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A large number of studies have shown the existence of metabolic covalent modifications in different molecular structures, able to store biochemical information that is not encoded by the DNA. Some of these covalent mark patterns can be…

Subcellular Processes · Quantitative Biology 2015-01-12 Ildefonso M. De la Fuente

Motivated by the geometric advantages of quaternions in representing rotations and postures, we propose a quaternion-valued supervised learning Hopfield-structured neural network (QSHNN) with a fully connected structure inspired by the…

Machine Learning · Computer Science 2026-03-02 Tianwei Wang , Xinhui Ma , Wei Pang

Artificial Kuramoto oscillatory neurons were recently introduced as an alternative to threshold units. Empirical evidence suggests that oscillatory units outperform threshold units in several tasks including unsupervised object discovery…

Neurons and Cognition · Quantitative Biology 2025-05-07 Vladimir Fanaskov , Ivan Oseledets

Through a redefinition of patterns in an Hopfield-like model, we introduce and develop an approach to model discrete systems made up of many, interacting components with inner degrees of freedom. Our approach clarifies the intrinsic…

Statistical Mechanics · Physics 2015-05-19 Elena Agliari , Adriano Barra

Brains remain unrivaled in their ability to recognize and generate complex spatiotemporal patterns. While AI is able to reproduce some of these capabilities, deep learning algorithms remain largely at odds with our current understanding of…

Neurons and Cognition · Quantitative Biology 2026-03-13 Simon Brandt , Paul Haider , Walter Senn , Federico Benitez , Mihai A. Petrovici

Brain-computer interfaces surged extraordinary developments in recent years, and a significant discrepancy now exists between the abundance of available data and the limited headway made in achieving a unified theoretical framework. This…

Neural networks with recurrent asymmetric couplings are important to understand how episodic memories are encoded in the brain. Here, we integrate the experimental observation of wide synaptic integration window into our model of sequence…

Neurons and Cognition · Quantitative Biology 2023-02-10 Zijian Jiang , Ziming Chen , Tianqi Hou , Haiping Huang

The Hopfield network (HN) is a classical model of associative memory whose dynamics are closely related to the Ising spin system with 2-body interactions. Stored patterns are encoded as minima of an energy function shaped by a Hebbian…

Applied Physics · Physics 2025-09-23 Marco Cafiso , Paolo Paradisi

In this paper, we investigate stability of a class of analytic neural networks with the synaptic feedback via event-triggered rules. This model is general and include Hopfield neural network as a special case. These event-trigger rules can…

Neural and Evolutionary Computing · Computer Science 2016-11-18 Ren Zheng , Xinlei Yi , Wenlian Lu , Tianping Chen

We propose a new model of neural network. It consists of spin variables to describe the state of neurons as in the Hopfield model and new gauge variables to describe the state of synapses. The model possesses local gauge symmetry and…

Disordered Systems and Neural Networks · Physics 2016-11-23 Tetsuo Matsui

We test four fast mean field type algorithms on Hopfield networks as an inverse Ising problem. The equilibrium behavior of Hopfield networks is simulated through Glauber dynamics. In the low temperature regime, the simulated annealing…

Disordered Systems and Neural Networks · Physics 2013-05-29 Haiping Huang

We present a multi-scale differentiable brain modeling workflow utilizing BrainPy, a unique differentiable brain simulator that combines accurate brain simulation with powerful gradient-based optimization. We leverage this capability of…

Neural and Evolutionary Computing · Computer Science 2024-09-26 Chaoming Wang , Muyang Lyu , Tianqiu Zhang , Sichao He , Si Wu

Associative Memories like the famous Hopfield Networks are elegant models for describing fully recurrent neural networks whose fundamental job is to store and retrieve information. In the past few years they experienced a surge of interest…

Machine Learning · Computer Science 2025-10-06 Dmitry Krotov , Benjamin Hoover , Parikshit Ram , Bao Pham

We study a fully connected Hopfield-type associative memory network with online activity-dependent synaptic plasticity, where neural states and synaptic couplings coevolve during retrieval. Using the generating-functional formalism, we…

Disordered Systems and Neural Networks · Physics 2026-05-22 Yoshinori Hara , Yoshiyuki Kabashima

Experimental characterization of neuronal dynamics involves recording both of spontaneous activity patterns and of responses to transient and sustained inputs. While much theoretical attention has been devoted to the spontaneous activity of…

Neurons and Cognition · Quantitative Biology 2020-07-24 Jonathan Rubin , Justyna Signerska-Rynkowska , Jonathan D. Touboul

A specific type of neural network, the Restricted Boltzmann Machine (RBM), is implemented for classification and feature detection in machine learning. RBM is characterized by separate layers of visible and hidden units, which are able to…

Disordered Systems and Neural Networks · Physics 2012-01-11 Adriano Barra , Alberto Bernacchia , Enrica Santucci , Pierluigi Contucci

Recent research has established a connection between modern Hopfield networks (HNs) and transformer attention heads, with guarantees of exponential storage capacity. However, these models still face challenges scaling storage efficiently.…

Machine Learning · Computer Science 2025-04-11 Saul Santos , António Farinhas , Daniel C. McNamee , André F. T. Martins

Krotov and Hopfield (2021) proposed a biologically plausible two-layer associative memory network with memory storage capacity exponential in the number of visible neurons. However, the capacity was only linear in the number of hidden…

Neurons and Cognition · Quantitative Biology 2026-03-11 Mohadeseh Shafiei Kafraj , Dmitry Krotov , Peter E. Latham

The computational capabilities of a neural network are widely assumed to be determined by its static architecture. Here we challenge this view by establishing that a fixed neural structure can operate in fundamentally different…

Neural and Evolutionary Computing · Computer Science 2025-09-24 Xia Chen

In [7] Krotov and Hopfield suggest a generalized version of the well-known Hopfield model of associative memory. In their version they consider a polynomial interaction function and claim that this increases the storage capacity of the…

Probability · Mathematics 2017-07-03 Mete Demircigil , Judith Heusel , Matthias Löwe , Sven Upgang , Franck Vermet