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A fundamental objective of materials modeling is identifying atomic structures that align with experimental observables. Conventional approaches for disordered materials involve sampling from thermodynamic ensembles and hoping for an…

Materials Science · Physics 2025-09-30 Tigany Zarrouk , Miguel A. Caro

We introduce a generative model for protein backbone design utilizing geometric products and higher order message passing. In particular, we propose Clifford Frame Attention (CFA), an extension of the invariant point attention (IPA)…

Machine Learning · Computer Science 2024-11-11 Simon Wagner , Leif Seute , Vsevolod Viliuga , Nicolas Wolf , Frauke Gräter , Jan Stühmer

Accounting for nuclear quantum effects (NQEs) can significantly alter material properties at finite temperatures. Atomic modeling using the path-integral molecular dynamics (PIMD) method can fully account for such effects, but requires…

Materials Science · Physics 2025-05-21 A. A. Solovykh , N. E. Rybin , I. S. Novikov , A. V. Shapeev

This work presents a novel approach to improve phase identification in nanomechanical property maps of multiphase materials, such as those obtained by nanoindentation or atomic force microscopy (AFM). A major challenge in validating…

Materials Science · Physics 2026-03-03 David Mercier , Yasmine El Gharoussi

Time delays are components that make time-lag in systems response. They arise in physical, chemical, biological and economic systems, as well as in the process of measurement and computation. In this work, we implement Genetic Algorithm…

Systems and Control · Computer Science 2012-04-05 Andri Mirzal , Shinichiro Yoshii , Masashi Furukawa

Informatics-driven approaches, such as machine learning and sequential experimental design, have shown the potential to drastically impact next-generation materials discovery and design. In this perspective, we present a few guiding…

High throughput experimentation tools, machine learning (ML) methods, and open material databases are radically changing the way new materials are discovered. From the experimentally driven approach in the past, we are moving quickly…

Materials Science · Physics 2025-08-06 Albertus Denny Handoko , Riko I Made

This article provides an introduction to and review of the field of computer-aided molecular design (CAMD). It is intended to be approachable for the absolute beginner as well as useful to the seasoned CAMD practitioner. We begin by…

Computational Engineering, Finance, and Science · Computer Science 2017-01-17 Nick D. Austin , Nikolaos V. Sahinidis , Daniel W. Trahan

Periodic material or crystal property prediction using machine learning has grown popular in recent years as it provides a computationally efficient replacement for classical simulation methods. A crucial first step for any of these…

Machine Learning · Computer Science 2024-05-08 Jonathan Balasingham , Viktor Zamaraev , Vitaliy Kurlin

Polymer-derived ceramics combine the thermal stability of ceramics with the versatile properties of carbon domains, but modeling their atomic-scale evolution during processing remains elusive due to the limitations of traditional…

A major challenge in materials design is how to efficiently search the vast chemical design space to find the materials with desired properties. One effective strategy is to develop sampling algorithms that can exploit both explicit…

Machine Learning · Computer Science 2020-06-30 Yabo Dan , Yong Zhao , Xiang Li , Shaobo Li , Ming Hu , Jianjun Hu

Machine-learning interatomic potentials (MLIPs) have greatly extended the reach of atomic-scale simulations, offering the accuracy of first-principles calculations at a fraction of the cost. Leveraging large quantum mechanical databases and…

Large-scale molecular dynamics simulations with high accuracy have been increasingly popular for their capability to bridge the gap between atomistic modeling and mesoscale phenomena. Both machine learning potentials and enhanced sampling…

Computational Physics · Physics 2026-03-24 Haoting Zhang , Qiuhan Jia , Zhennan Zhang , Yijie Zhu , Zhongwei Zhang , Junjie Wang , Jiuyang Shi , Zheyong Fan , Jian Sun

Interfaces between materials play a crucial role in the performance of most devices. However, predicting the structure of a material interface is computationally demanding due to the vast configuration space, which requires evaluating an…

Materials Science · Physics 2025-08-12 Ned Thaddeus Taylor , Joe Pitfield , Francis Huw Davies , Steven Paul Hepplestone

A new type of material with embedded intelligence, namely 'intelligent plasma', is introduced. Such new material exhibits programmable chemical pathway networks resembling artificial neural networks. As a Markov process of chemistry, the…

Emerging Technologies · Computer Science 2021-09-08 Li Lin , Michael Keidar

As the proliferation of high-throughput approaches in materials science is increasing the wealth of data in the field, the gap between accumulated-information and derived-knowledge widens. We address the issue of scientific discovery in…

The paper presents an innovative methodology based on the use of a new predictive algorithm created by the researchers capable of obtaining the elastic modulus of a plastic material manufactured with MEX and its mechanical behaviour in the…

Computational Engineering, Finance, and Science · Computer Science 2025-08-20 J. M. Mercado Colmenero , C. Martin Donate

Protein engineering is experiencing a paradigmatic shift through the integration of geometric deep learning into computational design workflows. While traditional strategies, such as rational design and directed evolution, have enabled…

The incorporation of high-performance optoelectronic devices into photonic neuromorphic processors can substantially accelerate computationally intensive operations in machine learning (ML) algorithms. However, the conventional device…

Emerging Technologies · Computer Science 2022-03-14 Yingheng Tang , Princess Tara Zamani , Ruiyang Chen , Jianzhu Ma , Minghao Qi , Cunxi Yu , Weilu Gao

To facilitate rational molecular and materials design, this research proposes an integrated computational framework that combines stochastic simulation, ab initio quantum chemistry, and molecular docking. The suggested workflow allows…

Materials Science · Physics 2026-01-08 Md Rakibul Karim Akanda , Michael P. Richard