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Related papers: Facilitating Bioinformatics Reproducibility

200 papers

Rapid advances in computing technology over the past few decades have spurred two extraordinary phenomena in science: large-scale and high-throughput data collection coupled with the creation and implementation of complex statistical…

Other Statistics · Statistics 2020-07-27 Roger D. Peng , Stephanie C. Hicks

This paper introduces reproducible research, and explains its importance, benefits and challenges. Some important tools for conducting reproducible research in Transportation Research are also introduced. Moreover, the source code for…

Digital Libraries · Computer Science 2021-05-17 Zuduo Zheng

The Coq Platform is a continuously developed distribution of the Coq proof assistant together with commonly used libraries, plugins, and external tools useful in Coq-based formal verification projects. The Coq Platform enables reproducing…

Logic in Computer Science · Computer Science 2022-03-21 Karl Palmskog , Enrico Tassi , Théo Zimmermann

In the rapidly evolving fields of Artificial Intelligence (AI) and Machine Learning (ML), the reproducibility crisis underscores the urgent need for clear validation methodologies to maintain scientific integrity and encourage advancement.…

Computers and Society · Computer Science 2025-04-01 Abhyuday Desai , Mohamed Abdelhamid , Nakul R. Padalkar

The integration of machine learning techniques in materials discovery has become prominent in materials science research and has been accompanied by an increasing trend towards open-source data and tools to propel the field. Despite the…

Materials Science · Physics 2026-05-27 Daniel Persaud , Logan Ward , Jason Hattrick-Simpers

Computational reproducibility is central to scientific credibility, yet verifying published results at scale remains costly. We develop an AI-assisted workflow for automated full-paper replication -- retrieving materials, reconstructing…

Econometrics · Economics 2026-03-27 Yiqing Xu , Leo Yang Yang

Those seeking to reproduce a computational experiment often need to manually look at the code to see how to build necessary libraries, configure parameters, find data, and invoke the experiment; it is not automatic. Automatic…

Software Engineering · Computer Science 2023-07-24 Samuel Grayson , Reed Milewicz , Joshua Teves , Daniel S. Katz , Darko Marinov

A recent study showed that more than 70% of researchers fail to reproduce their peers's experiments and more than half fail to reproduce their own experiments. Obviously, from a perspective of scientific quality this is a more than…

Human-Computer Interaction · Computer Science 2021-03-18 Andrew Tristan , Vinicius Woloszyn , Ben Kaden

Reproducibility in research remains hindered by complex systems involving data, models, tools, and algorithms. Studies highlight a reproducibility crisis due to a lack of standardized reporting, code and data sharing, and rigorous…

Software Engineering · Computer Science 2024-11-05 Venkat S. Malladi , Maria Yazykova , Olesya Melnichenko , Yulia Dubinina

This document explores the advantages of integrating open source software and practices in managing a scientific lab, emphasizing reproducibility and the avoidance of pitfalls. It details practical applications from website management using…

Computers and Society · Computer Science 2024-05-14 Julien Cohen-Adad

Computational physics increasingly depends on large simulation datasets generated by software that remains under active development for many years. In such settings, reproducibility requires not only well documented data but also explicit…

Computational Physics · Physics 2026-04-30 Markus Uehlein , Tobias Held , Christopher Seibel , Lukas G. Jonda , Baerbel Rethfeld , Sebastian T. Weber

Whole Tale http://wholetale.org is a web-based, open-source platform for reproducible research supporting the creation, sharing, execution, and verification of "Tales" for the scientific research community. Tales are executable research…

Reproducibility is central to the credibility of scientific findings, yet complete replication studies are costly and infrequent. However, many biological experiments contain internal replication, which is defined as repetition across…

Applications · Statistics 2025-06-05 Stanley E. Lazic

Objective: In this study, we aim to replicate an artefact-based study on software testing to address the gap. We focus on (a) providing a step by step guide of the replication, reflecting on challenges when replicating artefact-based…

Software Engineering · Computer Science 2022-04-14 Nasir Mehmood Minhas , Mohsin Irshad , Kai Petersen , Jürgen Börstler

The rapid growth of scientific software has created practical barriers for bioinformatics research. Although powerful statistical, artificial intelligence (AI)-based methods are now widely available, their effective use is often hindered by…

Software Engineering · Computer Science 2026-04-24 Simon Süwer , Zoe Chervontseva , Kester Bagemihl , Jan Baumbach , Olga Tsoy , Andreas Maier

The challenge of replicating research results has posed a significant impediment to the field of molecular biology. The advent of modern intelligent systems has led to notable progress in various domains. Consequently, we embarked on an…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Jieming Cui , Ziren Gong , Baoxiong Jia , Siyuan Huang , Zilong Zheng , Jianzhu Ma , Yixin Zhu

Motivation: Bioinformatics is faced with a variety of problems that require human involvement. Tasks like genome annotation, image analysis, knowledge-base construction and protein structure determination all benefit from human input. In…

Quantitative Methods · Quantitative Biology 2013-07-01 Benjamin M. Good , Andrew I. Su

Context: Mining software repositories is a popular means to gain insights into a software project's evolution, monitor project health, support decisions and derive best practices. Tools supporting the mining process are commonly applied by…

Software Engineering · Computer Science 2025-11-13 Nicole Hoess , Carlos Paradis , Rick Kazman , Wolfgang Mauerer

Biology has taken strong steps towards becoming a computer science aiming at reprogramming nature after the realisation that nature herself has reprogrammed organisms by harnessing the power of natural selection and the digital prescriptive…

Neural and Evolutionary Computing · Computer Science 2016-01-21 Hector Zenil , Angelika Schmidt , Jesper Tegnér
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