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The human brain is a complex system requiring both macroscopic and microscopic components for comprehensive understanding. However, mapping nonlinear relationships between these scales remains challenging due to technical limitations and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-28 Sooyoung Kim , Joonwoo Kwon , Junbeom Kwon , Jungyoun Janice Min , Sangyoon Bae , Yuewei Lin , Shinjae Yoo , Jiook Cha

In this paper we propose a deep learning approach for segmenting sub-cortical structures of the human brain in Magnetic Resonance (MR) image data. We draw inspiration from a state-of-the-art Fully-Convolutional Neural Network (F-CNN)…

Computer Vision and Pattern Recognition · Computer Science 2016-02-08 Mahsa Shakeri , Stavros Tsogkas , Enzo Ferrante , Sarah Lippe , Samuel Kadoury , Nikos Paragios , Iasonas Kokkinos

We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

Neurons and Cognition · Quantitative Biology 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

Understanding brain dynamics and functions critically depends on knowledge of the network connectivity among neurons. However, the complexity of brain structural connectivity, coupled with continuous modifications driven by synaptic…

Neurons and Cognition · Quantitative Biology 2025-07-04 Kai Chen , Mingzhang Wang , Songting Li , Douglas Zhou

Attention Deficit Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental condition; however, its neurobiological diagnosis remains challenging due to the lack of reliable imaging-based biomarkers, particularly anatomical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Qurat Ul Ain , Alptekin Temizel , Soyiba Jawed

Understanding how local neurophysiological patterns interact with global brain dynamics is essential for decoding human emotions from EEG signals. However, existing deep learning approaches often overlook the brain's intrinsic spatial…

Human-Computer Interaction · Computer Science 2026-01-16 Yijin Zhou , Fu Li , Yi Niu , Boxun Fu , Huaning Wang , Lijian Zhang

We propose a framework for constructing combinatorial complexes (CCs) from fMRI time series data that captures both pairwise and higher-order neural interactions through information-theoretic measures, bridging topological deep learning and…

Neurons and Cognition · Quantitative Biology 2026-01-06 Valentina Sánchez , Çiçek Güven , Koen Haak , Theodore Papamarkou , Gonzalo Nápoles , Marie Šafář Postma

Functional magnetic resonance imaging (fMRI) has become one of the most common imaging modalities for brain function analysis. Recently, graph neural networks (GNN) have been adopted for fMRI analysis with superior performance.…

Neurons and Cognition · Quantitative Biology 2022-11-02 Yue Yu , Xuan Kan , Hejie Cui , Ran Xu , Yujia Zheng , Xiangchen Song , Yanqiao Zhu , Kun Zhang , Razieh Nabi , Ying Guo , Chao Zhang , Carl Yang

Background: The hippocampus plays a crucial role in memory and cognition. Because of the associated toxicity from whole brain radiotherapy, more advanced treatment planning techniques prioritize hippocampal avoidance, which depends on an…

Medical Physics · Physics 2023-06-16 Yang Lei , Yifu Ding , Richard L. J. Qiu , Tonghe Wang , Justin Roper , Yabo Fu , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

Effective connectivity can describe the causal patterns among brain regions. These patterns have the potential to reveal the pathological mechanism and promote early diagnosis and effective drug development for cognitive disease. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Qiankun Zuo , Hao Tian , Chi-Man Pun , Hongfei Wang , Yudong Zhang , Jin Hong

Modern neuroimaging techniques, such as diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI), enable us to model the human brain as a brain network or connectome. Capturing brain networks' structural information…

Brain network analysis based on functional Magnetic Resonance Imaging (fMRI) is pivotal for diagnosing brain disorders. Existing approaches typically rely on predefined functional sub-networks to construct sub-network associations. However,…

Machine Learning · Computer Science 2026-03-11 Jingfeng Tang , Peng Cao , Guangqi Wen , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

A central question in neuroscience is how self-organizing dynamic interactions in the brain emerge on their relatively static structural backbone. Due to the complexity of spatial and temporal dependencies between different brain areas,…

Neurons and Cognition · Quantitative Biology 2020-10-15 Simon Wein , Wilhelm Malloni , Ana Maria Tomé , Sebastian M. Frank , Gina-Isabelle Henze , Stefan Wüst , Mark W. Greenlee , Elmar W. Lang

Brain network analysis plays an increasingly important role in studying brain function and the exploring of disease mechanisms. However, existing brain network construction tools have some limitations, including dependency on empirical…

Neurons and Cognition · Quantitative Biology 2024-07-29 Yongcheng Zong , Shuqiang Wang

Skull stripping magnetic resonance images (MRI) of the human brain is an important process in many image processing techniques, such as automatic segmentation of brain structures. Numerous methods have been developed to perform this task,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-16 Hjalti Thrastarson , Lotta M. Ellingsen

Precise 3D segmentation of cerebral vasculature from T1-weighted contrast-enhanced (T1CE) MRI is crucial for safe neurosurgical planning. Manual delineation is time-consuming and prone to inter-observer variability, while current automated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mohammad Jafari Vayeghan , Niloufar Delfan , Mehdi Tale Masouleh , Mansour Parvaresh Rizi , Behzad Moshiri

Convolutional neural networks (CNNs) have become increasingly difficult to deploy in resource-constrained environments due to their large memory and computational requirements. Although low-rank compression methods can reduce this burden,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Sisipho Hamlomo , Marcellin Atemkeng , Habte Tadesse Likassa , Blaise Ravelo , Thierry Bouwmans , Sébastien Lalléchère , Antoine Vacavant , Ding-Geng Chen

Functional connectivity network (FCN) data from functional magnetic resonance imaging (fMRI) is increasingly used for the diagnoses of brain disorders. However, state-of-the-art studies used to build the FCN using a single brain…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Mianxin Liu , Han Zhang , Feng Shi , Dinggang Shen