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In MRI, variations in scan parameters, sequence, or hardware can lead to discrepancies in image appearance, even for the same subject. These inconsistencies, known as domain shifts, can hinder image analysis and degrade the performance of…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Minjun Kim , Dong Ju Mun , Hwihun Jeong , Hangyeol Park , Haechang Lee , Se Young Chun , Jongho Lee

Blind harmonization has emerged as a promising technique for MR image harmonization to achieve scale-invariant representations, requiring only target domain data (i.e., no source domain data necessary). However, existing methods face…

Image and Video Processing · Electrical Eng. & Systems 2025-05-02 Hwihun Jeong , Hayeon Lee , Se Young Chun , Jongho Lee

Lack of standardization and various intrinsic parameters for magnetic resonance (MR) image acquisition results in heterogeneous images across different sites and devices, which adversely affects the generalization of deep neural networks.…

Magnetic resonance imaging (MRI) has greatly advanced neuroscience research and clinical diagnostics. However, imaging data collected across different scanners, acquisition protocols, or imaging sites often exhibit substantial…

Image and Video Processing · Electrical Eng. & Systems 2026-04-02 Qinqin Yang , Firoozeh Shomal-Zadeh , Ali Gholipour

For machine learning-based prognosis and diagnosis of rare diseases, such as pediatric brain tumors, it is necessary to gather medical imaging data from multiple clinical sites that may use different devices and protocols. Deep…

Image harmonization, which involves adjusting the foreground of a composite image to attain a unified visual consistency with the background, can be conceptualized as an image-to-image translation task. Diffusion models have recently…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Pengfei Zhou , Fangxiang Feng , Xiaojie Wang

Deep learning algorithms utilizing magnetic resonance (MR) images have demonstrated cutting-edge proficiency in autonomously segmenting multiple sclerosis (MS) lesions. Despite their achievements, these algorithms may struggle to extend…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Jinwei Zhang , Lianrui Zuo , Blake E. Dewey , Samuel W. Remedios , Savannah P. Hays , Dzung L. Pham , Jerry L. Prince , Aaron Carass

Conventional and deep learning-based methods have shown great potential in the medical imaging domain, as means for deriving diagnostic, prognostic, and predictive biomarkers, and by contributing to precision medicine. However, these…

Magnetic resonance imaging (MRI) is an invaluable tool for clinical and research applications. Yet, variations in scanners and acquisition parameters cause inconsistencies in image contrast, hindering data comparability and reproducibility…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Robbie Holland , Viktoria Ehm , Jan C. Peeken , Benedikt Wiestler , Daniel Rueckert

Diffusion imaging is an important method in the field of neuroscience, as it is sensitive to changes within the tissue microstructure of the human brain. However, a major challenge when using MRI to derive quantitative measures is that the…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Simon Koppers , Luke Bloy , Jeffrey I. Berman , Chantal M. W. Tax , J. Christopher Edgar , Dorit Merhof

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Harmonization improves data consistency and is central to effective integration of diverse imaging data acquired across multiple sites. Recent deep learning techniques for harmonization are predominantly supervised in nature and hence…

Image and Video Processing · Electrical Eng. & Systems 2021-10-04 Siyuan Liu , Pew-Thian Yap

In clinical practice, medical segmentation datasets are often limited and heterogeneous, with variations in modalities, protocols, and anatomical targets across institutions. Existing deep learning models struggle to jointly learn from such…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Weiwei Ma , Xiaobing Yu , Peijie Qiu , Jin Yang , Pan Xiao , Xiaoqi Zhao , Xiaofeng Liu , Tomo Miyazaki , Shinichiro Omachi , Yongsong Huang

Harmonization of T1-weighted MR images across different scanners is crucial for ensuring consistency in neuroimaging studies. This study introduces a novel approach to direct image harmonization, moving beyond feature standardization to…

Magnetic resonance (MR) imaging is commonly used in the clinical setting to non-invasively monitor the body. There exists a large variability in MR imaging due to differences in scanner hardware, software, and protocol design. Ideally, a…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Savannah P. Hays , Samuel W. Remedios , Lianrui Zuo , Ellen M. Mowry , Scott D. Newsome , Peter A. Calabresi , Aaron Carass , Blake E. Dewey , Jerry L. Prince

Accuracy and consistency are two key factors in computer-assisted magnetic resonance (MR) image analysis. However, contrast variation from site to site caused by lack of standardization in MR acquisition impedes consistent measurements. In…

Image and Video Processing · Electrical Eng. & Systems 2021-03-25 Lianrui Zuo , Blake E. Dewey , Aaron Carass , Yihao Liu , Yufan He , Peter A. Calabresi , Jerry L. Prince

Magnetic resonance (MR) images from multiple sources often show differences in image contrast related to acquisition settings or the used scanner type. For long-term studies, longitudinal comparability is essential but can be impaired by…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Alicia Durrer , Julia Wolleb , Florentin Bieder , Tim Sinnecker , Matthias Weigel , Robin Sandkühler , Cristina Granziera , Özgür Yaldizli , Philippe C. Cattin

To represent the biological variability of clinical neuroimaging populations, it is vital to be able to combine data across scanners and studies. However, different MRI scanners produce images with different characteristics, resulting in a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Nicola K Dinsdale , Mark Jenkinson , Ana IL Namburete

In this paper, we propose an unsupervised framework based on normalizing flows that harmonizes MR images to mimic the distribution of the source domain. The proposed framework consists of three steps. First, a shallow harmonizer network is…

Computer Vision and Pattern Recognition · Computer Science 2023-01-30 Farzad Beizaee , Christian Desrosiers , Gregory A. Lodygensky , Jose Dolz

Image harmonization task aims at harmonizing different composite foreground regions according to specific background image. Previous methods would rather focus on improving the reconstruction ability of the generator by some internal…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Jingtang Liang , Chi-Man Pun
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