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Group testing with inhibitors (GTI) introduced by Farach at al. is studied in this paper. There are three types of items, $d$ defectives, $r$ inhibitors and $n-d-r$ normal items in a population of $n$ items. The presence of any inhibitor in…

Information Theory · Computer Science 2014-12-16 Abhinav Ganesan , Javad Ebrahimi , Sidharth Jaggi , Venkatesh Saligrama

In this paper, an information theoretic analysis on non-adaptive group testing schemes based on sparse pooling graphs is presented. The binary status of the objects to be tested are modeled by i.i.d. Bernoulli random variables with…

Information Theory · Computer Science 2013-04-29 Tadashi Wadayama

In multistage group testing, the tests within the same stage are considered nonadaptive, while those conducted across different stages are adaptive. Specifically, when the pools within the same stage are disjoint, meaning that the entire…

Information Theory · Computer Science 2025-07-10 Guojiang Shao

Among the challenges that the COVID-19 pandemic outbreak revealed is the problem to reduce the number of tests required for identifying the virus carriers in order to contain the viral spread while preserving the tests reliability. To cope…

Information Theory · Computer Science 2021-12-24 Catherine A. Haddad-Zaaknoon

Combinatorial group testing (CGT) is used to identify defective items from a set of items by grouping them together and performing a small number of tests on the groups. Recently, group testing has been used to design efficient COVID-19…

Discrete Mathematics · Computer Science 2022-11-02 Thais Bardini Idalino , Lucia Moura

In group sequential designs, where several data looks are conducted for early stopping, we generally assume the vector of test statistics from the sequential analyses follows (at least approximately or asymptotially) a multivariate normal…

Statistics Theory · Mathematics 2024-04-22 Long-Hao Xu , Tobias Mütze , Frank Konietschke , Tim Friede

Detection of rare traits or diseases in a large population is challenging. Pool testing allows covering larger swathes of population at a reduced cost, while simplifying logistics. However, testing precision decreases as it becomes unclear…

Information Theory · Computer Science 2021-06-22 Éric Brier , Megi Dervishi , Rémi Géraud-Stewart , David Naccache , Ofer Yifrach-Stav

In industrial engineering and manufacturing, quality control is an essential part of the production process of a product. To ensure proper functionality of a manufactured good, rigorous testing has to be performed to identify defective…

Methodology · Statistics 2025-04-02 Michael Balzer

In group testing, the task is to determine the distinguished members of a set of objects L by asking subset queries of the form ``does the subset Q of L contain a distinguished object?'' The primary biological application of group testing…

Combinatorics · Mathematics 2008-02-03 Emanuel Knill , S. Muthukrishnan

Pooled testing is a common strategy for public health disease screening under limited testing resources, allowing multiple biological samples to be tested together with the resources of a single test, at the cost of reduced individual…

Computer Science and Game Theory · Computer Science 2026-02-02 Nicholas Lopez , Francisco Marmolejo-Cossío , Jose Roberto Tello Ayala , David C. Parkes

An instance of a group testing problem is a set of objects $\cO$ and an unknown subset $P$ of $\cO$. The task is to determine $P$ by using queries of the type ``does $P$ intersect $Q$'', where $Q$ is a subset of $\cO$. This problem occurs…

Combinatorics · Mathematics 2016-09-06 Emanuel Knill

Group testing is a well known search problem that consists in detecting up to $s$ defective elements of the set $[t]=\{1,\ldots,t\}$ by carrying out tests on properly chosen subsets of $[t]$. In classical group testing the goal is to find…

Information Theory · Computer Science 2016-07-05 A. G. D'yachkov , I. V. Vorobyev , N. A. Polyanskii , V. Yu. Shchukin

We propose a novel group testing method, termed semi-quantitative group testing, motivated by a class of problems arising in genome screening experiments. Semi-quantitative group testing (SQGT) is a (possibly) non-binary pooling scheme that…

Information Theory · Computer Science 2015-05-28 Amin Emad , Olgica Milenkovic

Group testing techniques are widely used in resource-constrained settings, such as infectious-disease screening, blood safety, DNA library screening, and industrial inspection, where the efficient use of limited testing resources depends…

Methodology · Statistics 2026-04-29 Chi-Kuang Yeh , Weng Kee Wong , Julie Zhou

Genome-wide association analysis has generated much discussion about how to preserve power to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multiple testing procedure that facilitates the…

Statistics Theory · Mathematics 2007-06-13 Kathryn Roeder , Bernie Devlin , Larry Wasserman

Adaptive designs have been proposed for clinical trials in which the nuisance parameters or alternative of interest are unknown or likely to be misspecified before the trial. Whereas most previous works on adaptive designs and mid-course…

Methodology · Statistics 2011-05-18 Jay Bartroff , Tze Leung Lai

An important task in early phase drug development is to identify patients, which respond better or worse to an experimental treatment. While a variety of different subgroup identification methods have been developed for the situation of…

Methodology · Statistics 2020-01-22 Marius Thomas , Björn Bornkamp , Heidi Seibold

Polymerase chain reaction (PCR) testing is the gold standard for diagnosing COVID-19. PCR amplifies the virus DNA 40 times to produce measurements of viral loads that span seven orders of magnitude. Unfortunately, the outputs of these tests…

Quantitative Methods · Quantitative Biology 2022-01-19 Hsin-Po Wang , Ryan Gabrys , Alexander Vardy

When testing for infections, the standard method is to test each subject individually. If testing methodology is such that samples from multiple subjects can be efficiently combined and tested at once, yielding a positive results if any one…

Methodology · Statistics 2020-04-01 Anže Slosar

We consider the nonadaptive group testing with N items, of which $K = \Theta(N^\theta)$ are defective. We study a test design in which each item appears in nearly the same number of tests. For each item, we independently pick L tests…

Information Theory · Computer Science 2018-09-26 Oliver Johnson , Matthew Aldridge , Jonathan Scarlett