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High-resolution (HR) MRI scans obtained from research-grade medical centers provide precise information about imaged tissues. However, routine clinical MRI scans are typically in low-resolution (LR) and vary greatly in contrast and spatial…

Image and Video Processing · Electrical Eng. & Systems 2023-08-25 Jueqi Wang , Jacob Levman , Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , M. Jorge Cardoso , Razvan Marinescu

We innovatively propose a flexible and consistent face alignment framework, LDDMM-Face, the key contribution of which is a deformation layer that naturally embeds facial geometry in a diffeomorphic way. Instead of predicting facial…

Computer Vision and Pattern Recognition · Computer Science 2021-08-03 Huilin Yang , Junyan Lyu , Pujin Cheng , Xiaoying Tang

In this book chapter we study the Riemannian Geometry of the density registration problem: Given two densities (not necessarily probability densities) defined on a smooth finite dimensional manifold find a diffeomorphism which transforms…

Optimization and Control · Mathematics 2018-07-24 Martin Bauer , Sarang Joshi , Klas Modin

Latent Diffusion Models (LDM), a subclass of diffusion models, mitigate the computational complexity of pixel-space diffusion by operating within a compressed latent space constructed by Variational Autoencoders (VAEs), demonstrating…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Arpan Mahara , Md Rezaul Karim Khan , Naphtali Rishe , Wenjia Wang , Seyed Masoud Sadjadi

Latent variable models are powerful tools for learning low-dimensional manifolds from high-dimensional data. However, when dealing with constrained data such as unit-norm vectors or symmetric positive-definite matrices, existing approaches…

Machine Learning · Computer Science 2025-03-10 Leonel Rozo , Miguel González-Duque , Noémie Jaquier , Søren Hauberg

Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

In this paper, we propose a predictive regression model for longitudinal images with missing data based on large deformation diffeomorphic metric mapping (LDDMM) and deep neural networks. Instead of directly predicting image scans, our…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Sharmin Pathan , Yi Hong

In this paper, we propose an implementation of both Large Deformation Diffeomorphic Metric Mapping (LDDMM) and Metamorphosis image registration using a semi-Lagrangian scheme for geodesic shooting. We propose to solve both problems as an…

Computer Vision and Pattern Recognition · Computer Science 2021-06-17 Anton François , Pietro Gori , Joan Glaunès

Nonrigid registration is vital to medical image analysis but remains challenging for diffusion MRI (dMRI) due to its high-dimensional, orientation-dependent nature. While classical methods are accurate, they are computationally demanding,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Gianfranco Cortes , Xiaoda Qu , Baba C. Vemuri

In this paper, we propose a novel large deformation diffeomorphic registration algorithm to align high angular resolution diffusion images (HARDI) characterized by orientation distribution functions (ODFs). Our proposed algorithm seeks an…

Computer Vision and Pattern Recognition · Computer Science 2011-07-26 Jia Du , Alvina Goh , Anqi Qiu

We propose to learn a low-dimensional probabilistic deformation model from data which can be used for registration and the analysis of deformations. The latent variable model maps similar deformations close to each other in an encoding…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Julian Krebs , Hervé Delingette , Boris Mailhé , Nicholas Ayache , Tommaso Mansi

Diffeomorphic deformable image registration is one of the crucial tasks in medical image analysis, which aims to find a unique transformation while preserving the topology and invertibility of the transformation. Deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Ameneh Sheikhjafari , Michelle Noga , Kumaradevan Punithakumar , Nilanjan Ray

In current biological and medical research, statistical shape modeling (SSM) provides an essential framework for the characterization of anatomy/morphology. Such analysis is often driven by the identification of a relatively small number of…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Riddhish Bhalodia , Shireen Elhabian , Ladislav Kavan , Ross Whitaker

Variational auto-encoders (VAEs) have proven to be a well suited tool for performing dimensionality reduction by extracting latent variables lying in a potentially much smaller dimensional space than the data. Their ability to capture…

Machine Learning · Statistics 2020-10-23 Clément Chadebec , Clément Mantoux , Stéphanie Allassonnière

Diffusion models (DMs) have achieved state-of-the-art results for image synthesis tasks as well as density estimation. Applied in the latent space of a powerful pretrained autoencoder (LDM), their immense computational requirements can be…

Computer Vision and Pattern Recognition · Computer Science 2022-10-21 Jeremias Traub

Deep generative models provide a systematic way to learn nonlinear data distributions, through a set of latent variables and a nonlinear "generator" function that maps latent points into the input space. The nonlinearity of the generator…

Machine Learning · Statistics 2021-12-14 Georgios Arvanitidis , Lars Kai Hansen , Søren Hauberg

Graphs are ubiquitous, and learning on graphs has become a cornerstone in artificial intelligence and data mining communities. Unlike pixel grids in images or sequential structures in language, graphs exhibit a typical non-Euclidean…

Machine Learning · Computer Science 2026-02-12 Li Sun , Qiqi Wan , Suyang Zhou , Zhenhao Huang , Philip S. Yu

Riemannian neural networks, which extend deep learning techniques to Riemannian spaces, have gained significant attention in machine learning. To better classify the manifold-valued features, researchers have started extending Euclidean…

Machine Learning · Computer Science 2024-10-03 Ziheng Chen , Yue Song , Rui Wang , Xiaojun Wu , Nicu Sebe

Deep Learning (DL) has attracted a lot of attention for its ability to reach state-of-the-art performance in many machine learning tasks. The core principle of DL methods consists in training composite architectures in an end-to-end…

Machine Learning · Computer Science 2020-11-17 Carlos Lassance , Vincent Gripon , Antonio Ortega

We propose a novel framework to learn the spatiotemporal variability in longitudinal 3D shape data sets, which contain observations of objects that evolve and deform over time. This problem is challenging since surfaces come with arbitrary…

Computer Vision and Pattern Recognition · Computer Science 2021-08-23 Hamid Laga , Marcel Padilla , Ian H. Jermyn , Sebastian Kurtek , Mohammed Bennamoun , Anuj Srivastava