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Spectroscopic photoacoustic (sPA) imaging can potentially estimate blood oxygenation saturation (sO2) in vivo noninvasively. However, quantitatively accurate results require accurate optical fluence estimates. Robust modeling in…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Ruibo Shang , Sidhartha Jandhyala , Yujia Wu , Kevin Hoffer-Hawlik , Austin Van Namen , Matthew O'Donnell , Geoffrey P. Luke

Photoacoustic tomography (PAT) has the potential to recover morphological and functional tissue properties with high spatial resolution. However, previous attempts to solve the optical inverse problem with supervised machine learning were…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Melanie Schellenberg , Janek Gröhl , Kris K. Dreher , Jan-Hinrich Nölke , Niklas Holzwarth , Minu D. Tizabi , Alexander Seitel , Lena Maier-Hein

Significance: 2D fully convolutional neural networks have been shown capable of producing maps of sO$_2$ from 2D simulated images of simple tissue models. However, their potential to produce accurate estimates in vivo is uncertain as they…

Medical Physics · Physics 2020-05-05 Ciaran Bench , Andreas Hauptmann , Ben Cox

Estimation of blood oxygenation with spectroscopic photoacoustic imaging is a promising tool for several biomedical applications. For this method to be quantitative, it relies on an accurate method of the light fluence in the tissue. This…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Geoffrey P. Luke , Kevin Hoffer-Hawlik , Austin C. Van Namen , Ruibo Shang

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels

Purpose: Intra-operative measurement of tissue oxygen saturation (StO2) is important in the detection of ischemia, monitoring perfusion and identifying disease. Hyperspectral imaging (HSI) measures the optical reflectance spectrum of the…

Computer Vision and Pattern Recognition · Computer Science 2019-05-20 Qingbiao Li , Jianyu Lin , Neil T. Clancy , Daniel S. Elson

A major challenge in applying deep learning to medical imaging is the paucity of annotated data. This study demonstrates that synthetic colonoscopy images generated by Generative Adversarial Network (GAN) inversion can be used as training…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Mayank Golhar , Taylor L. Bobrow , Saowanee Ngamruengphong , Nicholas J. Durr

Ultrasound imaging makes use of backscattering of waves during their interaction with scatterers present in biological tissues. Simulation of synthetic ultrasound images is a challenging problem on account of inability to accurately model…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Francis Tom , Debdoot Sheet

Current methods for single-image depth estimation use training datasets with real image-depth pairs or stereo pairs, which are not easy to acquire. We propose a framework, trained on synthetic image-depth pairs and unpaired real images,…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Chuanxia Zheng , Tat-Jen Cham , Jianfei Cai

Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the…

In medical imaging, a general problem is that it is costly and time consuming to collect high quality data from healthy and diseased subjects. Generative adversarial networks (GANs) is a deep learning method that has been developed for…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Per Welander , Simon Karlsson , Anders Eklund

Artificial intelligence and machine learning techniques have the promise to revolutionize the field of digital pathology. However, these models demand considerable amounts of data, while the availability of unbiased training data is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Nati Daniel , Eliel Aknin , Ariel Larey , Yoni Peretz , Guy Sela , Yael Fisher , Yonatan Savir

Accurate measurement of optical absorption coefficients from photoacoustic imaging (PAI) data would enable direct mapping of molecular concentrations, providing vital clinical insight. The ill-posed nature of the problem of absorption…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Janek Gröhl , Thomas R. Else , Lina Hacker , Ellie V. Bunce , Paul W. Sweeney , Sarah E. Bohndiek

The difficulty in obtaining labeled data relevant to a given task is among the most common and well-known practical obstacles to applying deep learning techniques to new or even slightly modified domains. The data volumes required by the…

Computer Vision and Pattern Recognition · Computer Science 2019-09-24 Jonathan Howe , Kyle Pula , Aaron A. Reite

In the field of remote sensing, the scarcity of stereo-matched and particularly lack of accurate ground truth data often hinders the training of deep neural networks. The use of synthetically generated images as an alternative, alleviates…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Vasudha Venkatesan , Daniel Panangian , Mario Fuentes Reyes , Ksenia Bittner

In human learning, it is common to use multiple sources of information jointly. However, most existing feature learning approaches learn from only a single task. In this paper, we propose a novel multi-task deep network to learn…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Zhongzheng Ren , Yong Jae Lee

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

Significance: Photoacoustic imaging (PAI) promises to measure spatially-resolved blood oxygen saturation, but suffers from a lack of accurate and robust spectral unmixing methods to deliver on this promise. Accurate blood oxygenation…

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

Significance: Quantitative measurement of blood oxygen saturation (sO$_2$) with photoacoustic (PA) imaging is one of the most sought after goals of quantitative PA imaging research due to its wide range of biomedical applications. Aim: A…

Medical Physics · Physics 2021-02-23 Thomas Kirchner , Martin Frenz
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