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In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…

Computation and Language · Computer Science 2026-02-06 Chaimae Abouzahir , Congbo Ma , Nizar Habash , Farah E. Shamout

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

Specialized clinical AI assistants are rapidly entering medical practice, often framed as safer or more reliable than general-purpose large language models (LLMs). Yet, unlike frontier models, these clinical tools are rarely subjected to…

Computation and Language · Computer Science 2025-12-02 Krithik Vishwanath , Mrigayu Ghosh , Anton Alyakin , Daniel Alexander Alber , Yindalon Aphinyanaphongs , Eric Karl Oermann

Automatic evaluation is an integral aspect of dialogue system research. The traditional reference-based NLG metrics are generally found to be unsuitable for dialogue assessment. Consequently, recent studies have suggested various unique,…

Computation and Language · Computer Science 2024-01-23 Chen Zhang , Luis Fernando D'Haro , Yiming Chen , Malu Zhang , Haizhou Li

Patient-clinician communication is an asymmetric-information problem: patients often do not disclose fears, misconceptions, or practical barriers unless clinicians elicit them skillfully. Effective medical dialogue therefore requires…

Computation and Language · Computer Science 2026-04-13 Yikun Han , Joey Chan , Jingyuan Chen , Mengting Ai , Simo Du , Yue Guo

Large language models, such as GPT-4 and Med-PaLM, have shown impressive performance on clinical tasks; however, they require access to compute, are closed-source, and cannot be deployed on device. Mid-size models such as BioGPT-large,…

The advancement of natural language processing (NLP) systems in healthcare hinges on language model ability to interpret the intricate information contained within clinical notes. This process often requires integrating information from…

Computation and Language · Computer Science 2024-03-12 Zhichao Yang , Avijit Mitra , Sunjae Kwon , Hong Yu

Large Language Models (LLMs) have demonstrated impressive capabilities across a range of scientific tasks including mathematics, physics, and chemistry. Despite their successes, the effectiveness of LLMs in handling complex statistical…

Computation and Language · Computer Science 2024-10-11 Yizhang Zhu , Shiyin Du , Boyan Li , Yuyu Luo , Nan Tang

The emergence of instruction-tuned large language models (LLMs) has advanced the field of dialogue systems, enabling both realistic user simulations and robust multi-turn conversational agents. However, existing research often evaluates…

Computation and Language · Computer Science 2025-07-22 Chalamalasetti Kranti , Sherzod Hakimov , David Schlangen

Large Language Models (LLMs) are pretrained on extensive multilingual corpora to acquire both language-specific cultural knowledge and general knowledge. Ideally, while LLMs should provide consistent responses to culture-independent…

Computation and Language · Computer Science 2025-02-11 Yumeng Wang , Zhiyuan Fan , Qingyun Wang , May Fung , Heng Ji

Developing artificial intelligence (AI) for clinical research requires a comprehensive data foundation that supports model training and rigorous evaluation. Here, we introduce TrialPanorama, a large-scale structured resource that aggregates…

Artificial Intelligence · Computer Science 2025-12-17 Zifeng Wang , Jiacheng Lin , Qiao Jin , Junyi Gao , Jathurshan Pradeepkumar , Pengcheng Jiang , Zhiyong Lu , Jimeng Sun

This paper describes our submission to the MEDIQA-Chat 2023 shared task for automatic clinical note generation from doctor-patient conversations. We report results for two approaches: the first fine-tunes a pre-trained language model (PLM)…

Computation and Language · Computer Science 2023-06-06 John Giorgi , Augustin Toma , Ronald Xie , Sondra S. Chen , Kevin R. An , Grace X. Zheng , Bo Wang

Knowledge graphs have emerged as a popular method for injecting up-to-date, factual knowledge into large language models (LLMs). This is typically achieved by converting the knowledge graph into text that the LLM can process in context.…

Computation and Language · Computer Science 2025-04-10 Elan Markowitz , Krupa Galiya , Greg Ver Steeg , Aram Galstyan

The rapid advancement of Artificial Intelligence has resulted in the advent of Large Language Models (LLMs) with the capacity to produce text that closely resembles human communication. These models have been seamlessly integrated into…

Machine Learning · Computer Science 2025-02-04 Zenon Lamprou , Yashar Moshfeghi

There is an increasing interest in developing LLMs for medical diagnosis to improve diagnosis efficiency. Despite their alluring technological potential, there is no unified and comprehensive evaluation criterion, leading to the inability…

Computation and Language · Computer Science 2023-08-16 Xiaoming Shi , Jie Xu , Jinru Ding , Jiali Pang , Sichen Liu , Shuqing Luo , Xingwei Peng , Lu Lu , Haihong Yang , Mingtao Hu , Tong Ruan , Shaoting Zhang

Clinical diagnosis begins with doctor-patient interaction, during which physicians iteratively gather information, determine examination and refine differential diagnosis through patients' response. This dynamic clinical-reasoning process…

Computation and Language · Computer Science 2025-12-30 Yuqi Tang , Jing Yu , Zichang Su , Kehua Feng , Zhihui Zhu , Libin Wang , Lei Liang , Qiang Zhang , Keyan Ding , Huajun Chen

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to…

Knowledge distillation typically involves transferring knowledge from a Large Language Model (LLM) to a Smaller Language Model (SLM). However, in tasks such as text matching, fine-tuned smaller models often yield more effective…

Computation and Language · Computer Science 2025-07-09 Mingzhe Li , Jing Xiang , Qishen Zhang , Kaiyang Wan , Xiuying Chen

The transition of Large Language Models (LLMs) from passive knowledge retrievers to autonomous clinical agents demands a shift in evaluation-from static accuracy to dynamic behavioral reliability. To explore this boundary in dentistry, a…

Computation and Language · Computer Science 2026-01-21 Hongyang Ma , Tiantian Gu , Huaiyuan Sun , Huilin Zhu , Yongxin Wang , Jie Li , Wubin Sun , Zeliang Lian , Yinghong Zhou , Yi Gao , Shirui Wang , Zhihui Tang