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In spite of the strong performance of machine learning (ML) models in radiology, they have not been widely accepted by radiologists, limiting clinical integration. A key reason is the lack of explainability, which ensures that model…

Human-Computer Interaction · Computer Science 2026-04-14 Sara Ketabi , Matthias W. Wagner , Birgit Betina Ertl-Wagner , Greg A. Jamieson , Farzad Khalvati

Many Machine Learning algorithms, such as deep neural networks, have long been criticized for being "black-boxes"-a kind of models unable to provide how it arrive at a decision without further efforts to interpret. This problem has raised…

Machine Learning · Statistics 2019-07-04 Yihuang Kang , I-Ling Cheng , Wenjui Mao , Bowen Kuo , Pei-Ju Lee

This study presents a comprehensive overview of PIML techniques in the context of condition monitoring. The central concept driving PIML is the incorporation of known physical laws and constraints into machine learning algorithms, enabling…

Machine Learning · Computer Science 2024-01-23 Yuandi Wu , Brett Sicard , Stephen Andrew Gadsden

The increasing size and complexity of machine learning (ML) models have driven the growing need for custom hardware accelerators capable of efficiently supporting ML workloads. However, the design of such accelerators remains a…

Machine Learning · Computer Science 2025-04-15 Raymond Baartmans , Andrew Ensinger , Victor Agostinelli , Lizhong Chen

Introducing interpretability and reasoning into Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) analysis is challenging, given the complexity of gigapixel slides. Traditionally, MIL interpretability is limited to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Saarthak Kapse , Pushpak Pati , Srijan Das , Jingwei Zhang , Chao Chen , Maria Vakalopoulou , Joel Saltz , Dimitris Samaras , Rajarsi R. Gupta , Prateek Prasanna

Physics-informed machine learning (PIML) integrates prior physical information, often in the form of differential equation constraints, into the process of fitting machine learning models to physical data. Popular PIML approaches, including…

Machine Learning · Statistics 2025-10-31 Mara Daniels , Liam Hodgkinson , Michael Mahoney

We present a physics-informed machine learning (PIML) scheme for the feedback linearization of nonlinear discrete-time dynamical systems. The PIML finds the nonlinear transformation law, thus ensuring stability via pole placement, in one…

Machine learning (ML) offers powerful methods for detecting and modeling associations often in data with large feature spaces and complex associations. Many useful tools/packages (e.g. scikit-learn) have been developed to make the various…

Machine Learning · Computer Science 2022-06-27 Ryan J. Urbanowicz , Robert Zhang , Yuhan Cui , Pranshu Suri

Local Interpretable Model-Agnostic Explanations (LIME) is a popular method to perform interpretability of any kind of Machine Learning (ML) model. It explains one ML prediction at a time, by learning a simple linear model around the…

Machine Learning · Computer Science 2022-02-09 Giorgio Visani , Enrico Bagli , Federico Chesani

DoubleML is an open-source Python library implementing the double machine learning framework of Chernozhukov et al. (2018) for a variety of causal models. It contains functionalities for valid statistical inference on causal parameters when…

Machine Learning · Statistics 2022-10-06 Philipp Bach , Victor Chernozhukov , Malte S. Kurz , Martin Spindler

In the last ten years, various automated machine learning (AutoM ) systems have been proposed to build end-to-end machine learning (ML) pipelines with minimal human interaction. Even though such automatically synthesized ML pipelines are…

Machine Learning · Computer Science 2023-11-27 Marc-André Zöller , Waldemar Titov , Thomas Schlegel , Marco F. Huber

Machine learning (ML) offers a collection of powerful approaches for detecting and modeling associations, often applied to data having a large number of features and/or complex associations. Currently, there are many tools to facilitate…

Physics-informed machine learning (PIML) represents an emerging paradigm that integrates various forms of physical knowledge into machine learning (ML) components, thereby enhancing the physical consistency of ML models compared to purely…

Chemical Physics · Physics 2025-10-28 Jiahao Wu , Xutun Wang , Guihua Zhang , Jiayue Liu , Xin Li , Yang Zhang , Hai Zhang , Junfu Lyu , Bing Wang , Yuxin Wu

Accurate temperature estimation of pouch cells with indirect liquid cooling is essential for optimizing battery thermal management systems for transportation electrification. However, it is challenging due to the computational expense of…

Machine Learning · Computer Science 2026-04-17 Zheng Liu

Summary Brain Predictability toolbox (BPt) represents a unified framework of machine learning (ML) tools designed to work with both tabulated data (in particular brain, psychiatric, behavioral, and physiological variables) and neuroimaging…

Machine Learning · Computer Science 2020-11-04 Sage Hahn , Dekang Yuan , Wesley Thompson , Max M Owens , Nicholas Allgaier , Hugh Garavan

Neural networks are widely regarded as black-box models, creating significant challenges in understanding their inner workings, especially in natural language processing (NLP) applications. To address this opacity, model explanation…

Computation and Language · Computer Science 2025-01-10 Melkamu Mersha , Mingiziem Bitewa , Tsion Abay , Jugal Kalita

Machine Learning (ML) models are often complex and difficult to interpret due to their 'black-box' characteristics. Interpretability of a ML model is usually defined as the degree to which a human can understand the cause of decisions…

Methodology · Statistics 2020-06-25 Simon Kocbek , Primoz Kocbek , Leona Cilar , Gregor Stiglic

Recent years have seen important advances in the building of interpretable models, machine learning models that are designed to be easily understood by humans. In this work, we show that large language models (LLMs) are remarkably good at…

Machine Learning · Computer Science 2024-02-23 Sebastian Bordt , Ben Lengerich , Harsha Nori , Rich Caruana

We present a novel approach to modeling the ground state mass of atomic nuclei based directly on a probabilistic neural network constrained by relevant physics. Our Physically Interpretable Machine Learning (PIML) approach incorporates…

Nuclear Theory · Physics 2022-08-17 M. R. Mumpower , T. M. Sprouse , A. E. Lovell , A. T. Mohan

High-stakes applications require AI-generated models to be interpretable. Current algorithms for the synthesis of potentially interpretable models rely on objectives or regularization terms that represent interpretability only coarsely…

Machine Learning · Computer Science 2021-04-28 Marco Virgolin , Andrea De Lorenzo , Francesca Randone , Eric Medvet , Mattias Wahde