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Living systems operate far from thermal equilibrium by converting the chemical potential of ATP into mechanical work to achieve growth, replication or locomotion. Given time series observations of intra-, inter- or multicellular processes,…

Biological Physics · Physics 2021-11-03 Dominic J. Skinner , Jörn Dunkel

Far-from-equilibrium thermodynamics underpins the emergence of life, but how has been a long-outstanding puzzle. Best candidate theories based on the maximum entropy production principle could not be unequivocally proven, in part due to…

Quantitative Methods · Quantitative Biology 2017-10-10 Robert G. Endres

Entropy production is a universal measure of irreversibility and energy dissipation in physical, chemical, and biological systems operating far from equilibrium. However, quantifying and spatiotemporally localising it in complex processes…

Statistical Mechanics · Physics 2026-05-18 Biswajit Das , Sreekanth K Manikandan

A major goal of stochastic thermodynamics is to estimate the inevitable dissipation that accompanies particular observable phenomena in an otherwise not fully accessible system. Quantitative results are often formulated as lower bounds on…

Statistical Mechanics · Physics 2025-03-17 Malena T. Bauer , Udo Seifert , Jann van der Meer

The thermodynamic and kinetic uncertainty relations indicate trade-offs between the relative fluctuation of observables and thermodynamic quantities such as dissipation and dynamical activity. Although these relations have been well studied…

Statistical Mechanics · Physics 2022-04-12 Tan Van Vu , Keiji Saito

The appealing theoretical measure of irreversibility in a stochastic process, as the ratio of the probabilities of a trajectory and its time reversal, cannot be accessed directly in experiment since the probability of a single trajectory is…

Statistical Mechanics · Physics 2022-04-14 Julian Kappler , Ronojoy Adhikari

The thermodynamic uncertainty relation is an inequality stating that it is impossible to attain higher precision than the bound defined by entropy production. In statistical inference theory, information inequalities assert that it is…

Statistical Mechanics · Physics 2019-06-26 Yoshihiko Hasegawa , Tan Van Vu

Entropy production (EP) is a central measure in nonequilibrium thermodynamics, as it can quantify the irreversibility of a process as well as its energy dissipation in special cases. Using the time-reversal asymmetry in a system's path…

Statistical Mechanics · Physics 2022-04-26 Dong-Kyum Kim , Sangyun Lee , Hawoong Jeong

Generalizing response theory of open systems far from equilibrium is a central quest of nonequilibrium statistical physics. Using stochastic thermodynamics, we develop an algebraic method to study the response of nonequilibrium steady state…

Statistical Mechanics · Physics 2023-08-09 Timur Aslyamov , Massimiliano Esposito

The total entropy production quantifies the extent of irreversibility in thermodynamic systems, which is nonnegative for any feasible dynamics. When additional information such as the initial and final states or moments of an observable is…

Statistical Mechanics · Physics 2020-12-29 Van Tuan Vo , Tan Van Vu , Yoshihiko Hasegawa

Stochastic thermodynamics provides the framework to analyze thermodynamic laws and quantities along individual trajectories of small but fully observable systems. If the observable level fails to capture all relevant degrees of freedom,…

Statistical Mechanics · Physics 2024-07-01 Julius Degünther , Jann van der Meer , Udo Seifert

The exploration of far-from-equilibrium systems has been at the forefront of nonequilibrium thermodynamics, with a particular focus on understanding the fluctuations and response of thermodynamic systems to external perturbations. In this…

Statistical Mechanics · Physics 2025-02-13 Kangqiao Liu , Jie Gu

In Markov networks, measurement blackouts with unknown frequency compromise observations such that thermodynamic quantities can no longer be inferred reliably. In particular, the observed currents neither discern equilibrium from…

Statistical Mechanics · Physics 2025-11-19 Alexander M. Maier , Benjamin Häsler , Udo Seifert

Entropy production (EP) is a central quantity in nonequilibrium physics as it monitors energy dissipation, irreversibility, and free energy differences during thermodynamic transformations. Estimating EP, however, is challenging both…

Statistical Mechanics · Physics 2024-06-26 Jinghao Lyu , Kyle J. Ray , James P. Crutchfield

There is a relation between the irreversibility of thermodynamic processes as expressed by the breaking of time-reversal symmetry, and the entropy production in such processes. We explain on an elementary mathematical level the relations…

Statistical Mechanics · Physics 2007-05-23 C. Maes , K. Netocny

We investigate the irreversible entropy production of a qubit in contact with an environment modelled by a microscopic collision model both in Markovian and non-Markovian regimes. Our main goal is to contribute to the discussions on the…

Quantum Physics · Physics 2022-06-15 Hüseyin T. Şenyaşa , Şahinde Kesgin , Göktuğ Karpat , Barış Çakmak

We connect two recent advances in the stochastic analysis of nonequilibrium systems: the (loose) uncertainty principle for the currents, which states that statistical errors are bounded by thermodynamic dissipation; and the analysis of…

Statistical Mechanics · Physics 2016-11-04 M. Polettini , A. Lazarescu , M. Esposito

We investigate entropy production in finitely slow transitions between nonequilibrium steady states in Markov jump processes using the improved adiabatic approximation method proposed by Takahashi, Fujii, Hino and Hayakawa [1]. This method…

Statistical Mechanics · Physics 2022-12-28 Toshihiro Matsuo , Akihiko Sonoda

In the previous papers (Kui\'{c} et al. in Found Phys 42:319-339, 2012; Kui\'{c} in arXiv:1506.02622, 2015), it was demonstrated that applying the principle of maximum information entropy by maximizing the conditional information entropy,…

Statistical Mechanics · Physics 2016-06-14 Domagoj Kuic

In the real world, one almost never knows the parameters of a thermodynamic process to infinite precision. Reflecting this, here we investigate how to extend stochastic thermodynamics to systems with uncertain parameters, including…

Statistical Mechanics · Physics 2021-03-17 Jan Korbel , David H. Wolpert