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Searching for potential active compounds in large databases is a necessary step to reduce time and costs in modern drug discovery pipelines. Such virtual screening methods seek to provide predictions that allow the search space to be…

Biomolecules · Quantitative Biology 2023-05-23 Rafael Mena-Yedra , Juana L. Redondo , Horacio Pérez-Sánchez , Pilar M. Ortigosa

This work introduces Gemma, a family of lightweight, state-of-the art open models built from the research and technology used to create Gemini models. Gemma models demonstrate strong performance across academic benchmarks for language…

Computation and Language · Computer Science 2024-04-17 Gemma Team , Thomas Mesnard , Cassidy Hardin , Robert Dadashi , Surya Bhupatiraju , Shreya Pathak , Laurent Sifre , Morgane Rivière , Mihir Sanjay Kale , Juliette Love , Pouya Tafti , Léonard Hussenot , Pier Giuseppe Sessa , Aakanksha Chowdhery , Adam Roberts , Aditya Barua , Alex Botev , Alex Castro-Ros , Ambrose Slone , Amélie Héliou , Andrea Tacchetti , Anna Bulanova , Antonia Paterson , Beth Tsai , Bobak Shahriari , Charline Le Lan , Christopher A. Choquette-Choo , Clément Crepy , Daniel Cer , Daphne Ippolito , David Reid , Elena Buchatskaya , Eric Ni , Eric Noland , Geng Yan , George Tucker , George-Christian Muraru , Grigory Rozhdestvenskiy , Henryk Michalewski , Ian Tenney , Ivan Grishchenko , Jacob Austin , James Keeling , Jane Labanowski , Jean-Baptiste Lespiau , Jeff Stanway , Jenny Brennan , Jeremy Chen , Johan Ferret , Justin Chiu , Justin Mao-Jones , Katherine Lee , Kathy Yu , Katie Millican , Lars Lowe Sjoesund , Lisa Lee , Lucas Dixon , Machel Reid , Maciej Mikuła , Mateo Wirth , Michael Sharman , Nikolai Chinaev , Nithum Thain , Olivier Bachem , Oscar Chang , Oscar Wahltinez , Paige Bailey , Paul Michel , Petko Yotov , Rahma Chaabouni , Ramona Comanescu , Reena Jana , Rohan Anil , Ross McIlroy , Ruibo Liu , Ryan Mullins , Samuel L Smith , Sebastian Borgeaud , Sertan Girgin , Sholto Douglas , Shree Pandya , Siamak Shakeri , Soham De , Ted Klimenko , Tom Hennigan , Vlad Feinberg , Wojciech Stokowiec , Yu-hui Chen , Zafarali Ahmed , Zhitao Gong , Tris Warkentin , Ludovic Peran , Minh Giang , Clément Farabet , Oriol Vinyals , Jeff Dean , Koray Kavukcuoglu , Demis Hassabis , Zoubin Ghahramani , Douglas Eck , Joelle Barral , Fernando Pereira , Eli Collins , Armand Joulin , Noah Fiedel , Evan Senter , Alek Andreev , Kathleen Kenealy

Starting from a high-level problem description in terms of partial differential equations using abstract tensor notation, the Chemora framework discretizes, optimizes, and generates complete high performance codes for a wide range of…

NEMF is a novel network-based ecosystem modelling framework. It is a flexible and easy-to-use tool for modelling ecosystems with low- to intermediate complexity. It is designed around the idea of visualizing an ecosystem through a network…

Quantitative Methods · Quantitative Biology 2021-04-13 Laurin Steidle , Inga Hense

The Gisela framework for declarative programming was developed with the specific aim of providing a tool that would be useful for knowledge representation and reasoning within real-world applications. To achieve this, a complete integration…

Software Engineering · Computer Science 2007-05-23 Goran Falkman , Olof Torgersson

We introduce Metatheory.jl: a lightweight and performant general purpose symbolics and metaprogramming framework meant to simplify the act of writing complex Julia metaprograms and to significantly enhance Julia with a native term rewriting…

