attended to histology images, which is of high clinical value since well-labeled datasets and rare abnormal samples are expensive to collect. Here, we…

Image and Video Processing · Electrical Eng. & Systems 2022-02-21 Jiawei Yang , Hanbo Chen , Jiangpeng Yan , Xiaoyu Chen , Jianhua Yao

Medical image labels are often organized by taxonomies (e.g., organ - tissue - subtype), yet standard self-supervised learning (SSL) ignores this structure. We present a hierarchy-preserving contrastive framework that makes the label tree a…

Quantitative Methods · Quantitative Biology 2025-11-07 Alif Elham Khan

Mitochondria segmentation in electron microscopy images is essential in neuroscience. However, due to the image degradation during the imaging process, the large variety of mitochondrial structures, as well as the presence of noise,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Zhili Li , Xuejin Chen , Jie Zhao , Zhiwei Xiong

Contrastive language-image Pre-training (CLIP) [13] can leverage large datasets of unlabeled Image-Text pairs, which have demonstrated impressive performance in various downstream tasks. Given that annotating medical data is time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2023-07-13 Yuhao Wang

Contrastive learning (CL) has become a powerful approach for learning representations from unlabeled images. However, existing CL methods focus predominantly on visual appearance features while neglecting topological characteristics (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Guangyu Meng , Pengfei Gu , Peixian Liang , John P. Lalor , Erin Wolf Chambers , Danny Z. Chen

For medical image segmentation, contrastive learning is the dominant practice to improve the quality of visual representations by contrasting semantically similar and dissimilar pairs of samples. This is enabled by the observation that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Chenyu You , Weicheng Dai , Yifei Min , Fenglin Liu , David A. Clifton , S Kevin Zhou , Lawrence Hamilton Staib , James S Duncan

Reviewing radiology reports in emergency departments is an essential but laborious task. Timely follow-up of patients with abnormal cases in their radiology reports may dramatically affect the patient's outcome, especially if they have been…

Computation and Language · Computer Science 2018-12-06 Hamed Hassanzadeh , Mahnoosh Kholghi , Anthony Nguyen , Kevin Chu

Supervised deep learning needs a large amount of labeled data to achieve high performance. However, in medical imaging analysis, each site may only have a limited amount of data and labels, which makes learning ineffective. Federated…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Yawen Wu , Dewen Zeng , Zhepeng Wang , Yiyu Shi , Jingtong Hu

Unsupervised learning has been a long-standing goal of machine learning and is especially important for medical image analysis, where the learning can compensate for the scarcity of labeled datasets. A promising subclass of unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Ozan Ciga , Tony Xu , Anne L. Martel

Unsupervised learning has made substantial progress over the last few years, especially by means of contrastive self-supervised learning. The dominating dataset for benchmarking self-supervised learning has been ImageNet, for which recent…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Karin Stacke , Jonas Unger , Claes Lundström , Gabriel Eilertsen

In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Y. Logan , K. Kokilepersaud , G. Kwon , G. AlRegib , C. Wykoff , H. Yu

Vast quantities of person-generated health data (wearables) are collected but the process of annotating to feed to machine learning models is impractical. This paper discusses ways in which self-supervised approaches that use contrastive…

Machine Learning · Computer Science 2021-11-16 Kevalee Shah , Dimitris Spathis , Chi Ian Tang , Cecilia Mascolo

Self-supervised contrastive learning offers a means of learning informative features from a pool of unlabeled data. In this paper, we delve into another useful approach -- providing a way of selecting a core-set that is entirely unlabeled.…

Machine Learning · Computer Science 2021-04-08 Jeongwoo Ju , Heechul Jung , Yoonju Oh , Junmo Kim

In seismic interpretation, pixel-level labels of various rock structures can be time-consuming and expensive to obtain. As a result, there oftentimes exists a non-trivial quantity of unlabeled data that is left unused simply because…

Computer Vision and Pattern Recognition · Computer Science 2022-06-17 Kiran Kokilepersaud , Mohit Prabhushankar , Ghassan AlRegib

Background: Breast ultrasound is prominently used in diagnosing breast tumors. At present, many automatic systems based on deep learning have been developed to help radiologists in diagnosis. However, training such systems remains…

Computer Vision and Pattern Recognition · Computer Science 2024-08-21 Yunxin Tang , Siyuan Tang , Jian Zhang , Hao Chen

Medical images and reports offer invaluable insights into patient health. The heterogeneity and complexity of these data hinder effective analysis. To bridge this gap, we investigate contrastive learning models for cross-domain retrieval,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Demetrio Deanda , Yuktha Priya Masupalli , Jeong Yang , Young Lee , Zechun Cao , Gongbo Liang

Recent years have seen a rapid growth of utilizing graph neural networks (GNNs) in the biomedical domain for tackling drug-related problems. However, like any other deep architectures, GNNs are data hungry. While requiring labels in real…

Biological Physics · Physics 2022-05-03 Mengying Sun , Jing Xing , Huijun Wang , Bin Chen , Jiayu Zhou

The scarcity of annotated data has sparked significant interest in unsupervised pre-training methods that leverage medical reports as auxiliary signals for medical visual representation learning. However, existing research overlooks the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Zhe Li , Laurence T. Yang , Bocheng Ren , Xin Nie , Zhangyang Gao , Cheng Tan , Stan Z. Li

Early prediction of severe clinical deterioration and remaining length of stay can enable timely intervention and better resource allocation in high-acuity settings such as the ICU. This has driven the development of machine learning models…

Machine Learning · Computer Science 2026-04-21 Zhongyuan Liang , Junhyung Jo , Hyang-Jung Lee , Sang Kyu Kim , Irene Y. Chen

This paper proposes a novel pseudo-labeling method for medical image segmentation that can perform learning on ``individual images'' to select effective pseudo-labels. We introduce Positive and Unlabeled Learning (PU learning), which uses…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Takehiro Yamane , Itaru Tsuge , Susumu Saito , Ryoma Bise