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Computing atomic-scale properties of chemically disordered materials requires an efficient exploration of their vast configuration space. Traditional approaches such as Monte Carlo or Special Quasirandom Structures either entail sampling an…

Materials Science · Physics 2026-03-17 Maciej J. Karcz , Luca Messina , Eiji Kawasaki , Emeric Bourasseau

Optimizing a neural network's performance is a tedious and time taking process, this iterative process does not have any defined solution which can work for all the problems. Optimization can be roughly categorized into - Architecture and…

Machine Learning · Computer Science 2019-12-16 Siddhartha Dhar Choudhury , Shashank Pandey , Kunal Mehrotra

Optimizing molecular properties while preserving biological activity is a central challenge in drug design. Bioisosteric replacement, which substitutes a molecular fragment with a chemically or biologically analogous moiety, offers a…

Biomolecules · Quantitative Biology 2025-12-04 Hyeongwoo Kim , Seokhyun Moon , Wonho Zhung , Shinwoo Kim , Jaechang Lim , Woo Youn Kim

The inner structure of a material is called microstructure. It stores the genesis of a material and determines all its physical and chemical properties. While microstructural characterization is widely spread and well known, the…

Computer Vision and Pattern Recognition · Computer Science 2018-02-16 Seyed Majid Azimi , Dominik Britz , Michael Engstler , Mario Fritz , Frank Mücklich

The discovery of inorganic crystal structures with targeted properties is a significant challenge in materials science. Generative models, especially state-of-the-art diffusion models, offer the promise of modeling complex data…

Machine learning, especially deep learning, is dramatically changing the methods associated with optical thin-film inverse design. The vast majority of this research has focused on the parameter optimization (layer thickness, and structure…

Machine Learning · Computer Science 2021-02-19 Anqing Jiang , Liangyao Chen , Osamu Yoshie

The challenge of discovering new molecules with desired properties is crucial in domains like drug discovery and material design. Recent advances in deep learning-based generative methods have shown promise but face the issue of sample…

Biomolecules · Quantitative Biology 2024-12-31 Hyeonah Kim , Minsu Kim , Sanghyeok Choi , Jinkyoo Park

In this study, we developed an inverse analysis framework that proposes a microstructure for dual-phase (DP) steel that exhibits high strength and ductility. The inverse analysis method proposed in this study involves repeated random…

Computational Engineering, Finance, and Science · Computer Science 2024-10-15 Misato Suzuki , Kazuyuki Shizawa , Mayu Muramatsu

Bridging generative foundation models with non-equilibrium thin-film synthesis remains a central challenge, limiting the practical impact of AI-driven materials discovery on semiconductor dielectrics. Here, we introduce IDEAL (Inverse…

Materials Science · Physics 2026-03-11 Bonwook Gu , Trinh Ngoc Le , Wonjoong Kim , Zunair Masroor , Han-Bo-Ram Lee

Materials science inherently spans disciplines: experimentalists use advanced microscopy to uncover micro- and nanoscale structure, while theorists and computational scientists develop models that link processing, structure, and properties.…

Machine Learning · Computer Science 2026-03-25 Simon Daubner , Alexander E. Cohen , Benjamin Dörich , Samuel J. Cooper

A key challenge in metasurface design is the development of algorithms that can effectively and efficiently produce high performance devices. Design methods based on iterative optimization can push the performance limits of metasurfaces,…

Optical materials with special optical properties are widely used in a broad span of technologies, from computer displays to solar energy utilization leading to large dataset accumulated from years of extensive materials synthesis and…

Materials Science · Physics 2020-11-26 Rongzhi Dong , Yabo Dan , Xiang Li , Jianjun Hu

Electromagnetic metasurfaces have attracted significant interest recently due to their low profile and advantageous applications. Practically, many metasurface designs start with a set of constraints for the radiated far-field, such as…

Materials Science · Physics 2022-04-04 Stewart Pearson , Parinaz Naseri , Sean V. Hum

The mitigation of material defects from additive manufacturing (AM) processes is critical to reliability in their fabricated parts and is enabled by modeling the complex relations between available build monitoring signals and final…

Applied Physics · Physics 2024-02-26 Qixiang Luo , John D. Shimanek , Timothy W. Simpson , Allison M. Beese

In comparison to classical shallow representation learning techniques, deep neural networks have achieved superior performance in nearly every application benchmark. But despite their clear empirical advantages, it is still not well…

Machine Learning · Computer Science 2022-01-11 Calvin Murdock , George Cazenavette , Simon Lucey

The ability to create complex geometries with tailored material properties has brought interest in using additive manufacturing (AM) techniques in various industrial applications. However, the complex relationship between AM process…

Machine learning-based compact models provide a rapid and efficient approach for estimating device behavior across multiple input parameter variations. In this study, we introduce two reverse-design algorithms that utilize these compact…

Emerging Technologies · Computer Science 2025-08-29 Diego Ferrer , Jack Hutchins , Revanth Koduru , Sumeet Kumar Gupta , Admedullah Aziz

The synthesis of a metasurface exhibiting a specific set of desired scattering properties is a time-consuming and resource-demanding process, which conventionally relies on many cycles of full-wave simulations. It requires an experienced…

Signal Processing · Electrical Eng. & Systems 2021-09-15 Parinaz Naseri , Sean V. Hum

Directly manipulating the atomic structure to achieve a specific property is a long pursuit in the field of materials. However, hindered by the disordered, non-prototypical glass structure and the complex interplay between structure and…

Materials Science · Physics 2021-11-10 Qi Wang , Longfei Zhang

The intricate microstructure serves as the cornerstone for the composition/processing-structure-property (CPSP) connection in multiphase alloys. Traditional alloy design methods often overlook microstructural details, which diminishes the…

Materials Science · Physics 2024-09-05 Xudong Ma , Yuqi Zhang , Chenchong Wang , Ming Wang , Mingxin Huang , Wei Xu