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Modern distributed decision-making systems face significant challenges arising from data heterogeneity, dynamic environments, and the need for decentralized coordination. This paper introduces the Knowledge Sharing paradigm as an innovative…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-10 Rosario Napoli , Gabriele Morabito , Antonio Celesti , Massimo Villari , Maria Fazio

This paper presents a framework to convert argumentative texts into argument knowledge graphs (AKG). The proposed argumentative knowledge representation framework (AKReF) extends the theoretical foundation and enables the AKG to provide a…

Computation and Language · Computer Science 2025-07-17 Debarati Bhattacharjee , Ashish Anand

Processing large-scale graph datasets is computationally intensive and time-consuming. Processor-centric CPU and GPU architectures, commonly used for graph applications, often face bottlenecks caused by extensive data movement between the…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-11 Marzieh Barkhordar , Alireza Tabatabaeian , Mohammad Sadrosadati , Christina Giannoula , Juan Gomez Luna , Izzat El Hajj , Onur Mutlu , Alaa R. Alameldeen

Objective: Modern medicine needs to shift from a wait and react, curative discipline to a preventative, interdisciplinary science aiming at providing personalised, systemic and precise treatment plans to patients. The aim of this work is to…

Machine Learning · Statistics 2020-09-18 Pietro Barbiero , Ramon Viñas Torné , Pietro Lió

The neighbourhood matrix, $\mathcal{NM}(G)$, a novel representation of graphs proposed in \cite {ALPaper} is defined using the neighbourhood sets of the vertices. The matrix also exhibits a bijection between the product of two well-known…

Data Structures and Algorithms · Computer Science 2020-02-12 Sivakumar Karunakaran , Lavanya Selvaganesh

Graphs as a type of data structure have recently attracted significant attention. Representation learning of geometric graphs has achieved great success in many fields including molecular, social, and financial networks. It is natural to…

Machine Learning · Computer Science 2021-07-08 Tian Xia , Wei-Shinn Ku

Much of the recent work on learning molecular representations has been based on Graph Convolution Networks (GCN). These models rely on local aggregation operations and can therefore miss higher-order graph properties. To remedy this, we…

Machine Learning · Computer Science 2019-05-31 Benson Chen , Regina Barzilay , Tommi Jaakkola

Molecular graphs generally contain subgraphs (known as groups) that are identifiable and significant in composition, functionality, geometry, etc. Flat latent representations (node embeddings or graph embeddings) fail to represent, and…

Machine Learning · Computer Science 2019-04-05 Daniel T. Chang

Complex systems of interacting components often can be modeled by a simple graph $\mathcal{G}$ that consists of a set of $n$ nodes and a set of $m$ edges. Such a graph can be represented by an adjacency matrix $A\in\R^{n\times n}$, whose…

Physics and Society · Physics 2025-09-17 Silvia Noschese , Lothar Reichel

Finding vertex-to-vertex correspondences in real-world graphs is a challenging task with applications in a wide variety of domains. Structural matching based on graphs connectivities has attracted considerable attention, while the…

Data Structures and Algorithms · Computer Science 2024-10-01 Raphaël Candelier

Knowledge Graphs (KGs) have become increasingly common for representing large-scale linked data. However, their immense size has required graph learning systems to assist humans in analysis, interpretation, and pattern detection. While…

Artificial Intelligence · Computer Science 2024-02-12 Jeffrey Sardina , Luca Costabello , Christophe Guéret

Medical deep learning models depend heavily on domain-specific knowledge to perform well on knowledge-intensive clinical tasks. Prior work has primarily leveraged unimodal knowledge graphs, such as the Unified Medical Language System…

Artificial Intelligence · Computer Science 2025-05-26 Xiaochen Wang , Yuan Zhong , Lingwei Zhang , Lisong Dai , Ting Wang , Fenglong Ma

Molecular property prediction is of crucial importance in many disciplines such as drug discovery, molecular biology, or material and process design. The frequently employed quantitative structure-property/activity relationships…

Biomolecules · Quantitative Biology 2024-01-17 Jan G. Rittig , Qinghe Gao , Manuel Dahmen , Alexander Mitsos , Artur M. Schweidtmann

Background: Computational drug repurposing is a cost- and time-efficient approach that aims to identify new therapeutic targets or diseases (indications) of existing drugs/compounds. It is especially critical for emerging and/or orphan…

Quantitative Methods · Quantitative Biology 2023-04-26 Chunyu Ma , Zhihan Zhou , Han Liu , David Koslicki

Multiplexed immunofluorescence provides an unprecedented opportunity for studying specific cell-to-cell and cell microenvironment interactions. We employ graph neural networks to combine features obtained from tissue morphology with…

Drug repurposing is more relevant than ever due to drug development's rising costs and the need to respond to emerging diseases quickly. Knowledge graph embedding enables drug repurposing using heterogeneous data sources combined with…

Multi-scale biomedical knowledge networks are expanding with emerging experimental technologies that generates multi-scale biomedical big data. Link prediction is increasingly used especially in bipartite biomedical networks to identify…

Social and Information Networks · Computer Science 2022-02-25 Jinjiang Guo , Jie Li , Dawei Leng , Lurong Pan

We present a new unified graph-based representation of medical data, combining genetic information and medical records of patients with medical knowledge via a unique knowledge graph. This approach allows us to infer meaningful information…

Artificial Intelligence · Computer Science 2024-10-22 Davide Belluomo , Tiziana Calamoneri , Giacomo Paesani , Ivano Salvo

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Computation and Language · Computer Science 2025-02-26 Yanjun Gao , Ruizhe Li , Emma Croxford , John Caskey , Brian W Patterson , Matthew Churpek , Timothy Miller , Dmitriy Dligach , Majid Afshar

Electronic Medical Records (EMRs), while integral to modern healthcare, present challenges for clinical reasoning and diagnosis due to their complexity and information redundancy. To address this, we proposed medIKAL (Integrating Knowledge…

Computation and Language · Computer Science 2025-02-18 Mingyi Jia , Junwen Duan , Yan Song , Jianxin Wang
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