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In this paper a lattice model for diffusional transport of particles in the interphase cell nucleus is proposed. Dense networks of chromatin fibers are created by three different methods: randomly distributed, non-interconnected obstacles,…

Biological Physics · Physics 2009-11-13 Annika Wedemeier , Holger Merlitz , Chen-Xu Wu , Jörg Langowski

Nonlinear interaction of membrane proteins with cytoskeleton and membrane leads to non-Gaussian structure of their displacement probability distribution. We propose a novel statistical analysis technique for learning the characteristics of…

Biological Physics · Physics 2013-05-30 Pavel M. Lushnikov , Petr Šulc , Konstantin S. Turitsyn

In this paper, we explore the reduction of functionality in a complex system as a consequence of cumulative random damage and imperfect reparation, a phenomenon modeled as a dynamical process on networks. We analyze the global…

Statistical Mechanics · Physics 2021-06-07 L. K. Eraso-Hernandez , A. P. Riascos , T. M. Michelitsch , J. Wang-Michelitsch

Random walks on networks is the standard tool for modelling spreading processes in social and biological systems. This first-order Markov approach is used in conventional community detection, ranking, and spreading analysis although it…

Physics and Society · Physics 2014-08-13 Martin Rosvall , Alcides V. Esquivel , Andrea Lancichinetti , Jevin D. West , Renaud Lambiotte

Starting from a simple animal-biology example, a general, somewhat counter-intuitive property of diffusion random walks is presented. It is shown that for any (non-homogeneous) purely diffusing system, under any isotropic uniform incidence,…

Statistical Mechanics · Physics 2019-02-20 Stephane Blanco , Fournier Richard

The transport properties of discrete-time random walks on ring networks with deterministic shortcuts are investigated through analytical and numerical methods. The network consists of a periodic chain where each node is connected to its…

Statistical Mechanics · Physics 2026-04-30 Oscar Ivan Torres Mena , Francisco J Sevilla

In this paper we present a network model to study the impact of spatial distribution of constituents, coupling between them and diffusive processes in the context of biological situations. The model is in terms of network of mobile elements…

Molecular Networks · Quantitative Biology 2007-05-23 Kanchan Thadani , Ashutosh

Networks are a powerful tool to model the structure and dynamics of complex systems across scales. Direct connections between system components are often represented as edges, while paths and walks capture indirect interactions. This…

Physics and Society · Physics 2025-01-15 Rohit Sahasrabuddhe , Renaud Lambiotte , Martin Rosvall

Recent research has highlighted limitations of studying complex systems with time-varying topologies from the perspective of static, time-aggregated networks. Non-Markovian characteristics resulting from the ordering of interactions in…

The propagation of signalling molecules within cellular networks is affected by network topology, but also by the spatial arrangement of cells in the networks. Understanding the collective reaction--diffusion behaviour in space of signals…

Disordered Systems and Neural Networks · Physics 2025-01-09 Adel Mehrpooya , Vivien J. Challis , Pascal R. Buenzli

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

The kinesin superfamily of motor proteins is a major driver of anterograde transport of vesicles and organelles within eukaryotic cells via microtubules. Numerous studies have elucidated the step-size, velocities, forces, and navigation…

Biomolecules · Quantitative Biology 2024-10-07 Mason Grieb , Nimisha Krishnan , Jennifer L. Ross

Networks are universally considered as complex structures of interactions of large multi-component systems. In order to determine the role that each node has inside a complex network, several centrality measures have been developed. Such…

Physics and Society · Physics 2019-08-20 Malbor Asllani , Bruno Requiao da Cunha , Ernesto Estrada , James P. Gleeson

The dynamics of diffusion in complex networks are widely studied to understand how entities, such as information, diseases, or behaviors, spread in an interconnected environment. Complex networks often present community structure, and tools…

Physics and Society · Physics 2025-12-09 Alina Dubovskaya , Caroline B. Pena , David J. P. O'Sullivan

From social interactions to the human brain, higher-order networks are key to describe the underlying network geometry and topology of many complex systems. While it is well known that network structure strongly affects its function, the…

Statistical Mechanics · Physics 2022-01-11 Ana P Millán , Reza Ghorbanchian , Nicolò Defenu , Federico Battiston , Ginestra Bianconi

We consider biased random walks on random networks constituted by a random comb comprising a backbone with quenched-disordered random-length branches. The backbone and the branches run in the direction of the bias. For the bare model as…

Statistical Mechanics · Physics 2025-06-09 Mrinal Sarkar , Shamik Gupta

The amount of data that is being gathered about cities is increasing in size and specificity. However, despite this wealth of information, we still have little understanding of what really drives the processes behind urbanisation. In this…

Physics and Society · Physics 2015-11-30 Rémi Louf

Collective phenomena emerge from the interaction of natural or artificial units with a complex organization. The interplay between structural patterns and dynamics might induce functional clusters that, in general, are different from…

Physics and Society · Physics 2017-04-25 Manlio De Domenico

The problem of decomposing networks into modules (or clusters) has gained much attention in recent years, as it can account for a coarse-grained description of complex systems, often revealing functional subunits of these systems. A variety…

Mathematical Physics · Physics 2014-08-01 Natasa Djurdjevac Conrad , Ralf Banisch , Christof Schütte

We study diffusion and consensus dynamics in a Network of Networks model. In this model, there is a collection of sub-networks, connected to one another using a small number of links. We consider a setting where the links between networks…

Social and Information Networks · Computer Science 2020-02-17 Yuhao Yi , Anirban Das , Stacy Patterson , Bassam Bamieh , Zhongzhi Zhang