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X-ray Computed Tomography (CT) imaging has been widely used in clinical diagnosis, non-destructive examination, and public safety inspection. Sparse-view (sparse view) CT has great potential in radiation dose reduction and scan…

Medical Physics · Physics 2019-05-29 Kaichao Liang , Hongkai Yang , Yuxiang Xing

Recovering high-dimensional statistical structure from limited measurements is a fundamental challenge in hyperspectral imaging, where capturing full-resolution data is often infeasible due to sensor, bandwidth, or acquisition constraints.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Jonathan Monsalve , Kumar Vijay Mishra

Computed tomography is widely used to examine internal structures in a non-destructive manner. To obtain high-quality reconstructions, one typically has to acquire a densely sampled trajectory to avoid angular undersampling. However, many…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Haoyu Wei , Florian Schiffers , Tobias Würfl , Daming Shen , Daniel Kim , Aggelos K. Katsaggelos , Oliver Cossairt

The high cost and low image quality traditionally associated with proton computed tomography (pCT) have prevented it from seeing significant use in clinical settings. A cheap, compact, high-density scintillating glass detector capable of…

Medical Physics · Physics 2022-06-22 Adam Zieser , Ugur Akgun , Yasar Onel

Purpose: To develop and evaluate a transformer-based deep learning model for the synthesis of nephrographic phase images in CT urography (CTU) examinations from the unenhanced and urographic phases. Materials and Methods: This retrospective…

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

Holographic coherent X-ray imaging enables nanoscale imaging of biological cells and tissues, rendering both phase and absorption contrast, i.e. real and imaginary parts of the refractive index. Unlike the standard model, which assumes a…

Analysis of PDEs · Mathematics 2026-05-29 Thorsten Hohage , Milad Karimi , Björn Müller

With the great success of diffusion models in image generation, diffusion-based image compression is attracting increasing interests. However, due to the random noise introduced in the diffusion learning, they usually produce…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Zhenyu Du , Yanbo Gao , Shuai Li , Yiyang Li , Hui Yuan , Mao Ye

In the intention of minimizing excessive X-ray radiation administration to patients, low-dose computed tomography (LDCT) has become a distinct trend in radiology. However, while lowering the radiation dose reduces the risk to the patient,…

Medical Physics · Physics 2022-04-12 Long Zhou , Xiaozhuang Wang , Min Hou , Ping Li , Chunlong Fu , Yanjun Ren , Tingting Shao , Xi Hu , Jihong Sun , Hongwei Ye

This paper proposes a spatial-Radon domain CT image reconstruction model based on data-driven tight frames (SRD-DDTF). The proposed SRD-DDTF model combines the idea of joint image and Radon domain inpainting model of \cite{Dong2013X} and…

Medical Physics · Physics 2016-01-27 Ruohan Zhan , Bin Dong

Single-shot X-ray imaging of short-lived nanostructures such as clusters and nanoparticles near a phase transition or non-crystalizing objects such as large proteins and viruses is currently the most elegant method for characterizing their…

Atomic and Molecular Clusters · Physics 2020-10-14 Thomas Stielow , Robin Schmidt , Christian Peltz , Thomas Fennel , Stefan Scheel

Computed tomography (CT) is widely used in scientific imaging systems such as synchrotron and laboratory-based nano-CT, but acquiring full-view sinograms requires high radiation dose and long scan times. Sparse-view CT reduces this burden…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Jiaze E , Srutarshi Banerjee , Tekin Bicer , Guannan Wang , Yanfu Zhang , Bin Ren

We demonstrate high-resolution non-iterative holographic coherent diffraction imaging with hard X-rays using a novel phase-shifting reference, fabricated by atomic layer deposition to produce nanosharp 3D structure. The method surpasses the…

Mesoscale and Nanoscale Physics · Physics 2016-10-17 Mirna Saliba , Jeroen Bosgra , Christoph Rau , Christian David , Aaron D. Parsons , Ulrich H. Wagner , Pierre Thibault

The restoration of images affected by blur and noise has been widely studied and has broad potential for applications including in medical imaging modalities like computed tomography (CT). Although the blur and noise in CT images can be…

Medical Physics · Physics 2024-07-23 Yijie Yuan , Grace J. Gang , J. Webster Stayman

Diffusion models have recently gained traction as a powerful class of deep generative priors, excelling in a wide range of image restoration tasks due to their exceptional ability to model data distributions. To solve image restoration…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Xiang Li , Soo Min Kwon , Shijun Liang , Ismail R. Alkhouri , Saiprasad Ravishankar , Qing Qu

Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…

Medical Physics · Physics 2024-10-28 Fumio Hashimoto , Kibo Ote

Ptychography has rapidly grown in the fields of X-ray and electron imaging for its unprecedented ability to achieve nano or atomic scale resolution while simultaneously retrieving chemical or magnetic information from a sample. A…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Mathew J. Cherukara , Tao Zhou , Youssef Nashed , Pablo Enfedaque , Alex Hexemer , Ross J. Harder , Martin V. Holt

Blur and noise corrupting Computed Tomography (CT) images can hide or distort small but important details, negatively affecting the diagnosis. In this paper, we present a novel gradient-based Plug-and-Play algorithm, constructed on the…

Numerical Analysis · Mathematics 2021-03-22 Pasquale Cascarano , Elena Loli Piccolomini , Elena Morotti , Andrea Sebastiani

Most methods tackling the phase retrieval problem of magnitude-only antenna measurements suffer from unrealistic sampling requirements, from unfeasible computational complexities, and, most severely, from the lacking reliability of…

Signal Processing · Electrical Eng. & Systems 2022-02-01 Alexander Paulus , Josef Knapp , Jonas Kornprobst , Thomas F. Eibert

Computed Tomography (CT) is a widely utilized imaging modality in clinical settings. Using densely acquired rotational X-ray arrays, CT can capture 3D spatial features. However, it is confronted with challenged such as significant time…

Image and Video Processing · Electrical Eng. & Systems 2025-07-16 Duoyou Chen , Yunqing Chen , Can Zhang , Zhou Wang , Cheng Chen , Ruoxiu Xiao