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Chest X-ray (CXR) imaging is one of the most widely used diagnostic modalities in clinical practice, encompassing a broad spectrum of diagnostic tasks. Recent advancements have seen the extensive application of reasoning-based multimodal…

BACKGROUND AND OBJECTIVES: The multiple chest x-ray datasets released in the last years have ground-truth labels intended for different computer vision tasks, suggesting that performance in automated chest-xray interpretation might improve…

Chest X-Ray imaging is one of the most common radiological tools for detection of various pathologies related to the chest area and lung function. In a clinical setting, automated assessment of chest radiographs has the potential of…

Machine Learning · Computer Science 2022-10-31 David Biesner , Helen Schneider , Benjamin Wulff , Ulrike Attenberger , Rafet Sifa

This study explores the use of the Dirichlet Variational Autoencoder (DirVAE) for learning disentangled latent representations of chest X-ray (CXR) images. Our working hypothesis is that distributional sparsity, as facilitated by the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 Rachael Harkness , Alejandro F Frangi , Kieran Zucker , Nishant Ravikumar

We are in the middle of a remarkable rise in the use and capability of artificial intelligence. Much of this growth has been fueled by the success of deep learning architectures: models that map from observables to outputs via multiple…

Applications · Statistics 2017-01-02 Jason Hartford , Greg Lewis , Kevin Leyton-Brown , Matt Taddy

Instrumental variables (IVs) are widely used to estimate causal effects from non-randomized data. A canonical example is a randomized trial with noncompliance, in which the randomized treatment assignment serves as an IV for the…

Methodology · Statistics 2026-02-06 Rui Wang , Ying-Qi Zhao , Oliver Dukes , Bo Zhang

Purpose: This study aimed to develop an open-source multimodal large language model (CXR-LLAVA) for interpreting chest X-ray images (CXRs), leveraging recent advances in large language models (LLMs) to potentially replicate the image…

Computation and Language · Computer Science 2024-01-17 Seowoo Lee , Jiwon Youn , Hyungjin Kim , Mansu Kim , Soon Ho Yoon

A major obstacle to the integration of deep learning models for chest x-ray interpretation into clinical settings is the lack of understanding of their failure modes. In this work, we first investigate whether there are patient subgroups…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Emma Chen , Andy Kim , Rayan Krishnan , Jin Long , Andrew Y. Ng , Pranav Rajpurkar

We propose a data collecting and annotation pipeline that extracts information from Vietnamese radiology reports to provide accurate labels for chest X-ray (CXR) images. This can benefit Vietnamese radiologists and clinicians by annotating…

Image and Video Processing · Electrical Eng. & Systems 2023-01-11 Thao T. B. Nguyen , Tam M. Vo , Thang V. Nguyen , Hieu H. Pham , Ha Q. Nguyen

Causal inference methods are gaining increasing prominence in pharmaceutical drug development in light of the recently published addendum on estimands and sensitivity analysis in clinical trials to the E9 guideline of the International…

Methodology · Statistics 2021-04-30 Jack Bowden , Bjoern Bornkamp , Ekkehard Glimm , Frank Bretz

The instrumental variable (IV) approach is commonly used to infer causal effects in the presence of unmeasured confounding. Existing methods typically aim to estimate the mean causal effects, whereas a few other methods focus on quantile…

Methodology · Statistics 2025-03-13 Anastasiia Holovchak , Sorawit Saengkyongam , Nicolai Meinshausen , Xinwei Shen

Chest radiography is a relatively cheap, widely available medical procedure that conveys key information for making diagnostic decisions. Chest X-rays are almost always used in the diagnosis of respiratory diseases such as pneumonia or the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Matej Gazda , Jakub Gazda , Jan Plavka , Peter Drotar

Concept Bottleneck Models (CBMs) in medical imaging aim to improve model interpretability by predicting intermediate clinical concepts before final diagnoses. However, most existing CBMs treat concepts as discriminative predictors of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

To develop generic and reliable approaches for diagnosing and assessing the severity of COVID-19 from chest X-rays (CXR), a large number of well-maintained COVID-19 datasets are needed. Existing severity quantification architectures require…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Bouthaina Slika , Fadi Dornaika , Hamid Merdji , Karim Hammoudi

As deep learning models increasingly find applications in critical domains such as medical imaging, the need for transparent and trustworthy decision-making becomes paramount. Many explainability methods provide insights into how these…

Computer Vision and Pattern Recognition · Computer Science 2023-11-09 Piotr Komorowski , Hubert Baniecki , Przemysław Biecek

The role of chest X-ray (CXR) imaging, due to being more cost-effective, widely available, and having a faster acquisition time compared to CT, has evolved during the COVID-19 pandemic. To improve the diagnostic performance of CXR imaging a…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Xiao Qi , David J. Foran , John L. Nosher , Ilker Hacihaliloglu

Instrumental variable methods are fundamental to causal inference when treatment assignment is confounded by unobserved variables. In this article, we develop a general nonparametric causal framework for identification and learning with…

Methodology · Statistics 2026-02-10 Shuyuan Chen , Peng Zhang , Yifan Cui

Unobserved confounding is the main obstacle to causal effect estimation from observational data. Instrumental variables (IVs) are widely used for causal effect estimation when there exist latent confounders. With the standard IV method,…

Artificial Intelligence · Computer Science 2023-12-12 Debo Cheng , Jiuyong Li , Lin Liu , Jiji Zhang , Thuc duy Le , Jixue Liu

The field of Explainable Artificial Intelligence (XAI) aims to build explainable and interpretable machine learning (or deep learning) methods without sacrificing prediction performance. Convolutional Neural Networks (CNNs) have been…

Computer Vision and Pattern Recognition · Computer Science 2021-11-23 Shaw-Hwa Lo , Yiqiao Yin

As artificial intelligence (AI) becomes increasingly central to healthcare, the demand for explainable and trustworthy models is paramount. Current report generation systems for chest X-rays (CXR) often lack mechanisms for validating…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Sayeh Gholipour Picha , Dawood Al Chanti , Alice Caplier
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