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Quantum annealing allows for quantum fluctuations to be used used to assist in finding the solution to some of the worlds most challenging computational problems. Recently, this field has attracted much interest because of the construction…

Quantum Physics · Physics 2022-07-26 Nicholas Chancellor

Protein folding is one of the age-old biological problems that refers to the mechanism of understanding and predicting how a protein's linear sequence of amino acids folds into its specific three dimensional structure.This structure is…

We present a number of quantum computing patterns that build on top of fundamental algorithms, that can be applied to solving concrete, NP-hard problems. In particular, we introduce the concept of a quantum dictionary as a summation of…

Quantum computer algorithms can exploit the structure of random satisfiability problems. This paper extends a previous empirical evaluation of such an algorithm and gives an approximate asymptotic analysis accounting for both the average…

Quantum Physics · Physics 2007-05-23 Tad Hogg

In recent years, quantum computing has drawn significant interest within the field of high-energy physics. We explore the potential of quantum algorithms to resolve the combinatorial problems in particle physics experiments. As a concrete…

High Energy Physics - Phenomenology · Physics 2024-11-12 Jacob L. Scott , Zhongtian Dong , Taejoon Kim , Kyoungchul Kong , Myeonghun Park

Gate model quantum computers with too many qubits to be simulated by available classical computers are about to arrive. We present a strategy for programming these devices without error correction or compilation. This means that the number…

Quantum Physics · Physics 2017-03-21 E. Farhi , J. Goldstone , S. Gutmann , H. Neven

Many problems of industrial interest are NP-complete, and quickly exhaust resources of computational devices with increasing input sizes. Quantum annealers (QA) are physical devices that aim at this class of problems by exploiting quantum…

Quantum algorithms are emerging tools in the design of functional materials due to their powerful solution space search capability. How to balance the high price of quantum computing resources and the growing computing needs has become an…

Quantum Physics · Physics 2024-05-13 Zhihao Xu , Wenjie Shang , Seongmin Kim , Alexandria Bobbitt , Eungkyu Lee , Tengfei Luo

We study the statistical mechanics of RNA secondary structures designed to have an attraction between two different types of structures as a model system for heteropolymer aggregation. The competition between the branching entropy of the…

Biological Physics · Physics 2009-11-11 Vishwesha Guttal , Ralf Bundschuh

Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide…

The recent advent of commercially available quantum annealing hardware (QAH) has expanded opportunities for research into quantum annealing-based algorithms. In the domain of power systems, this advancement has driven increased interest in…

Optimization and Control · Mathematics 2025-03-26 Rosemary Barrass , Harsha Nagarajan , Carleton Coffrin

Recent advances in DNA sequencing open prospects to make whole-genome analysis rapid and reliable, which is promising for various applications including personalized medicine. However, existing techniques for {\it de novo} genome assembly,…

Quantum Annealing (QA) is one of the most promising frameworks for quantum optimization. Here, we focus on the problem of minimizing complex classical cost functions associated with prototypical discrete neural networks, specifically the…

Quantum Physics · Physics 2023-05-17 Guglielmo Lami , Pietro Torta , Giuseppe E. Santoro , Mario Collura

The negative-AND (NAND) gate is universal for classical computation making it an important target for development. A seminal quantum computing algorithm by Farhi, Goldstone and Gutmann has demonstrated its realization by means of quantum…

Background: In the Nearest-Neighbor Thermodynamic Model, a standard approach for RNA secondary structure prediction, the energy of the multiloops is modeled using a linear entropic penalty governed by three branching parameters. Although…

Biomolecules · Quantitative Biology 2025-10-15 Svetlana Poznanović , Owen Cardwell , Christine Heitsch

The Human Genome Project has led to an exponential increase in data related to the sequence, structure, and function of biomolecules. Bioinformatics is an interdisciplinary research field that primarily uses computational methods to analyze…

Biomolecules · Quantitative Biology 2024-05-14 Yanlin Zhou , Tong Zhan , Yichao Wu , Bo Song , Chenxi Shi

As standard data loading processes, quantum state preparation and block-encoding are critical and necessary processes for quantum computing applications, including quantum machine learning, Hamiltonian simulation, and many others. Yet,…

Quantum Physics · Physics 2025-12-18 Xiao-Ming Zhang

RNA is a fundamental class of biomolecules that mediate a large variety of molecular processes within the cell. Computational algorithms can be of great help in the understanding of RNA structure-function relationship. One of the main…

Biomolecules · Quantitative Biology 2015-02-20 Sandro Bottaro , Francesco Di Palma , Giovanni Bussi

Recently developed quantum algorithms suggest that quantum computers can solve certain problems and perform certain tasks more efficiently than conventional computers. Among other reasons, this is due to the possibility of creating…

Quantum Physics · Physics 2007-05-23 Rolando D. Somma

Solving linear systems of equations is ubiquitous in all areas of science and engineering. With rapidly growing data sets, such a task can be intractable for classical computers, as the best known classical algorithms require a time…

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