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A fuzzy logic based classification engine has been developed for classifying mass spectra obtained with an imaging internal source Fourier transform mass spectrometer (I^2LD-FTMS). Traditionally, an operator uses the relative abundance of…

Artificial Intelligence · Computer Science 2007-05-23 Timothy R. McJunkin , Jill R. Scott

In this paper, we propose a novel weighted combination feature selection method using bootstrap and fuzzy sets. The proposed method mainly consists of three processes, including fuzzy sets generation using bootstrap, weighted combination of…

Machine Learning · Computer Science 2020-05-22 Zixiao Shen , Xin Chen , Jonathan M. Garibaldi

Breast cancer has long been a prominent cause of mortality among women. Diagnosis, therapy, and prognosis are now possible, thanks to the availability of RNA sequencing tools capable of recording gene expression data. Molecular subtyping…

Machine Learning · Computer Science 2021-11-11 Sheetal Rajpal , Virendra Kumar , Manoj Agarwal , Naveen Kumar

The application of machine learning methods to analyze changes in gene expression patterns has recently emerged as a powerful approach in cancer research, enhancing our understanding of the molecular mechanisms underpinning cancer…

Machine Learning · Computer Science 2024-09-02 Fadi Alharbi , Aleksandar Vakanski , Murtada K. Elbashir , Mohanad Mohammed

The DNA microarray technology has modernized the approach of biology research in such a way that scientists can now measure the expression levels of thousands of genes simultaneously in a single experiment. Gene expression profiles, which…

Computational Engineering, Finance, and Science · Computer Science 2011-09-07 G. Victo Sudha George , V. Cyril Raj

The identification of cancer genes is a critical yet challenging problem in cancer genomics research. Existing computational methods, including deep graph neural networks, fail to exploit the multilayered gene-gene interactions or provide…

Machine Learning · Computer Science 2023-05-04 Michail Chatzianastasis , Michalis Vazirgiannis , Zijun Zhang

Identifying the genes and mutations that drive the emergence of tumors is a major step to improve understanding of cancer and identify new directions for disease diagnosis and treatment. Despite the large volume of genomics data, the…

Machine Learning · Computer Science 2022-04-05 Renan Andrades , Mariana Recamonde-Mendoza

Accurate and early prediction of a disease allows to plan and improve a patient's quality of future life. During pandemic situations, the medical decision becomes a speed challenge in which physicians have to act fast to diagnose and…

Machine Learning · Computer Science 2022-06-09 Pierluigi Costanzo , Kalia Orphanou

DNA methylation is a well-studied genetic modification that regulates gene transcription of Eukaryotes. Its alternations have been recognized as a significant component of cancer development. In this study, we use the DNA methylation 450k…

Tissues and Organs · Quantitative Biology 2021-01-05 Shen Jia , Yulin Zhang , Yiming Mao , Jiawei Gao , Yixuan Chen , Yuxuan Jiang , Haochen Luo , Kebo Lv , Jionglong Su

Breast cancer is one of the most serious disease affecting women's health. Due to low cost, portable, no radiation, and high efficiency, breast ultrasound (BUS) imaging is the most popular approach for diagnosing early breast cancer.…

Computer Vision and Pattern Recognition · Computer Science 2019-10-24 Kuan Huang , Yingtao Zhang , H. D. Cheng , Ping Xing , Boyu Zhang

The use of machine learning (ML) for cancer staging through medical image analysis has gained substantial interest across medical disciplines. When accompanied by the innovative federated learning (FL) framework, ML techniques can further…

Machine Learning · Computer Science 2024-10-10 Kasra Borazjani , Naji Khosravan , Leslie Ying , Seyyedali Hosseinalipour

Predicting body fat can provide medical practitioners and users with essential information for preventing and diagnosing heart diseases. Hybrid machine learning models offer better performance than simple regression analysis methods by…

Neural and Evolutionary Computing · Computer Science 2025-03-10 Farshid Keivanian , Raymond Chiong , Zongwen Fan

Various approaches to gene selection for cancer classification based on microarray data can be found in the literature and they may be grouped into two categories: univariate methods and multivariate methods. Univariate methods look at each…

Quantitative Methods · Quantitative Biology 2015-06-18 Min Xu , Rudy Setiono

Segmentation of images holds an important position in the area of image processing. It becomes more important whi le typically dealing with medical images where presurgery and post surgery decisions are required for the purpose of…

Computer Vision and Pattern Recognition · Computer Science 2010-05-25 Mrigank Rajya , Sonal Rewri , Swati Sheoran

Identifying disease-associated genes enables the development of precision medicine and the understanding of biological processes. Genome-wide association studies (GWAS), gene expression data, biological pathway analysis, and protein network…

Genomics · Quantitative Biology 2026-03-10 Muhammad Muneeb , David B. Ascher , YooChan Myung

Extracting genetic information from a full range of sequencing data is important for understanding diseases. We propose a novel method to effectively explore the landscape of genetic mutations and aggregate them to predict cancer type. We…

Genomics · Quantitative Biology 2018-10-10 Zexian Zeng , Andy Vo , Chengsheng Mao , Susan E Clare , Seema A Khan , Yuan Luo

This work seeks to determine how modern machine learning techniques may be applied to the previously unexplored topic of melanoma diagnostics using digital pathology. We curated a new dataset of 50 patient cases of cutaneous melanoma using…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Adon Phillips , Iris Teo , Jochen Lang

A fuzzy expert system (FES) for the prediction of prostate cancer (PC) is prescribed in this article. Age, prostate-specific antigen (PSA), prostate volume (PV) and $\%$ Free PSA ($\%$FPSA) are fed as inputs into the FES and prostate cancer…

Quantitative Methods · Quantitative Biology 2018-12-06 Juthika Mahanta , Subhasis Panda

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

Feature selection is a vital technique in machine learning, as it can reduce computational complexity, improve model performance, and mitigate the risk of overfitting. However, the increasing complexity and dimensionality of datasets pose…

Machine Learning · Computer Science 2024-07-24 Yuepeng Chen , Weiping Ding , Hengrong Ju , Jiashuang Huang , Tao Yin