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Related papers: Facilitating Bioinformatics Reproducibility

200 papers

Machine learning (ML) is an increasingly important scientific tool supporting decision making and knowledge generation in numerous fields. With this, it also becomes more and more important that the results of ML experiments are…

Machine Learning · Computer Science 2020-06-23 Sheeba Samuel , Frank Löffler , Birgitta König-Ries

In the rapidly evolving domain of next generation sequencing and bioinformatics analysis, data generation is one aspect that is increasing at a concomitant rate. The burden associated with processing large amounts of sequencing data has…

Genomics · Quantitative Biology 2015-03-11 Matthew J. Wade , Thomas P. Curtis , Russell J. Davenport

Provenance has been thought of a mechanism to verify a workflow and to provide workflow reproducibility. This provenance of scientific workflows has been effectively carried out in Grid based scientific workflow systems. However, recent…

Databases · Computer Science 2015-12-01 Khawar Hasham , Kamran Munir , Richard McClatchey

Computational reproducibility is a growing problem that has been extensively studied among computational researchers and within the signal processing and machine learning research community. However, with the changing landscape of signal…

Signal Processing · Electrical Eng. & Systems 2022-02-16 Joseph Shenouda , Waheed U. Bajwa

The field of deep learning has witnessed significant breakthroughs, spanning various applications, and fundamentally transforming current software capabilities. However, alongside these advancements, there have been increasing concerns…

Machine Learning · Computer Science 2025-05-07 Nikita Ravi , Abhinav Goel , James C. Davis , George K. Thiruvathukal

The integration of bioinformatics predictions and experimental validation plays a pivotal role in advancing biological research, from understanding molecular mechanisms to developing therapeutic strategies. Bioinformatics tools and methods…

Science is conducted collaboratively, often requiring the sharing of knowledge about computational experiments. When experiments include only datasets, they can be shared using Uniform Resource Identifiers (URIs) or Digital Object…

Databases · Computer Science 2018-06-19 Zhihao Yuan , Dai Hai Ton That , Siddhant Kothari , Gabriel Fils , Tanu Malik

Data volumes and rates of research infrastructures will continue to increase in the upcoming years and impact how we interact with their final data products. Little of the processed data can be directly investigated and most of it will be…

Instrumentation and Methods for Astrophysics · Physics 2024-04-23 Michael A. C. Johnson , Hans-Rainer Klöckner , Albina Muzafarova , Kristen Lackeos , David J. Champion , Marta Dembska , Sirko Schindler , Marcus Paradies

Reproducibility is one of the core dimensions that concur to deliver Trustworthy Artificial Intelligence. Broadly speaking, reproducibility can be defined as the possibility to reproduce the same or a similar experiment or method, thereby…

Artificial Intelligence · Computer Science 2023-02-27 Riccardo Albertoni , Sara Colantonio , Piotr Skrzypczyński , Jerzy Stefanowski

In complex data analyses it is increasingly important to capture information about the usage of data sets in addition to their preservation over time to ensure reproducibility of results, to verify the work of others and to ensure…

Software Engineering · Computer Science 2018-03-21 Richard McClatchey

Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

Results of simulation studies evaluating the performance of statistical methods are often considered actionable and thus can have a major impact on the way empirical research is implemented. However, so far there is limited evidence about…

Independent computational reproducibility of scientific results is rapidly becoming of pivotal importance in scientific progress as computation itself plays a more and more central role in so many branches of science. Historically,…

Quantitative Methods · Quantitative Biology 2016-08-25 Les Hatton , Gregory Warr

Benchmarking, which involves collecting reference datasets and demonstrating method performances, is a requirement for the development of new computational tools, but also becomes a domain of its own to achieve neutral comparisons of…

Other Quantitative Biology · Quantitative Biology 2025-07-24 Izaskun Mallona , Charlotte Soneson , Ben Carrillo , Almut Luetge , Daniel Incicau , Reto Gerber , Anthony Sonrel , Mark D. Robinson

The high incidence of irreproducible research has led to urgent appeals for transparency and equitable practices in open science. For the scientific disciplines that rely on computationally intensive analyses of large data sets, a granular…

In recent years there has been widespread concern in the scientific community over a reproducibility crisis. Among the major causes that have been identified is statistical: In many scientific research the statistical analysis (including…

Applications · Statistics 2017-08-17 Norman Matloff , Reed Davis , Laurel Beckett , Paul Thompson

Motivation: The rapid growth of biological data has intensified the need for transparent, reproducible, and well-documented computational workflows. The ability to clearly connect the steps of a workflow in the code with their description…

Computation and Language · Computer Science 2026-03-10 Clémence Sebe , Olivier Ferret , Aurélie Névéol , Mahdi Esmailoghli , Ulf Leser , Sarah Cohen-Boulakia

In the data science courses at the University of British Columbia, we define data science as the study, development and practice of reproducible and auditable processes to obtain insight from data. While reproducibility is core to our…

Computers and Society · Computer Science 2022-07-26 Joel Ostblom , Tiffany Timbers

An essential part of research and scientific communication is researchers' ability to reproduce the results of others. While there have been increasing standards for authors to make data and code available, many of these files are hard to…

Digital Libraries · Computer Science 2021-09-23 Layan Bahaidarah , Ethan Hung , Andreas F. De Melo Oliveira , Jyotsna Penumaka , Lukas Rosario , Ana Trisovic

Reproducibility is a crucial aspect of scientific research that involves the ability to independently replicate experimental results by analysing the same data or repeating the same experiment. Over the years, many works have been proposed…

Digital Libraries · Computer Science 2024-07-16 Andrea Bianchi , Giordano d'Aloisio , Francesca Marzi , Antinisca Di Marco