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Cartesian tree matching is a form of generalized pattern matching where a substring of the text matches with the pattern if they share the same Cartesian tree. This form of matching finds application for time series of stock prices and can…

Data Structures and Algorithms · Computer Science 2024-11-20 Eric M. Osterkamp , Dominik Köppl

We study how the application of injective morphisms affects the number $r$ of equal-letter runs in the Burrows-Wheeler Transform (BWT). This parameter has emerged as a key repetitiveness measure in compressed indexing. We focus on the…

Formal Languages and Automata Theory · Computer Science 2025-04-25 Gabriele Fici , Giuseppe Romana , Marinella Sciortino , Cristian Urbina

The positional Burrows-Wheeler Transform (PBWT) is commonly used to store haplotype panels compactly in such a way that, given a query haplotype, we can quickly find the set maximal exact matches (SMEMs) between the query and the haplotypes…

Data Structures and Algorithms · Computer Science 2026-05-26 Travis Gagie

Enumerating characteristic substrings (e.g., maximal repeats, minimal unique substrings, and minimal absent words) in a given string has been an important research topic because there are a wide variety of applications in various areas such…

Data Structures and Algorithms · Computer Science 2021-03-03 Takaaki Nishimoto , Yasuo Tabei

We survey the different methods used for extending the BWT to collections of strings, following largely [Cenzato and Lipt\'ak, CPM 2022, Bioinformatics 2024]. We analyze the specific aspects and combinatorial properties of the resulting BWT…

Data Structures and Algorithms · Computer Science 2025-06-03 Davide Cenzato , Zsuzsanna Lipták , Nadia Pisanti , Giovanna Rosone , Marinella Sciortino

The Positional Burrows-Wheeler Transform (PBWT) is a fundamental data structure for the efficient representation and analysis of large-scale haplotype panels. For a panel of $h$ sequences $\{S_1, \dots, S_h\}$ over $m$ sites, a key…

Data Structures and Algorithms · Computer Science 2026-05-07 Paola Bonizzoni , Travis Gagie , Younan Gao

There are currently plenty of programs available for mapping short sequences (reads) to a genome. Most of them, however, including such popular and actively developed programs as Bowtie, BWA, TopHat and many others, are based on…

Genomics · Quantitative Biology 2019-08-06 Igor Seledtsov , Jaroslav Efremov , Vladimir Molodtsov , Victor Solovyev

Compressed suffix arrays (CSAs) index large repetitive collections and are key in many text applications. The r-index and its derivatives combine the run-length Burrows-Wheeler Transform (BWT) with suffix array sampling to achieve space…

Data Structures and Algorithms · Computer Science 2026-02-20 Diego Díaz-Domínguez , Veli Mäkinen

We present a new scalable, lightweight algorithm to incrementally construct the BWT and FM-index of large string sets such as those produced by Next Generation Sequencing. The algorithm is designed for massive parallelism and can…

Data Structures and Algorithms · Computer Science 2014-10-03 Jacopo Pantaleoni

We describe a grammar for DNA sequencing reads from which we can compute the BWT directly. Our motivation is to perform in succinct space genomic analyses that require complex string queries not yet supported by repetition-based…

Data Structures and Algorithms · Computer Science 2020-11-17 Diego Díaz-Domínguez , Gonzalo Navarro

When building Burrows-Wheeler Transforms (BWTs) of truly huge datasets, prefix-free parsing (PFP) can use an unreasonable amount of memory. In this paper we show how if a dataset can be broken down into small datasets that are not very…

Data Structures and Algorithms · Computer Science 2025-06-09 Diego Diaz-Dominguez , Travis Gagie , Veronica Guerrini , Ben Langmead , Zsuzsanna Liptak , Giovanni Manzini , Francesco Masillo , Vikram Shivakumar

In this paper, we describe a new type of match between a pattern and a text that aren't necessarily maximal in the query, but still contain useful matching information: locally maximal exact matches (LEMs). There are usually a large amount…

Data Structures and Algorithms · Computer Science 2025-05-22 Ahsan Sanaullah , Degui Zhi , Shaojie Zhang

Parameterized strings are a generalization of strings in that their characters are drawn from two different alphabets, where one is considered to be the alphabet of static characters and the other to be the alphabet of parameter characters.…

Data Structures and Algorithms · Computer Science 2022-09-01 Daiki Hashimoto , Diptarama Hendrian , Dominik Köppl , Ryo Yoshinaka , Ayumi Shinohara

The Gradient Boosted Tree (GBT) algorithm is one of the most popular machine learning algorithms used in production, for tasks that include Click-Through Rate (CTR) prediction and learning-to-rank. To deal with the massive datasets…

Machine Learning · Computer Science 2019-05-30 Theodore Vasiloudis , Hyunsu Cho , Henrik Boström

Recently, Holt and McMillan [Bionformatics 2014, ACM-BCB 2014] have proposed a simple and elegant algorithm to merge the Burrows-Wheeler transforms of a family of strings. In this paper we show that the H&M algorithm can be improved so…

Data Structures and Algorithms · Computer Science 2016-09-16 Giovanni Manzini

Motivation: The comparison of diverse genomic datasets is fundamental to understanding genome biology. Researchers must explore many large datasets of genome intervals (e.g., genes, sequence alignments) to place their experimental results…

Genomics · Quantitative Biology 2012-08-20 Ryan M. Layer , Kevin Skadron , Gabriel Robins , Ira M. Hall , Aaron R. Quinlan

The Binary Search Tree (BST) is average in computer science which supports a compact data structure in memory and oneself even conducts a row of quick algorithms, by which people often apply it in dynamical circumstance. Besides these…

Data Structures and Algorithms · Computer Science 2018-10-05 Yong Tan

In this paper we develop a theory describing how the extended Burrows-Wheeler Transform (eBWT) of a collection of DNA fragments tends to cluster together the copies of nucleotides sequenced from a genome G. Our theory accurately predicts…

Data Structures and Algorithms · Computer Science 2018-05-11 Nicola Prezza , Nadia Pisanti , Marinella Sciortino , Giovanna Rosone

A bit catastrophe, loosely defined, is when a change in just one character of a string causes a significant change in the size of the compressed string. We study this phenomenon for the Burrows-Wheeler Transform (BWT), a string transform at…

Data Structures and Algorithms · Computer Science 2025-06-10 Sara Giuliani , Shunsuke Inenaga , Zsuzsanna Lipták , Giuseppe Romana , Marinella Sciortino , Cristian Urbina

High-throughput sequencing technologies have led to explosive growth of genomic databases; one of which will soon reach hundreds of terabytes. For many applications we want to build and store indexes of these databases but constructing such…

Data Structures and Algorithms · Computer Science 2018-11-19 Christina Boucher , Travis Gagie , Alan Kuhnle , Ben Langmead , Giovanni Manzini , Taher Mun