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The vast majority of the microscopy methods currently available to study biological samples require staining prior to imaging. Nevertheless, the ability to reveal specific cell structures or organelles in a label-free manner remains…

Biological Physics · Physics 2020-10-06 R. Desapogu , G. Le Marchand , R. Smith , P. Ray , E. Gillier , S. Dutertre , M. Alouini , M. Tramier , S. Huet , J. Fade

Holography is a cornerstone characterisation and imaging technique that can be applied to the full electromagnetic spectrum, from X-rays to radio waves or even particles such as neutrons. The key property in all these holographic approaches…

Quantum Physics · Physics 2021-01-12 Hugo Defienne , Bienvenu Ndagano , Ashley Lyons , Daniele Faccio

Optical Coherence Tomography (OCT) was originally conceived as a volumetric imaging method. Quickly, OCT images went beyond structural data and started to provide functional information about an object enabling for example visualization of…

Photoacoustic computed tomography (PACT) is a non-invasive imaging modality, similar to ultrasound, with wide-ranging medical applications. Conventional PACT images are degraded by wavefront distortion caused by the heterogeneous speed of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Tianao Li , Manxiu Cui , Cheng Ma , Emma Alexander

Background: Cervical cancer seriously affects the health of the female reproductive system. Optical coherence tomography (OCT) emerged as a non-invasive, high-resolution imaging technology for cervical disease detection. However, OCT image…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Kaiyi Chen , Qingbin Wang , Yutao Ma

Sensing light's polarization and wavefront direction enables surface curvature assessment, material identification, shadow differentiation, and improved image quality in turbid environments. Traditional polarization cameras utilize multiple…

Direction-dependent instrumental polarisation introduces wide-field polarimetric aberrations and limits the dynamic range of low-frequency interferometric images. We therefore provide a detailed two-dimensional analysis of the Giant…

Instrumentation and Methods for Astrophysics · Physics 2014-07-03 J. S. Farnes

A prospective study was performed on neurosurgical samples from 18 patients to evaluate the use of Full-Field Optical Coherence Tomography (FF-OCT) in brain tumor diagnosis. FF-OCT captures en face slices of tissue samples at 1\mum…

We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope…

Quantum-optical coherence tomography (Q-OCT) is an interferometric technique for axial imaging offering several advantages over conventional methods. Chirped-pulse interferometry (CPI) was recently demonstrated to exhibit all of the…

Quantum Physics · Physics 2009-09-07 Jonathan Lavoie , Rainer Kaltenbaek , Kevin J. Resch

Optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO) of the eye has become essential to ophthalmology and the emerging field of oculomics, thus requiring a need for transparent, reproducible, and rapid analysis of this…

Super-resolution microscopy has catalyzed valuable insights into the sub-cellular, mechanistic details of many different biological processes across a wide range of cell types. Fluorescence polarization spectroscopy tools have also enabled…

Biological Physics · Physics 2023-01-25 Jack W Shepherd , Alex L Payne-Dwyer , Ji-Eun Lee , Aisha Syeda , Mark C Leake

Context. Phase-mask coronagraphy is advantageous in terms of inner working angle and discovery space. It is however still plagued by drawbacks such as sensitivity to tip-tilt errors and chromatism. A nulling stellar coronagraph based on the…

Instrumentation and Methods for Astrophysics · Physics 2015-06-11 P. Bourget , N. Schuhler , D. Mawet , P. Haguenauer

State-of-the-art polarimeter calibration is reviewed. Producing many quasi-random polarization states and moving/bending a fiber without changing power allows finding a polarimeter calibration where the degree-of-polarization reaches unity…

Optics · Physics 2022-07-05 Reinhold Noe , Benjamin Koch

The findings of a nine orbit calibration plan carried out during HST Cycle 15, to fully determine the NICMOS camera 2 (2.0 micron) polarization calibration to high accuracy, are reported. Recently Ueta et al. and Batcheldor et al. have…

High-resolution optical microscopy suffers from a low contrast in scattering media where a multiply scattered wave obscures a ballistic wave used for image formation. To extend the imaging depth, various gating operations - confocal,…

Optics · Physics 2018-11-08 Mooseok Jang , Hakseok Ko , Won Kyu Lee , Jae-Seung Lee , Wonshik Choi

Optical coherence tomography angiography (OCTA) is a novel and clinically promising imaging modality to image retinal and sub-retinal vasculature. Based on repeated optical coherence tomography (OCT) scans, intensity changes are observed…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Lennart Husvogt , Stefan B. Ploner , Siyu Chen , Daniel Stromer , Julia Schottenhamml , A. Yasin Alibhai , Eric Moult , Nadia K. Waheed , James G. Fujimoto , Andreas Maier

We study theoretically and experimentally coherent imaging of surface plasmon polaritons using either leakage radiation microscopy through a thin metal film or interference microscopy through a thick metal film. Using a rigorous modal…

Optical Coherence Tomography is a technique used to scan the Retina of the eye and check for tears. In this paper, we develop a Convolutional Neural Network Architecture for OCT scan classification. The model is trained to detect Retinal…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Adit Magotra , Aagat Gedam , Tanush Savadi , Emily Li

Objective: Arterial stiffness is an important marker to predict cardio vascular events. Common measurement techniques to determine the condition of the aorta are limited to the acquisition of the arterial pulse wave at the extremities. The…

Medical Physics · Physics 2019-03-06 Roman Kusche , Arthur-Vincent Lindenberg , Sebastian Hauschild , Martin Ryschka