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Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

Fundus imaging is a critical tool in ophthalmology, with different imaging modalities offering unique advantages. For instance, fundus fluorescein angiography (FFA) can accurately identify eye diseases. However, traditional invasive FFA…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Chengzhou Yu , Huihui Fang , Hongqiu Wang , Ting Deng , Qing Du , Yanwu Xu , Weihua Yang

Diffusion models for image generation have been a subject of increasing interest due to their ability to generate diverse, high-quality images. Image generation has immense potential in medical imaging because open-source medical images are…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Benoit Freiche , Anthony El-Khoury , Ali Nasiri-Sarvi , Mahdi S. Hosseini , Damien Garcia , Adrian Basarab , Mathieu Boily , Hassan Rivaz

Synthesizing images of the eye fundus is a challenging task that has been previously approached by formulating complex models of the anatomy of the eye. New images can then be generated by sampling a suitable parameter space. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2017-02-01 Pedro Costa , Adrian Galdran , Maria Inês Meyer , Michael David Abràmoff , Meindert Niemeijer , Ana Maria Mendonça , Aurélio Campilho

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

Generative models are becoming popular for the synthesis of medical images. Recently, neural diffusion models have demonstrated the potential to generate photo-realistic images of objects. However, their potential to generate medical images…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Hazrat Ali , Shafaq Murad , Zubair Shah

The adoption of neural network models in medical imaging has been constrained by strict privacy regulations, limited data availability, high acquisition costs, and demographic biases. Deep generative models offer a promising solution by…

Image and Video Processing · Electrical Eng. & Systems 2025-06-16 Zuzanna Skorniewska , Bartlomiej W. Papiez

In this paper, a hierarchical image matting model is proposed to extract blood vessels from fundus images. More specifically, a hierarchical strategy utilizing the continuity and extendibility of retinal blood vessels is integrated into the…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 Zhun Fan , Jiewei Lu , Wenji Li , Caimin Wei , Han Huang , Xinye Cai , Xinjian Chen

Retinal vessel segmentation is a fundamental step in screening, diagnosis, and treatment of various cardiovascular and ophthalmic diseases. Robustness is one of the most critical requirements for practical utilization, since the test images…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Xu Sun , Huihui Fang , Yehui Yang , Dongwei Zhu , Lei Wang , Junwei Liu , Yanwu Xu

Blood vessel networks, represented as 3D graphs, help predict disease biomarkers, simulate blood flow, and aid in synthetic image generation, relevant in both clinical and pre-clinical settings. However, generating realistic vessel graphs…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Chinmay Prabhakar , Suprosanna Shit , Fabio Musio , Kaiyuan Yang , Tamaz Amiranashvili , Johannes C. Paetzold , Hongwei Bran Li , Bjoern Menze

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Generalization in medical segmentation models is challenging due to limited annotated datasets and imaging variability. To address this, we propose Retinal Layout-Aware Diffusion (RLAD), a novel diffusion-based framework for generating…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Jonathan Fhima , Jan Van Eijgen , Lennert Beeckmans , Thomas Jacobs , Moti Freiman , Luis Filipe Nakayama , Ingeborg Stalmans , Chaim Baskin , Joachim A. Behar

Retinal fundus images play a crucial role in the early detection of eye diseases. However, the impact of technical factors on these images can pose challenges for reliable AI applications in ophthalmology. For example, large fundus cohorts…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Sarah Müller , Lisa M. Koch , Hendrik P. A. Lensch , Philipp Berens

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Machine learning has significantly advanced healthcare by aiding in disease prevention and treatment identification. However, accessing patient data can be challenging due to privacy concerns and strict regulations. Generating synthetic,…

Carrying out clinical diagnosis of retinal vascular degeneration using Fluorescein Angiography (FA) is a time consuming process and can pose significant adverse effects on the patient. Angiography requires insertion of a dye that may cause…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sharif Amit Kamran , Khondker Fariha Hossain , Alireza Tavakkoli , Stewart Lee Zuckerbrod , Salah A. Baker , Kenton M. Sanders

Image synthesis approaches, e.g., generative adversarial networks, have been popular as a form of data augmentation in medical image analysis tasks. It is primarily beneficial to overcome the shortage of publicly accessible data and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Shiyi Du , Xiaosong Wang , Yongyi Lu , Yuyin Zhou , Shaoting Zhang , Alan Yuille , Kang Li , Zongwei Zhou

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti
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