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Fundus photography has been routinely used to document the presence and severity of various retinal degenerative diseases such as age-related macula degeneration, glaucoma, and diabetic retinopathy, for which the fovea, optic disc (OD), and…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Huaqing He , Li Lin , Zhiyuan Cai , Xiaoying Tang

Clinically, the accurate annotation of lesions/tissues can significantly facilitate the disease diagnosis. For example, the segmentation of optic disc/cup (OD/OC) on fundus image would facilitate the glaucoma diagnosis, the segmentation of…

Computer Vision and Pattern Recognition · Computer Science 2022-06-23 Junde Wu , Huihui Fang , Fangxin Shang , Dalu Yang , Zhaowei Wang , Jing Gao , Yehui Yang , Yanwu Xu

Purpose: This study introduces the first adaptation of RETFound for joint optic disc (OD) and optic cup (OC) segmentation. RETFound is a well-known foundation model developed for fundus camera and optical coherence tomography images, which…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Zhenyi Zhao , Muthu Rama Krishnan Mookiah , Emanuele Trucco

Optic nerve head (ONH) detection has been a crucial area of study in ophthalmology for years. However, the significant discrepancy between fundus image datasets, each generated using a single type of fundus camera, poses challenges to the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Jiayi Wang , Yi-An Mao , Xiaoyu Ma , Sicen Guo , Yuting Shao , Xiao Lv , Wenting Han , Mark Christopher , Linda M. Zangwill , Yanlong Bi , Rui Fan

Automated Computer Aided diagnostic tools can be used for the early detection of glaucoma to prevent irreversible vision loss. In this work, we present a Multi-task Convolutional Neural Network (CNN) that jointly segments the Optic Disc…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Arunava Chakravarty , Jayanthi Sivswamy

Automated optic disc (OD) and optic cup (OC) segmentation in fundus images is relevant to efficiently measure the vertical cup-to-disc ratio (vCDR), a biomarker commonly used in ophthalmology to determine the degree of glaucomatous optic…

The Segment Anything Model (SAM) has gained popularity as a versatile image segmentation method, thanks to its strong generalization capabilities across various domains. However, when applied to optic disc (OD) and optic cup (OC)…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Jinchen Yu , Yongwei Nie , Fei Qi , Wenxiong Liao , Hongmin Cai

Fundus photography and Optical Coherence Tomography Angiography (OCT-A) are two commonly used modalities in ophthalmic imaging. With the development of deep learning algorithms, fundus image processing, especially retinal vessel…

Image and Video Processing · Electrical Eng. & Systems 2019-11-07 Weilin Fu , Lennart Husvogt , Stefan Ploner James G. Fujimoto Andreas Maier

Purpose: The integration of multimodal imaging into operating rooms paves the way for comprehensive surgical scene understanding. In ophthalmic surgery, by now, two complementary imaging modalities are available: operating microscope (OPMI)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Nikolo Rohrmoser , Ghazal Ghazaei , Michael Sommersperger , Nassir Navab

Existing multi-modal learning methods on fundus and OCT images mostly require both modalities to be available and strictly paired for training and testing, which appears less practical in clinical scenarios. To expand the scope of clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Lehan Wang , Chongchong Qi , Chubin Ou , Lin An , Mei Jin , Xiangbin Kong , Xiaomeng Li

Purpose: Automatic and accurate segmentation of fundus vessel images has become an essential prerequisite for computer-aided diagnosis of ophthalmic diseases such as diabetes mellitus. The task of high-precision retinal vessel segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Xiang Li , Mingsi Liu , Lixin Duan

The segmentation of optic disc(OD) and optic cup(OC) from fundus images is an important fundamental task for glaucoma diagnosis. In the clinical practice, it is often necessary to collect opinions from multiple experts to obtain the final…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Junde Wu , Huihui Fang , Fangxin Shang , Zhaowei Wang , Dalu Yang , Wenshuo Zhou , Yehui Yang , Yanwu Xu

Optical Coherence Tomography (OCT) is a novel and effective screening tool for ophthalmic examination. Since collecting OCT images is relatively more expensive than fundus photographs, existing methods use multi-modal learning to complement…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Lehan Wang , Weihang Dai , Mei Jin , Chubin Ou , Xiaomeng Li

Convolutional Neural Networks (CNNs) have shown to be powerful medical image segmentation models. In this study, we address some of the main unresolved issues regarding these models. Specifically, training of these models on small medical…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Davood Karimi , Ali Gholipour

Optic disc (OD) and optic cup (OC) are regions of prominent clinical interest in a retinal fundus image. They are the primary indicators of a glaucomatous condition. With the advent and success of deep learning for healthcare research,…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Aniketh Manjunath , Subramanya Jois , Chandra Sekhar Seelamantula

We have developed and trained a convolutional neural network to automatically and simultaneously segment optic disc, fovea and blood vessels. Fundus images were normalised before segmentation was performed to enforce consistency in…

Computer Vision and Pattern Recognition · Computer Science 2017-02-03 Jen Hong Tan , U. Rajendra Acharya , Sulatha V. Bhandary , Kuang Chua Chua , Sobha Sivaprasad

Accurate segmentation of macular edema, a hallmark pathological feature in vision-threatening conditions such as age-related macular degeneration and diabetic macular edema, is essential for clinical diagnosis and management. To overcome…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Li Yang , Yuting Liu

Retinal fundus photography offers a non-invasive way to diagnose and monitor a variety of retinal diseases, but is prone to inherent quality glitches arising from systemic imperfections or operator/patient-related factors. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Vamsi Krishna Vasa , Peijie Qiu , Wenhui Zhu , Yujian Xiong , Oana Dumitrascu , Yalin Wang

Most of the existing deep learning based methods for vessel segmentation neglect two important aspects of retinal vessels, one is the orientation information of vessels, and the other is the contextual information of the whole fundus…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Xinxu Wei , Kaifu Yang , Danilo Bzdok , Yongjie Li

Focusing on the complicated pathological features, such as blurred boundaries, severe scale differences between symptoms, background noise interference, etc., in the task of retinal edema lesions joint segmentation from OCT images and…

Image and Video Processing · Electrical Eng. & Systems 2024-01-03 Meng Wang , Kai Yu , Chun-Mei Feng , Ke Zou , Yanyu Xu , Qingquan Meng , Rick Siow Mong Goh , Yong Liu , Huazhu Fu
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