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Heart failure (HF) is one of the leading causes of hospital admissions in the US. Readmission within 30 days after a HF hospitalization is both a recognized indicator for disease progression and a source of considerable financial burden to…

Machine Learning · Computer Science 2018-12-27 Ahmed Allam , Mate Nagy , George Thoma , Michael Krauthammer

Readmission prediction is a critical but challenging clinical task, as the inherent relationship between high-dimensional covariates and readmission is complex and heterogeneous. Despite this complexity, models should be interpretable to…

Methodology · Statistics 2025-07-10 Wei Wang , Angela Bailey , Christopher Tignanelli , Jared D. Huling

Monitoring patients in ICU is a challenging and high-cost task. Hence, predicting the condition of patients during their ICU stay can help provide better acute care and plan the hospital's resources. There has been continuous progress in…

Computation and Language · Computer Science 2020-01-03 Swaraj Khadanga , Karan Aggarwal , Shafiq Joty , Jaideep Srivastava

Deep learning architectures have an extremely high-capacity for modeling complex data in a wide variety of domains. However, these architectures have been limited in their ability to support complex prediction problems using insurance…

Clinical predictive algorithms are increasingly being used to form the basis for optimal treatment policies--that is, to enable interventions to be targeted to the patients who will presumably benefit most. Despite taking advantage of…

Applications · Statistics 2020-07-21 Ben J. Marafino , Alejandro Schuler , Vincent X. Liu , Gabriel J. Escobar , Mike Baiocchi

Machine learning models depend on the quality of input data. As electronic health records are widely adopted, the amount of data in health care is growing, along with complaints about the quality of medical notes. We use two prediction…

Computation and Language · Computer Science 2020-12-10 Chao-Chun Hsu , Shantanu Karnwal , Sendhil Mullainathan , Ziad Obermeyer , Chenhao Tan

Early identification of intensive care patients at risk of in-hospital mortality enables timely intervention and efficient resource allocation. Despite high predictive performance, existing machine learning approaches lack transparency and…

Machine Learning · Computer Science 2025-11-21 Alexander Bakumenko , Janine Hoelscher , Hudson Smith

Predicting discharge medications right after a patient being admitted is an important clinical decision, which provides physicians with guidance on what type of medication regimen to plan for and what possible changes on initial medication…

Computation and Language · Computer Science 2017-12-06 Yuan Yang , Pengtao Xie , Xin Gao , Carol Cheng , Christy Li , Hongbao Zhang , Eric Xing

Although not without controversy, readmission is entrenched as a hospital quality metric, with statistical analyses generally based on fitting a logistic-Normal generalized linear mixed model. Such analyses, however, ignore death as a…

Hospitalizations that follow closely on the heels of one or more emergency department visits are often symptoms of missed opportunities to form a proper diagnosis. These diagnostic errors imply a failure to recognize the need for…

Machine Learning · Computer Science 2024-07-02 Dat Hong , Philip M. Polgreen , Alberto Maria Segre

Accurately predicting hospital readmission risks using electronic health records (EHRs) is critical for effective patient management and healthcare resource allocation. Patient populations in health systems are highly heterogeneous across…

Electronic Health Records (EHRs) have been heavily used to predict various downstream clinical tasks such as readmission or mortality. One of the modalities in EHRs, clinical notes, has not been fully explored for these tasks due to its…

Computation and Language · Computer Science 2019-06-05 Bonggun Shin , Julien Hogan , Andrew B. Adams , Raymond J. Lynch , Rachel E. Patzer , Jinho D. Choi

Researchers are often faced with evaluating the effect of a policy or program that was simultaneously initiated across an entire population of units at a single point in time, and its effects over the targeted population can manifest at any…

Accurately predicting patients' risk of 30-day hospital readmission would enable hospitals to efficiently allocate resource-intensive interventions. We develop a new method, Categorical Co-Frequency Analysis (CoFA), for clustering diagnosis…

Applications · Statistics 2019-09-04 Hallee E. Wong , Brianna C. Heggeseth , Steven J. Miller

Intensive Care Units are complex, data-rich environments where critically ill patients are treated using variety of clinical equipment. The data collected using this equipment can be used clinical staff to gain insight into the condition of…

Human-Computer Interaction · Computer Science 2024-10-23 Marceli Wac , Raul Santos-Rodriguez , Chris McWilliams , Christopher Bourdeaux

Problem lists are intended to provide clinicians with a relevant summary of patient medical issues and are embedded in many electronic health record systems. Despite their importance, problem lists are often cluttered with resolved or…

Information Retrieval · Computer Science 2020-08-05 Justin Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

Hospital readmission within 30 days of discharge is a leading driver of morbidity, mortality, and avoidable healthcare expenditure in congestive heart failure (CHF). Current clinical risk stratification tools rely primarily on non-imaging…

Hospital inpatient care costs is the largest component of health care expenditures in the US. At the same time, the number of non-hospital rehabilitative settings, such as skilled nursing facilities (SNFs), has increased. Lower costs and…

Optimization and Control · Mathematics 2022-03-10 Oguzhan Alagoz , Sebastian A. Alvarez Avendaño , John Oruongo , Gabriel Zayas-Cabán

Accurate and interpretable mortality risk prediction in intensive care units (ICUs) remains a critical challenge due to the irregular temporal structure of electronic health records (EHRs), the complexity of longitudinal disease…

Machine Learning · Computer Science 2026-03-10 Zahra Jafari , Azadeh Zamanifar , Amirfarhad Farhadi

Early identification of patients at risk for clinical deterioration in the intensive care unit (ICU) remains a critical challenge. Delayed recognition of impending adverse events, including mortality, vasopressor initiation, and mechanical…

Machine Learning · Computer Science 2026-03-17 Binesh Sadanandan