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We present SIGMA-GEN, a unified framework for multi-identity preserving image generation. Unlike prior approaches, SIGMA-GEN is the first to enable single-pass multi-subject identity-preserved generation guided by both structural and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Oindrila Saha , Vojtech Krs , Radomir Mech , Subhransu Maji , Kevin Blackburn-Matzen , Matheus Gadelha

Many imaging techniques for biological systems -- like fixation of cells coupled with fluorescence microscopy -- provide sharp spatial resolution in reporting locations of individuals at a single moment in time but also destroy the dynamics…

Subcellular Processes · Quantitative Biology 2024-05-15 Christopher E. Miles , Scott A. McKinley , Fangyuan Ding , Richard B. Lehoucq

Nucleosome core particle is a dynamic structure -- DNA may transiently peel off the histone octamer surface due to thermal fluctuations or the action of chromatin remodeling enzymes. Partial DNA unwrapping enables easier access of…

Genomics · Quantitative Biology 2018-10-17 Răzvan V. Chereji , Alexandre V. Morozov

Image fusion technology is widely used to fuse the complementary information between multi-source remote sensing images. Inspired by the frontier of deep learning, this paper first proposes a heterogeneous-integrated framework based on a…

Image and Video Processing · Electrical Eng. & Systems 2024-05-15 Menghui Jiang , Huanfeng Shen , Jie Li , Liangpei Zhang

This paper presents a generic probabilistic framework for estimating the statistical dependency and finding the anatomical correspondences among an arbitrary number of medical images. The method builds on a novel formulation of the…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Xinzhe Luo , Xiahai Zhuang

Elastomeric mechanical metamaterials exhibit unconventional behaviour, emerging from their microstructures often deforming in a highly nonlinear and unstable manner. Such microstructural pattern transformations lead to non-local behaviour…

Soft Condensed Matter · Physics 2025-02-18 S. O. Sperling , T. Guo , R. H. J. Peerlings , V. G. Kouznetsova , M. G. D. Geers , O. Rokoš

The diverse combinations of novel building blocks offer a vast design space for hydrogen-boned frameworks (HOFs), rendering it a great promise for gas separation and purification. However, the underlying separation mechanism facilitated by…

Chemical Physics · Physics 2025-05-12 Yong Qiu , Lei Wang , Letian Chen , Yun Tian , Zhen Zhou , Jianzhong Wu

In this study, we present a conditional diffusion-transformer framework for generating ensembles of three-dimensional Escherichia coli genome conformations guided by Hi-C contact maps. Instead of producing a single deterministic structure,…

Machine Learning · Computer Science 2026-03-10 Mingxin Zhang , Xiaofeng Dai , Yu Yao , Ziqi Yin

Persistent homology, a central tool of topological data analysis, provides invariants of data called barcodes (also known as persistence diagrams). A barcode is simply a multiset of real intervals. Recent work of Edelsbrunner, Jablonski,…

Algebraic Topology · Mathematics 2020-10-12 Ulrich Bauer , Michael Lesnick

The recent advances in sequencing technologies enables the assembly of individual genomes to the reference quality. How to integrate multiple genomes from the same species and to make the integrated representation accessible to biologists…

Genomics · Quantitative Biology 2020-03-16 Heng Li , Xiaowen Feng , Chong Chu

Text-conditioned molecular generation aims to translate natural-language descriptions into chemical structures, enabling scientists to specify functional groups, scaffolds, and physicochemical constraints without handcrafted rules.…

Machine Learning · Computer Science 2025-11-18 Lingxiao Li , Haobo Zhang , Bin Chen , Jiayu Zhou

A boson sampler implements a restricted model of quantum computing. It is defined by the ability to sample from the distribution resulting from the interference of identical bosons propagating according to programmable, non-interacting…

Generative models, like large language models, are becoming increasingly relevant in our daily lives, yet a theoretical framework to assess their generalization behavior and uncertainty does not exist. Particularly, the problem of…

Machine Learning · Computer Science 2024-07-11 Sebastian G. Gruber , Florian Buettner

Ultra-cold atomic systems provide a versatile platform for exploring quantum phenomena, offering tunable interactions and diverse trapping geometries. In this study, we investigate a one-dimensional system of trapped fermionic atoms using…

Quantum Gases · Physics 2025-09-16 Francisco Figueiredo , Itzhak Roditi

This paper introduces new tools for genomic signal processing, which can assist for genomic attribute extracting or describing biologically meaningful features embedded in a DNA. The codongrams and a2grams are offered as an alternative to…

Other Quantitative Biology · Quantitative Biology 2015-03-10 E. A. Bouton , H. M. de Oliveira , R. M. Campello de Souza , N. S. Santos-Magalhaes

Image generation models trained on large datasets can synthesize high-quality images but often produce spatially inconsistent and distorted images due to limited information about the underlying structures and spatial layouts. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Hyundo Lee , Suhyung Choi , Inwoo Hwang , Byoung-Tak Zhang

Motivation: As cancer researchers have come to appreciate the importance of intratumor heterogeneity, much attention has focused on the challenges of accurately profiling heterogeneity in individual patients. Experimental technologies for…

Genomics · Quantitative Biology 2018-02-07 Theodore Roman , Lu Xie , Russell Schwartz

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

A key step in any resonant anomaly detection search is accurate modeling of the background distribution in each signal region. Data-driven methods like CATHODE accomplish this by training separate generative models on the complement of each…

High Energy Physics - Phenomenology · Physics 2025-04-08 Ranit Das , David Shih

This paper considers the difficulty in the set-system approach to generalizing graph theory. These difficulties arise categorically as the category of set-system hypergraphs is shown not to be cartesian closed and lacks enough projective…

Combinatorics · Mathematics 2019-05-06 Will Grilliette , Lucas J. Rusnak