English
Related papers

Related papers: Imperfect Narrow Escape problem

200 papers

The problem of the time required for a diffusing molecule, within a large bounded domain, to first locate a small target is prevalent in biological modeling. Here we study this problem for a small spherical target. We develop uniform in…

Biological Physics · Physics 2013-08-06 Samuel A. Isaacson , Jay Newby

The exit problem for small perturbations of a dynamical system in a domain is considered. It is assumed that the unperturbed dynamical system and the domain satisfy the Levinson conditions. We assume that the random perturbation affects the…

Probability · Mathematics 2010-06-15 Sergio Angel Almada Monter , Yuri Bakhtin

We consider linear reaction--diffusion problems with mixed Diriclet-Neumann-Robin conditions. The diffusion matrix, reaction coefficient, and the coefficient in the Robin boundary condition are defined with an uncertainty which allow…

Numerical Analysis · Mathematics 2014-07-29 O. Mali , S. Repin

We consider Brownian motion in a circular disk $\Omega$, whose boundary $\p\Omega$ is reflecting, except for a small arc, $\p\Omega_a$, which is absorbing. As $\epsilon=|\partial \Omega_a|/|\partial \Omega|$ decreases to zero the mean time…

Mathematical Physics · Physics 2007-05-23 A. Singer , Z. Schuss , D. Holcman

In this paper we apply the differential inequality technique of Payne {\it et. al} \cite{Payne&SchaeferRobin08} to show that a reaction-diffusion system admits blow-up solutions, and to determine an upper bound for the blow-up time. For a…

Analysis of PDEs · Mathematics 2015-09-10 Li-Chang Hung

We present two novel additions to the semi-analytic solution of Lyman $\alpha$ (Ly$\alpha$) radiative transfer in spherical geometry: (1) implementation of the correct boundary condition for a steady source, and (2) solution of the…

Earth and Planetary Astrophysics · Physics 2022-08-03 B. Connor McClellan , Shane Davis , Phil Arras

We consider Brownian motion in a bounded domain $\Omega$ on a two-dimensional Riemannian manifold $(\Sigma,g)$. We assume that the boundary $\p\Omega$ is smooth and reflects the trajectories, except for a small absorbing arc…

Mathematical Physics · Physics 2007-05-23 A. Singer , Z. Schuss , D. Holcman

We study the noise-driven escape of active Brownian particles (ABPs) and run-and-tumble particles (RTPs) from confining potentials. In the small noise limit, we provide an exact expression for the escape rate in term of a variational…

Soft Condensed Matter · Physics 2019-07-03 Eric Woillez , Yongfeng Zhao , Yariv Kafri , Vivien Lecomte , Julien Tailleur

We consider a random walk in confined geometry, starting from a site and eventually reaching a target site. We calculate analytically the distribution of the occupation time on a third site, before reaching the target site. The obtained…

Statistical Mechanics · Physics 2009-11-13 S. Condamin , V. Tejedor , O. Benichou

We develop an immersed-boundary approach to modeling reaction-diffusion processes in dispersions of reactive spherical particles, from the diffusion-limited to the reaction-limited setting. We represent each reactive particle with a…

Numerical Analysis · Mathematics 2015-06-16 A. Pal Singh Bhalla , B. E. Griffith , N. A. Patankar , A. Donev

We present a fully computable a posteriori error estimator for piecewise linear finite element approximations of reaction-diffusion problems with mixed boundary conditions and piecewise constant reaction coefficient formulated in arbitrary…

Numerical Analysis · Mathematics 2015-07-06 Mark Ainsworth , Tomáš Vejchodský

The radiation (reaction, Robin) boundary condition for the continuum diffusion equation is widely used in chemical and biological applications to express reactive boundaries. The underlying trajectories of the diffusing particles are…

Mathematical Physics · Physics 2007-09-02 A. Singer , Z. Schuss , D. Holcman

We present a unified approach to characterising fast-reaction limits of systems of either two reaction-diffusion equations, or one reaction-diffusion equation and one ordinary differential equation, on unbounded domains, motivated by models…

Analysis of PDEs · Mathematics 2016-04-26 E. C. M. Crooks , D. Hilhorst

Many problems in physics, biology, and economics depend upon the duration of time required for a diffusing particle to cross a boundary. As such, calculations of the distribution of first passage time, and in particular the mean first…

Biological Physics · Physics 2021-05-26 Matthew J Simpson , Daniel J Vandenheuvel , Joshua M Wilson , Scott W McCue , Elliot J Carr

The diffusion of a reactant to a binding target plays a key role in many biological processes. The reaction-radius at which the reactant and target may interact is often a small parameter relative to the diameter of the domain in which the…

Subcellular Processes · Quantitative Biology 2016-10-26 Sam Isaacson , Ava Mauro , Jay Newby

We present an approximate analytical expression for the escape rate of time-dependent driven stochastic processes with an absorbing boundary such as the driven leaky integrate-and-fire model for neural spiking. The novel approximation is…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Michael Schindler , Peter Talkner , Peter Hänggi

We investigate a diffusive motion of a system of interacting Brownian particles in quasi-one-dimensional micropores. In particular, we consider a semi-infinite 1D geometry with a partially absorbing boundary and the hard-core inter-particle…

Statistical Mechanics · Physics 2012-03-06 Artem Ryabov , Petr Chvosta

We study the dynamics of one-dimensional active particles confined in a double-well potential, focusing on the escape properties of the system, such as the mean escape time from a well. We first consider a single-particle both in near and…

Statistical Mechanics · Physics 2022-03-15 Lorenzo Caprini , Fabio Cecconi , Umberto Marini Bettolo Marconi

In this paper, we investigate the effects of stochastic resetting on diffusion in $\R^d\backslash \calU$, where $\calU$ is a bounded obstacle with a partially absorbing surface $\partial \calU$. We begin by considering a Robin boundary…

Statistical Mechanics · Physics 2022-06-29 Paul C. Bressloff

We introduce and investigate the escape problem for random walkers that may eventually die, decay, bleach, or lose activity during their diffusion towards an escape or reactive region on the boundary of a confining domain. In the case of a…

Chemical Physics · Physics 2020-01-03 D. S. Grebenkov , J. -F. Rupprecht