Programming Languages · Computer Science 2021-04-14 Alessandro Cheli

Machine learning (ML) has demonstrated the promise for accurate and efficient property prediction of molecules and crystalline materials. To develop highly accurate ML models for chemical structure property prediction, datasets with…

The identification and use of structure property relationships lies at the heart of the chemical sciences. Quantum mechanics forms the basis for the unbiased virtual exploration of chemical compound space (CCS), imposing substantial compute…

Chemical Physics · Physics 2019-11-01 Anders S. Christensen , O. Anatole von Lilienfeld

Molecular dynamics simulations are an invaluable tool in numerous scientific fields. However, the ubiquitous classical force fields cannot describe reactive systems, and quantum molecular dynamics are too computationally demanding to treat…

Chemical Physics · Physics 2022-08-09 Xiangyun Lei , Andrew J. Medford

Understanding user interface (UI) functionality is a useful yet challenging task for both machines and people. In this paper, we investigate a machine learning approach for screen correspondence, which allows reasoning about UIs by mapping…

Human-Computer Interaction · Computer Science 2023-01-23 Jason Wu , Amanda Swearngin , Xiaoyi Zhang , Jeffrey Nichols , Jeffrey P. Bigham

Even though machine learning algorithms already play a significant role in data science, many current methods pose unrealistic assumptions on input data. The application of such methods is difficult due to incompatible data formats, or…

Machine Learning · Computer Science 2022-06-09 Simon Mandlik , Tomas Pevny

Rapid developments of AI tools are expected to offer unprecedented assistance to the research of natural science including chemistry. However, neither existing unimodal task-specific specialist models nor emerging general large multimodal…

Machine Learning · Computer Science 2025-01-03 Zihan Zhao , Bo Chen , Jingpiao Li , Lu Chen , Liyang Wen , Pengyu Wang , Zichen Zhu , Danyang Zhang , Ziping Wan , Yansi Li , Zhongyang Dai , Xin Chen , Kai Yu

Data-driven, machine learning (ML) models of atomistic interactions are often based on flexible and non-physical functions that can relate nuanced aspects of atomic arrangements into predictions of energies and forces. As a result, these…

Materials Science · Physics 2024-05-15 Bartosz Barzdajn , Christopher P. Race

In this work, we present the ChemNLP library that can be used for 1) curating open access datasets for materials and chemistry literature, developing and comparing traditional machine learning, transformers and graph neural network models…

Materials Science · Physics 2024-02-19 Kamal Choudhary , Mathew L. Kelley

Generalized sampling is a numerically stable framework for obtaining reconstructions of signals in different bases and frames from their samples. In this paper, we will introduce a carefully documented toolbox for performing generalized…

Mathematical Software · Computer Science 2016-11-24 Robert Dahl Jacobsen , Morten Nielsen , Morten Grud Rasmussen

With the emerging trend of GPT models, we have established a framework called AutoML-GPT that integrates a comprehensive set of tools and libraries. This framework grants users access to a wide range of data preprocessing techniques,…

Machine Learning · Computer Science 2023-09-06 Yun-Da Tsai , Yu-Che Tsai , Bo-Wei Huang , Chun-Pai Yang , Shou-De Lin

Can AI autonomously design mechanisms for computer systems on par with the creativity and reasoning of human experts? We present Glia, an AI architecture for networked systems design that uses large language models (LLMs) in a…

We present a perspective on molecular machine learning (ML) in the field of chemical process engineering. Recently, molecular ML has demonstrated great potential in (i) providing highly accurate predictions for properties of pure components…

Chemical Physics · Physics 2025-09-01 Jan G. Rittig , Manuel Dahmen , Martin Grohe , Philippe Schwaller , Alexander Mitsos

Combustion kinetic modeling is an integral part of combustion simulation, and extensive studies have been devoted to developing both high fidelity and computationally affordable models. Despite these efforts, modeling combustion kinetics is…

Feature attribution methods, such as SHAP and LIME, explain machine learning model predictions by quantifying the influence of each input component. When applying feature attributions to explain language models, a basic question is defining…

Human-Computer Interaction · Computer Science 2025-09-26 Alan Boyle , Furui Cheng , Vilém Zouhar , Mennatallah El-Assady