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The use of large language models in medical dialogue generation has garnered significant attention, with a focus on improving response quality and fluency. While previous studies have made progress in optimizing model performance for…

Computation and Language · Computer Science 2024-08-06 Chengfeng Dou , Zhi Jin , Wenpin Jiao , Haiyan Zhao , Yongqiang Zhao , Zhenwei Tao

Large Language Models (LLMs) have shown impressive capabilities in generating human-like responses. However, their lack of domain-specific knowledge limits their applicability in healthcare settings, where contextual and comprehensive…

Computation and Language · Computer Science 2024-03-14 Subash Neupane , Shaswata Mitra , Sudip Mittal , Noorbakhsh Amiri Golilarz , Shahram Rahimi , Amin Amirlatifi

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Pre-trained language models (PLM) have marked a huge leap in neural dialogue modeling. While PLMs are pre-trained on large-scale text corpora, they are usually fine-tuned on scarce dialogue data with specific domain knowledge and dialogue…

Computation and Language · Computer Science 2021-12-14 Xiaodong Gu , Kang Min Yoo , Sang-Woo Lee

Patient matching is the process of linking patients to appropriate clinical trials by accurately identifying and matching their medical records with trial eligibility criteria. We propose LLM-Match, a novel framework for patient matching…

Computation and Language · Computer Science 2025-03-26 Xiaodi Li , Shaika Chowdhury , Chung Il Wi , Maria Vassilaki , Xiaoke Liu , Terence T Sio , Owen Garrick , Young J Juhn , James R Cerhan , Cui Tao , Nansu Zong

Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho

The rapid development of large language models (LLMs) has transformed many industries, including healthcare. However, previous medical LLMs have largely focused on leveraging general medical knowledge to provide responses, without…

Computation and Language · Computer Science 2024-12-23 Ruize Shi , Hong Huang , Wei Zhou , Kehan Yin , Kai Zhao , Yun Zhao

Objectives: While Large Language Models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the…

Computation and Language · Computer Science 2025-05-01 Sichang Tu , Abigail Powers , Stephen Doogan , Jinho D. Choi

Mental health disorders impose a substantial global socioeconomic burden. While large language models (LLMs) offer 24/7, non-judgmental interactions to address this gap, pretrained models lack contextual coherence and emotional alignment…

Computation and Language · Computer Science 2026-02-17 Eric Hua Qing Zhang , Julia Ive

Medical dialogue systems (MDS) have emerged as crucial online platforms for enabling multi-turn, context-aware conversations with patients. However, existing MDS often struggle to (1) identify relevant medical knowledge and (2) generate…

Computation and Language · Computer Science 2025-06-13 Hongda Sun , Jiaren Peng , Wenzhong Yang , Liang He , Bo Du , Rui Yan

Proactive dialogues serve as a practical yet challenging dialogue problem in the era of large language models (LLMs), where the dialogue policy planning is the key to improving the proactivity of LLMs. Most existing studies enable the…

Computation and Language · Computer Science 2024-03-12 Yang Deng , Wenxuan Zhang , Wai Lam , See-Kiong Ng , Tat-Seng Chua

Large Language Models (LLMs) excel in handling general knowledge tasks, yet they struggle with user-specific personalization, such as understanding individual emotions, writing styles, and preferences. Personalized Large Language Models…

Artificial Intelligence · Computer Science 2025-09-23 Jiahong Liu , Zexuan Qiu , Zhongyang Li , Quanyu Dai , Wenhao Yu , Jieming Zhu , Minda Hu , Menglin Yang , Tat-Seng Chua , Irwin King

Recently, Large Language Models (LLMs) have showcased remarkable capabilities in natural language understanding. While demonstrating proficiency in everyday conversations and question-answering situations, these models frequently struggle…

Computation and Language · Computer Science 2023-08-28 Chaoyi Wu , Weixiong Lin , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

Computation and Language · Computer Science 2024-09-25 Zhiyuan Wang , Fangxu Yuan , Virginia LeBaron , Tabor Flickinger , Laura E. Barnes

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

We explore the potential of Large Language Models (LLMs) to assist and potentially correct physicians in medical decision-making tasks. We evaluate several LLMs, including Meditron, Llama2, and Mistral, to analyze the ability of these…

Computation and Language · Computer Science 2024-05-07 Burcu Sayin , Pasquale Minervini , Jacopo Staiano , Andrea Passerini

Large transformer-based language models (LMs) trained on huge text corpora have shown unparalleled generation capabilities. However, controlling attributes of the generated language (e.g. switching topic or sentiment) is difficult without…

Computation and Language · Computer Science 2020-03-04 Sumanth Dathathri , Andrea Madotto , Janice Lan , Jane Hung , Eric Frank , Piero Molino , Jason Yosinski , Rosanne Liu

Psychological consultation is essential for improving mental health and well-being, yet challenges such as the shortage of qualified professionals and scalability issues limit its accessibility. To address these challenges, we explore the…

Computation and Language · Computer Science 2024-08-30 Rafael Souza , Jia-Hao Lim , Alexander Davis
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