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Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…
Recent advancements in digital pathology have led to the development of numerous foundational models that utilize self-supervised learning on patches extracted from gigapixel whole slide images (WSIs). While this approach leverages vast…
Almost every single image restoration problem has a closely related parameter, such as the scale factor in super-resolution, the noise level in image denoising, and the quality factor in JPEG deblocking. Although recent studies on image…
In recent years, deep neural networks (DNNs) have demonstrated remarkable performance in pathology applications, potentially even outperforming expert pathologists due to their ability to learn subtle features from large datasets. One…
The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…
Traditional staining normalization approaches, e.g. Macenko, typically rely on the choice of a single representative reference image, which may not adequately account for the diverse staining patterns of datasets collected in practical…
While human observers are able to cope with variations in color and appearance of histological stains, digital pathology algorithms commonly require a well-normalized setting to achieve peak performance, especially when a limited amount of…
The variation in histologic staining between different medical centers is one of the most profound challenges in the field of computer-aided diagnosis. The appearance disparity of pathological whole slide images causes algorithms to become…
In the practical application of restoring low-resolution gray-scale images, we generally need to run three separate processes of image colorization, super-resolution, and dows-sampling operation for the target device. However, this pipeline…
Stain variation is a unique challenge associated with automated analysis of digital pathology. Numerous methods have been developed to improve the robustness of machine learning methods to stain variation, but comparative studies have…
The shift towards end-to-end deep learning has brought unprecedented advances in many areas of computer vision. However, deep neural networks are trained on images with resolutions that rarely exceed $1,000 \times 1,000$ pixels. The growing…
The detection of manufacturing errors is crucial in fabrication processes to ensure product quality and safety standards. Since many defects occur very rarely and their characteristics are mostly unknown a priori, their detection is still…
Image denoising methods must effectively model, implicitly or explicitly, the vast diversity of patterns and textures that occur in natural images. This is challenging, even for modern methods that leverage deep neural networks trained to…
Recently, tremendous human-designed and automatically searched neural networks have been applied to image denoising. However, previous works intend to handle all noisy images in a pre-defined static network architecture, which inevitably…
Supervised semantic segmentation normally assumes the test data being in a similar data domain as the training data. However, in practice, the domain mismatch between the training and unseen data could lead to a significant performance…
The advancement of imaging devices and countless images generated everyday pose an increasingly high demand on image denoising, which still remains a challenging task in terms of both effectiveness and efficiency. To improve denoising…
Many problems in image processing and computer vision (e.g. colorization, style transfer) can be posed as 'manipulating' an input image into a corresponding output image given a user-specified guiding signal. A holy-grail solution towards…
The different stain styles of cytopathological images have a negative effect on the generalization ability of automated image analysis algorithms. This article proposes a new framework that normalizes the stain style for cytopathological…
Due to the fast inference and good performance, discriminative learning methods have been widely studied in image denoising. However, these methods mostly learn a specific model for each noise level, and require multiple models for…
In this paper, we propose a state-of-the-art video denoising algorithm based on a convolutional neural network architecture. Previous neural network based approaches to video denoising have been unsuccessful as their performance cannot…