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We propose a two-component mixture of a noninformative (diffuse) and an informative prior distribution, weighted through the data in such a way to prefer the first component if a prior-data conflict arises. The data-driven approach for…

Methodology · Statistics 2017-08-02 Leonardo Egidi , Francesco Pauli , Nicola Torelli

Incorporating historical information into the design and analysis of a new clinical trial has been the subject of much recent discussion. For example, in the context of clinical trials of antibiotics for drug resistant infections, where…

Methodology · Statistics 2018-06-08 Isaac Gravestock , Leonhard Held

Recently, textual information has been proved to play a positive role in recommendation systems. However, most of the existing methods only focus on representation learning of textual information in ratings, while potential selection bias…

Information Retrieval · Computer Science 2021-10-14 Jiabin Liu , Zheng Wei , Zhengpin Li , Xiaojun Mao , Jian Wang , Zhongyu Wei , Qi Zhang

Replication of scientific studies is important for assessing the credibility of their results. However, there is no consensus on how to quantify the extent to which a replication study replicates an original result. We propose a novel…

Methodology · Statistics 2026-05-19 Roberto Macrì-Demartino , Leonardo Egidi , Leonhard Held , Samuel Pawel

The integration of external data using Bayesian mixture priors has become a powerful approach in clinical trials, offering significant potential to improve trial efficiency. Despite their strengths in analytical tractability and practical…

Methodology · Statistics 2025-10-07 Shouhao Zhou , Qiuxin Gao , Chenqi Fu , Yanxun Xu

External data borrowing in clinical trial designs has increased in recent years. This is accomplished in the Bayesian framework by specifying informative prior distributions. To mitigate the impact of potential inconsistency (bias) between…

Large pre-trained language models contain societal biases and carry along these biases to downstream tasks. Current in-processing bias mitigation approaches (like adversarial training) impose debiasing by updating a model's parameters,…

Computation and Language · Computer Science 2023-06-21 Deepak Kumar , Oleg Lesota , George Zerveas , Daniel Cohen , Carsten Eickhoff , Markus Schedl , Navid Rekabsaz

In clinical trials, there often exist multiple historical studies for the same or related treatment investigated in the current trial. Incorporating historical data in the analysis of the current study is of great importance, as it can help…

Methodology · Statistics 2021-02-02 Huaqing Jin , Guosheng Yin

Segment Anything Model (SAM) demonstrates powerful zero-shot capabilities; however, its accuracy and robustness significantly decrease when applied to medical image segmentation. Existing methods address this issue through modality fusion,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yiheng Zhong , Zihong Luo , Chengzhi Liu , Feilong Tang , Zelin Peng , Ming Hu , Yingzhen Hu , Jionglong Su , Zongyuan Ge , Imran Razzak

Recent advances in cross-prompt automated essay scoring (AES) typically train models jointly on all source prompts, often requiring additional access to unlabeled target prompt essays simultaneously. However, using all sources is suboptimal…

Computation and Language · Computer Science 2025-05-27 Sanwoo Lee , Kun Liang , Yunfang Wu

In current clinical trial development, historical information is receiving more attention as it provides utility beyond sample size calculation. Meta-analytic-predictive (MAP) priors and robust MAP priors have been proposed for…

Methodology · Statistics 2022-08-03 Tianyu Zhan , Yiwang Zhou , Ziqian Geng , Yihua Gu , Jian Kang , Li Wang , Xiaohong Huang , Elizabeth H. Slate

When prompting a language model (LM), users often expect the model to adhere to a set of behavioral principles across diverse tasks, such as producing insightful content while avoiding harmful or biased language. Instilling such principles…

Computation and Language · Computer Science 2024-05-22 Jan-Philipp Fränken , Eric Zelikman , Rafael Rafailov , Kanishk Gandhi , Tobias Gerstenberg , Noah D. Goodman

Sparse additive models have attracted much attention in high-dimensional data analysis due to their flexible representation and strong interpretability. However, most existing models are limited to single-level learning under the…

Machine Learning · Computer Science 2026-04-23 Xuelin Zhang , Xinyue Liu , Lingjuan Wu , Hong Chen

Meta-analytic-predictive (MAP) priors have been proposed as a generic approach to deriving informative prior distributions, where external empirical data are processed to learn about certain parameter distributions. The use of MAP priors is…

Methodology · Statistics 2025-11-11 Christian Röver , Tim Friede

Targeting solutions over `flat' regions of the loss landscape, sharpness-aware minimization (SAM) has emerged as a powerful tool to improve generalizability of deep neural network based learning. While several SAM variants have been…

Machine Learning · Computer Science 2025-01-14 Yilang Zhang , Bingcong Li , Georgios B. Giannakis

Use of historical control data to augment a small internal control arm in a randomized control trial (RCT) can lead to significant improvement of the efficiency of the trial. It introduces the risk of potential bias, since the historical…

Methodology · Statistics 2022-10-05 Jixian Wang , Hongtao Zhang , Ram Tiwari

A key goal of environmental health research is to assess the risk posed by mixtures of pollutants. As epidemiologic studies of mixtures can be expensive to conduct, it behooves researchers to incorporate prior knowledge about mixtures into…

Methodology · Statistics 2022-04-04 Glen McGee , Ander Wilson , Brent A Coull , Thomas F Webster

Multi-modality image fusion, particularly infrared and visible, plays a crucial role in integrating diverse modalities to enhance scene understanding. Although early research prioritized visual quality, preserving fine details and adapting…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Guanyao Wu , Haoyu Liu , Hongming Fu , Yichuan Peng , Jinyuan Liu , Xin Fan , Risheng Liu

There is a growing need for pluralistic alignment methods that can steer language models towards individual attributes and preferences. One such method, Self-Supervised Alignment with Mutual Information (SAMI), uses conditional mutual…

Computation and Language · Computer Science 2025-06-06 Soham V. Govande

Mixup data augmentation approaches have been applied for various tasks of deep learning to improve the generalization ability of deep neural networks. Some existing approaches CutMix, SaliencyMix, etc. randomly replace a patch in one image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Huafeng Qin , Xin Jin , Hongyu Zhu , Hongchao Liao , Mounîm A. El-Yacoubi , Xinbo Gao
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