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Acute Kidney Injury (AKI), a sudden decline in kidney function, is associated with increased mortality, morbidity, length of stay, and hospital cost. Since AKI is sometimes preventable, there is great interest in prediction. Most existing…

Machine Learning · Computer Science 2019-03-06 Samuel J. Weisenthal , Caroline Quill , Samir Farooq , Henry Kautz , Martin S. Zand

The ICH E9(R1) Addendum (International Council for Harmonization 2019) suggests treatment-policy as one of several strategies for addressing intercurrent events such as treatment withdrawal when defining an estimand. This strategy requires…

Methodology · Statistics 2023-08-28 Suzie Cro , James H Roger , James R Carpenter

Patient monitoring is vital in all stages of care. We here report the development and validation of ICU length of stay and mortality prediction models. The models will be used in an intelligent ICU patient monitoring module of an…

Machine Learning · Computer Science 2021-05-11 Khalid Alghatani , Nariman Ammar , Abdelmounaam Rezgui , Arash Shaban-Nejad

Intensive care unit (ICU) is a crucial hospital department that handles life-threatening cases. Nowadays machine learning (ML) is being leveraged in healthcare ubiquitously. In recent years, management of ICU became one of the most…

Machine Learning · Computer Science 2025-05-26 Alexander Gabitashvili , Philipp Kellmeyer

The availability of downstream resources plays is critical in planning the admission of elective surgery patients. The most crucial one is inpatient beds. To ensure bed availability, hospitals may use machine learning (ML) models to predict…

Machine Learning · Computer Science 2025-07-30 Pieter Smet , Martina Doneda , Ettore Lanzarone , Giuliana Carello

Modern healthcare is ripe for disruption by AI. A game changer would be automatic understanding the latent processes from electronic medical records, which are being collected for billions of people worldwide. However, these healthcare…

Neural and Evolutionary Computing · Computer Science 2018-02-06 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh

Objective: To propose and retrospectively validate an integrated framework addressing three barriers to clinical translation of readmission prediction: lack of explainability, absence of deployment reliability infrastructure, and inadequate…

Machine Learning · Computer Science 2026-05-06 Isaac Tosin Adisa

Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an…

Viewing the trajectory of a patient as a dynamical system, a recurrent neural network was developed to learn the course of patient encounters in the Pediatric Intensive Care Unit (PICU) of a major tertiary care center. Data extracted from…

Machine Learning · Statistics 2017-01-25 M Aczon , D Ledbetter , L Ho , A Gunny , A Flynn , J Williams , R Wetzel

Cardiovascular diseases and heart failures in particular are the main cause of non-communicable disease mortality in the world. Constant patient monitoring enables better medical treatment as it allows practitioners to react on time and…

Artificial Intelligence · Computer Science 2021-04-21 Kordian Gontarska , Weronika Wrazen , Jossekin Beilharz , Robert Schmid , Lauritz Thamsen , Andreas Polze

Electronic Medical Records (EMR) are a rich source of patient information, including measurements reflecting physiologic signs and administered therapies. Identifying which variables are useful in predicting clinical outcomes can be…

Machine Learning · Statistics 2019-04-03 Eugene Laksana , Melissa Aczon , Long Ho , Cameron Carlin , David Ledbetter , Randall Wetzel

Background: Palliative care is referred to a set of programs for patients that suffer life-limiting illnesses. These programs aim to guarantee a minimum level of quality of life (QoL) for the last stage of life. They are currently based on…

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

Machine Learning · Computer Science 2025-10-29 Yong Huang , Zhongqi Yang , Amir Rahmani

Hospitalization of patients is one of the major factors for high wound care costs. Most patients do not acquire a wound which needs immediate hospitalization. However, due to factors such as delay in treatment, patient's non-compliance or…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Subba Reddy Oota , Vijay Rowtula , Shahid Mohammed , Jeffrey Galitz , Minghsun Liu , Manish Gupta

Deep-learning-based clinical decision support using structured electronic health records (EHR) has been an active research area for predicting risks of mortality and diseases. Meanwhile, large amounts of narrative clinical notes provide…

Computation and Language · Computer Science 2023-05-10 Weimin Lyu , Xinyu Dong , Rachel Wong , Songzhu Zheng , Kayley Abell-Hart , Fusheng Wang , Chao Chen

Intensive care units (ICU) generate long, dense and evolving streams of clinical information, where physicians must repeatedly reassess patient states under time pressure, underscoring a clear need for reliable AI decision support. Existing…

Artificial Intelligence · Computer Science 2026-05-14 Chengzhi Shen , Weixiang Shen , Tobias Susetzky , Chen , Chen , Jun Li , Yuyuan Liu , Xuepeng Zhang , Zhenyu Gong , Daniel Rueckert , Jiazhen Pan

Early hospital mortality prediction is critical as intensivists strive to make efficient medical decisions about the severely ill patients staying in intensive care units. As a result, various methods have been developed to address this…

Machine Learning · Computer Science 2019-02-12 Reza Sadeghi , Tanvi Banerjee , William Romine

Early detection of patients vulnerable to infections acquired in the hospital environment is a challenge in current health systems given the impact that such infections have on patient mortality and healthcare costs. This work is focused on…

Machine learning models that utilize patient data across time (rather than just the most recent measurements) have increased performance for many risk stratification tasks in the intensive care unit. However, many of these models and their…

Machine Learning · Computer Science 2021-09-24 Nari Johnson , Sonali Parbhoo , Andrew Slavin Ross , Finale Doshi-Velez

As more Intensive Care Unit (ICU) data becomes available, the interest in developing clinical prediction models to improve healthcare protocols increases. However, the lack of data quality still hinders clinical prediction using Machine…