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Related papers: Simulation of a Compton-based detector for low-dos…

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We present simulations of whole-body low-dose time-of-flight positron emission tomography (TOF-PET) based on the direct surface production [1] by 511 keV gamma rays of energetic electrons via the Photo-electric and Compton Effects,…

In positron emission tomography (PET), time-of-flight (TOF) information localizes source positions along lines of response. Cherenkov-radiator-integrated microchannel-plate photomultiplier tubes have achieved 30 ps TOF resolution,…

We propose PET scanners using low atomic number media that undergo a persistent local change of state along the paths of the Compton recoil electrons. Measurement of the individual scattering locations and angles, deposited energies, and…

We have used the TOPAS Geant4-based package to create a parametric simulation of a new TOF-PET scanner design based on a low atomic number scintillator. TOPAS was extended to provide complete information on individual particle position,…

Medical Physics · Physics 2023-10-03 Kepler Domurat-Sousa , Cameron Poe

Intraoperative Gamma Probe (IPG) remains the current gold standard modality for sentinel lymph node identification and tumor removal in cancer patients. However, even alongside the optical dyes they do not meet with <5% false negative rates…

Medical Physics · Physics 2022-01-26 S. Sajedi , L. Blackberg , S. Majewski , H. Sabet

The purpose of this study was to show how advanced concepts of compact, lossless and "Time Of Flight" (TOF) capable electronics similar to those foreseen for the LHC and ILC experiments could be fairly and easily transferred to the medical…

Instrumentation and Detectors · Physics 2009-08-03 P. -E. Vert , J. Lecoq , G. Montarou , N. Pauna , B. Joly , M. Boutemeur , H. Mathez , R. Gaglione , P. Le Dû

Modern PET systems reach a spatial resolution of 3-10 mm. A disadvantage of this technique is the diffusion of the positron before its decay with a typical range of ca. 1 mm (depending on its energy). This motion and Compton scattering of…

Instrumentation and Detectors · Physics 2012-02-03 C. Lang , D. Habs , P. G. Thirolf , A. Zoglauer

This master thesis presents a new type of Positron Emission TOF Apparatus using Liquid xenOn (PETALO). The detector is based in the Liquid Xenon Scintillating Cell (LXSC). The cell is a box filled with liquid xenon (LXe) whose transverse…

Medical Physics · Physics 2016-06-01 J. M. Benlloch-Rodriguez

PETALO (Positron Emission TOF Apparatus based on Liquid xenOn) exploits the unique characteristics of liquid xenon as a scintillator for use in a PET detector. Here initial simulation studies are detailed which highlight the potential of…

The ATLAS Forward Proton (AFP) detector is intended to measure protons scattered at small angles from the ATLAS interaction point. To this end, a combination of 3D Silicon pixel tracking modules and Quartz-Cherenkov time-of-flight (ToF)…

In this paper we prove that the choice of a suitable treatment of the scintillator surfaces, along with suitable photodetectors electronics and specific algorithms for raw data analysis, allow to achieve an optimal tradeoff between energy,…

Medical Physics · Physics 2012-03-02 Luigi Cosentino , Paolo Finocchiaro , Alfio Pappalardo , Franco Garibaldi

Time-Of-Flight (TOF) is a noble technique that is used in Positron Emission Tomography (PET) imaging worldwide. The scintillator based imaging system that is being used around the world for TOF-PET is very expensive. Multi-gap Resistive…

Instrumentation and Detectors · Physics 2018-07-02 Rajesh Ganai , Shaifali Mehta , Mehulkumar Shiroya , Mitali Mondal , Zubayer Ahammed , Subhasis Chattopadhyay

Accurate Time-of-Flight (TOF) measurement with sub-100 picosecond resolution is a critical requirement for particle identification in future high-energy physics experiments, such as the Belle II $K_{L}$ and Muon (KLM) detector upgrade.…

Instrumentation and Detectors · Physics 2026-05-14 Ziyi Yang , Xiyang Wang , Shiming Zou , Ting Wang , Kairui Huang , Wanyi Zhuang , Yicheng Pu , Xiaolong Wang

The EndoTOFPET-US project aims to jointly exploit Time-Of-Flight Positron Emission Tomography (TOFPET) and ultrasound endoscopy with a multi-modal instrument for the development of new biomarkers for pancreas and prostate oncology. The…

Instrumentation and Detectors · Physics 2013-03-20 Erika Garutti

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…

Nowadays, in Positron Emission Tomography (PET) systems, a Time of Flight information is used to improve the image reconstruction process. In Time of Flight PET (TOF-PET), fast detectors are able to measure the difference in the arrival…

We report on an hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA…

Cone beam computed tomography (CBCT) for breast imaging has potential to replace conventional mammograms. However, concerns over dose and image quality prevent CBBCT systems from the clinical trial phase to next stage. The time of flight…

Medical Physics · Physics 2021-02-01 Ignacio O. Romero , Changqing Li

For long time non-pure beta emitters are avoided from PET imaging due to extra dose and increase in background from Compton scattering. But advent of high-resolution Compton camera system opens up new domain of imaging. Various non-pure…

Medical Physics · Physics 2021-10-06 Satyajit Ghosh , Pragya Das

The imaging performance of a high-resolution preclinical microPET system employing liquid xenon as the gamma ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection…

Medical Physics · Physics 2012-03-23 A. Miceli , J. Glister , A. Andreyev , D. Bryman , L. Kurchaninov , P. Lu , A. Muennich , F. Retiere , V. Sossi
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