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Convolutional neural networks trained on publicly available medical imaging datasets (source domain) rarely generalise to different scanners or acquisition protocols (target domain). This motivates the active field of domain adaptation.…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Thomas Varsavsky , Mauricio Orbes-Arteaga , Carole H. Sudre , Mark S. Graham , Parashkev Nachev , M. Jorge Cardoso

Machine learning traditionally assumes that the training and testing data are distributed independently and identically. However, in many real-world settings, the data distribution can shift over time, leading to poor generalization of…

Machine Learning · Computer Science 2024-02-19 Sepidehsadat Hosseini , Mengyao Zhai , Hossein Hajimirsadegh , Frederick Tung

The main challenge in domain generalization (DG) is to handle the distribution shift problem that lies between the training and test data. Recent studies suggest that test-time training (TTT), which adapts the learned model with test data,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Liang Chen , Yong Zhang , Yibing Song , Ying Shan , Lingqiao Liu

In this paper, we address domain shifts in pathological images by focusing on shifts within whole slide images~(WSIs), such as patient characteristics and tissue thickness, rather than shifts between hospitals. Traditional approaches rely…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Yuki Shigeyasu , Shota Harada , Akihiko Yoshizawa , Kazuhiro Terada , Naoki Nakazima , Mariyo Kurata , Hiroyuki Abe , Tetsuo Ushiku , Ryoma Bise

Distribution shift presents a significant challenge in machine learning, where models often underperform during the test stage when faced with a different distribution than the one they were trained on. This paper focuses on domain shifts,…

Machine Learning · Computer Science 2024-03-19 Huaxiu Yao , Xinyu Yang , Xinyi Pan , Shengchao Liu , Pang Wei Koh , Chelsea Finn

Generalizability of deep learning models may be severely affected by the difference in the distributions of the train (source domain) and the test (target domain) sets, e.g., when the sets are produced by different hardware. As a…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Ivan Zakazov , Vladimir Shaposhnikov , Iaroslav Bespalov , Dmitry V. Dylov

Deep learning models perform best when tested on target (test) data domains whose distribution is similar to the set of source (train) domains. However, model generalization can be hindered when there is significant difference in the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-19 Pulkit Khandelwal , Paul Yushkevich

Despite domain generalization (DG) has significantly addressed the performance degradation of pre-trained models caused by domain shifts, it often falls short in real-world deployment. Test-time adaptation (TTA), which adjusts a learned…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Xingguo Lv , Xingbo Dong , Liwen Wang , Jiewen Yang , Lei Zhao , Bin Pu , Zhe Jin , Xuejun Li

Data samples generated by several real world processes are dynamic in nature \textit{i.e.}, their characteristics vary with time. Thus it is not possible to train and tackle all possible distributional shifts between training and inference,…

Machine Learning · Computer Science 2021-10-22 Prabhu Teja Sivaprasad , François Fleuret

Preparing and scanning histopathology slides consists of several steps, each with a multitude of parameters. The parameters can vary between pathology labs and within the same lab over time, resulting in significant variability of the…

Computer Vision and Pattern Recognition · Computer Science 2018-01-11 Maxime W. Lafarge , Josien P. W. Pluim , Koen A. J. Eppenhof , Pim Moeskops , Mitko Veta

Domain generalization (DG) is a fundamental yet very challenging research topic in machine learning. The existing arts mainly focus on learning domain-invariant features with limited source domains in a static model. Unfortunately, there is…

Machine Learning · Computer Science 2022-05-30 Zhishu Sun , Zhifeng Shen , Luojun Lin , Yuanlong Yu , Zhifeng Yang , Shicai Yang , Weijie Chen

Domain adaption (DA) and domain generalization (DG) are two closely related methods which are both concerned with the task of assigning labels to an unlabeled data set. The only dissimilarity between these approaches is that DA can access…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 Mohammad Mahfujur Rahman , Clinton Fookes , Mahsa Baktashmotlagh , Sridha Sridharan

Cross-modal MRI segmentation is of great value for computer-aided medical diagnosis, enabling flexible data acquisition and model generalization. However, most existing methods have difficulty in handling local variations in domain shift…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Bingnan Li , Zhitong Gao , Xuming He

When machine learning models are deployed on a test distribution different from the training distribution, they can perform poorly, but overestimate their performance. In this work, we aim to better estimate a model's performance under…

Machine Learning · Computer Science 2020-07-08 Ching-Yao Chuang , Antonio Torralba , Stefanie Jegelka

Machine learning is driven by data, yet while their availability is constantly increasing, training data require laborious, time consuming and error-prone labelling or ground truth acquisition, which in some cases is very difficult or even…

Computer Vision and Pattern Recognition · Computer Science 2019-09-25 Vasileios Gkitsas , Antonis Karakottas , Nikolaos Zioulis , Dimitrios Zarpalas , Petros Daras

Model generalization capacity at domain shift (e.g., various imaging protocols and scanners) is crucial for deep learning methods in real-world clinical deployment. This paper tackles the challenging problem of domain generalization, i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Quande Liu , Qi Dou , Pheng-Ann Heng

Medical Image Analysis (MedIA) has emerged as a crucial tool in computer-aided diagnosis systems, particularly with the advancement of deep learning (DL) in recent years. However, well-trained deep models often experience significant…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Ziwei Niu , Shuyi Ouyang , Shiao Xie , Yen-wei Chen , Lanfen Lin

Deep learning models have exhibited exceptional effectiveness in Computational Pathology (CPath) by tackling intricate tasks across an array of histology image analysis applications. Nevertheless, the presence of out-of-distribution data…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Mostafa Jahanifar , Manahil Raza , Kesi Xu , Trinh Vuong , Rob Jewsbury , Adam Shephard , Neda Zamanitajeddin , Jin Tae Kwak , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

To deal with the domain shift between training and test samples, current methods have primarily focused on learning generalizable features during training and ignore the specificity of unseen samples that are also critical during the test.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Jian Zhang , Lei Qi , Yinghuan Shi , Yang Gao