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A two-stage adaptive optimal design is an attractive option for increasing the efficiency of clinical trials. In these designs, based on interim data, the locally optimal dose is chosen for further exploration, which induces dependencies…

Methodology · Statistics 2019-05-24 Zhantao Lin , Nancy Flournoy , William F. Rosenberger

Low-rank matrix estimation under heavy-tailed noise is challenging, both computationally and statistically. Convex approaches have been proven statistically optimal but suffer from high computational costs, especially since robust loss…

Statistics Theory · Mathematics 2023-05-12 Yinan Shen , Jingyang Li , Jian-Feng Cai , Dong Xia

Consider semiparametric estimation where a doubly robust estimating function for a low-dimensional parameter is available, depending on two working models. With high-dimensional data, we develop regularized calibrated estimation as a…

Methodology · Statistics 2020-09-28 Satyajit Ghosh , Zhiqiang Tan

In this paper, we introduce a framework for solving finite-horizon multistage optimization problems under uncertainty in the presence of auxiliary data. We assume the joint distribution of the uncertain quantities is unknown, but noisy…

Machine Learning · Statistics 2019-04-29 Dimitris Bertsimas , Christopher McCord

Gaussian Process Regression (GPR) is widely used in statistics and machine learning for prediction tasks requiring uncertainty measures. Its efficacy depends on the appropriate specification of the mean function, covariance kernel function,…

Machine Learning · Computer Science 2024-09-20 Shifan Zhao , Jiaying Lu , Ji Yang , Edmond Chow , Yuanzhe Xi

In this paper, we consider the nonparametric least square regression in a Reproducing Kernel Hilbert Space (RKHS). We propose a new randomized algorithm that has optimal generalization error bounds with respect to the square loss, closing a…

Machine Learning · Computer Science 2019-05-28 Kwang-Sung Jun , Ashok Cutkosky , Francesco Orabona

In the nonparametric regression setting, we construct an estimator which is a continuous function interpolating the data points with high probability, while attaining minimax optimal rates under mean squared risk on the scale of H\"older…

Statistics Theory · Mathematics 2022-06-28 Julien Chhor , Suzanne Sigalla , Alexandre B. Tsybakov

The random forest (RF) algorithm has become a very popular prediction method for its great flexibility and promising accuracy. In RF, it is conventional to put equal weights on all the base learners (trees) to aggregate their predictions.…

Machine Learning · Statistics 2023-05-18 Xinyu Chen , Dalei Yu , Xinyu Zhang

Reduced-rank regression is a dimensionality reduction method with many applications. The asymptotic theory for reduced rank estimators of parameter matrices in multivariate linear models has been studied extensively. In contrast, few…

Statistics Theory · Mathematics 2017-10-13 Efstathia Bura , Sabrina Duarte , Liliana Forzani , Ezequiel Smucler , Mariela Sued

Regularized system identification has become a significant complement to more classical system identification. It has been numerically shown that kernel-based regularized estimators often perform better than the maximum likelihood estimator…

Machine Learning · Statistics 2025-03-18 Yue Ju , Bo Wahlberg , Håkan Hjalmarsson

Parameter reduction can enable otherwise infeasible design and uncertainty studies with modern computational science models that contain several input parameters. In statistical regression, techniques for sufficient dimension reduction…

Numerical Analysis · Mathematics 2018-12-12 Andrew T. Glaws , Paul G. Constantine , R. Dennis Cook

We study multistage distributionally robust linear optimization, where the uncertainty set is defined as a ball of distribution centered at a scenario tree using the nested distance. The resulting minimax problem is notoriously difficult to…

Optimization and Control · Mathematics 2024-07-24 Rui Gao , Rohit Arora , Yizhe Huang

For finite samples with binary outcomes penalized logistic regression such as ridge logistic regression (RR) has the potential of achieving smaller mean squared errors (MSE) of coefficients and predictions than maximum likelihood…

Methodology · Statistics 2021-01-28 Hana Šinkovec , Georg Heinze , Rok Blagus , Angelika Geroldinger

Nonparametric regression imputation is commonly used in missing data analysis. However, it suffers from the ``curse of dimension". The problem can be alleviated by the explosive sample size in the era of big data, while the large-scale data…

Methodology · Statistics 2023-09-26 Ruoyu Wang , Miaomiao Su , Qihua Wang

Feature-distributed data, referred to data partitioned by features and stored across multiple computing nodes, are increasingly common in applications with a large number of features. This paper proposes a two-stage relaxed greedy algorithm…

Machine Learning · Statistics 2024-03-12 Shuo-Chieh Huang , Ruey S. Tsay

Regularization aims to improve prediction performance of a given statistical modeling approach by moving to a second approach which achieves worse training error but is expected to have fewer degrees of freedom, i.e., better agreement…

Statistics Theory · Mathematics 2013-11-13 Shachar Kaufman , Saharon Rosset

High-dimensional sparse modeling via regularization provides a powerful tool for analyzing large-scale data sets and obtaining meaningful, interpretable models. The use of nonconvex penalty functions shows advantage in selecting important…

Methodology · Statistics 2016-05-12 Zemin Zheng , Yingying Fan , Jinchi Lv

This paper aims to solve a basic problem in distributed statistical inference: how many machines can we use in parallel computing? In kernel ridge regression, we address this question in two important settings: nonparametric estimation and…

Statistics Theory · Mathematics 2019-02-26 Meimei Liu , Zuofeng Shang , Guang Cheng

We are concerned with an approximation problem for a symmetric positive semidefinite matrix due to motivation from a class of nonlinear machine learning methods. We discuss an approximation approach that we call {matrix ridge…

Machine Learning · Statistics 2013-12-18 Zhihua Zhang

Meta-analysis methods are used to combine evidence from multiple studies. Meta-regression as well as model-based meta-analysis are extensions of standard pairwise meta-analysis in which information about study-level covariates and…

Methodology · Statistics 2022-02-02 Burak Kürsad Günhan , Christian Röver , Tim Friede
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