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Flexible cognition requires the ability to rapidly detect systematic functions of variables and guide future behavior based on predictions. The model described here proposes a potential framework for patterns of neural activity to detect…

Neurons and Cognition · Quantitative Biology 2018-10-17 Michael E. Hasselmo

Edge classification, a crucial task for graph applications, remains relatively under-explored compared to link prediction. Current methods often overlook the potential causal influences of node features on edge features, leading to a loss…

Machine Learning · Computer Science 2026-05-05 Duanyu Feng , Li Ding , Hongru Liang , Wenqiang Lei

Establishing sharp and correctly positioned boundaries in spatial gene expression patterns is a central task, both in developmental and synthetic biology. We consider situations where a global morphogen gradient provides positional…

Biological Physics · Physics 2022-06-09 Mareike Bojer , Stephan Kremser , Ulrich Gerland

We introduce a new framework for manipulating and interacting with deep generative models that we call network bending. We present a comprehensive set of deterministic transformations that can be inserted as distinct layers into the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-15 Terence Broad , Frederic Fol Leymarie , Mick Grierson

A novel mechanism for cell differentiation is proposed, based on the dynamic clustering in a globally coupled chaotic system. A simple model with metabolic reaction, active transport of chemicals from media, and cell division is found to…

adap-org · Physics 2009-10-22 Kunihiko Kaneko , Tetsuya Yomo

Circuits of biological neurons, such as in the functional parts of the brain can be modeled as networks of coupled oscillators. Inspired by the ability of these systems to express a rich set of outputs while keeping (gradients of) state…

Machine Learning · Computer Science 2021-03-16 T. Konstantin Rusch , Siddhartha Mishra

A perturbative method is developed for calculating the effects of recurrent synaptic interactions between neurons embedded in a network. A series expansion is constructed that converges for networks with noisy membrane potential and weak…

Disordered Systems and Neural Networks · Physics 2009-11-10 Patrick D. Roberts

Neuroengineering is faced with unique challenges in repairing or replacing complex neural systems that are composed of many interacting parts. These interactions form intricate patterns over large spatiotemporal scales, and produce emergent…

Neurons and Cognition · Quantitative Biology 2016-12-26 Danielle S. Bassett , Ankit N. Khambhati , Scott T. Grafton

Combining additive models and neural networks allows to broaden the scope of statistical regression and extend deep learning-based approaches by interpretable structured additive predictors at the same time. Existing attempts uniting the…

Machine Learning · Statistics 2022-07-12 David Rügamer , Chris Kolb , Nadja Klein

This thesis proposes a framework based on a notion of combinatorial cell complex (cc) whose cells are defined simply as finite sets of vertices. The cells of a cc are subject to four axioms involving a rank function that assigns a rank (or…

Mathematical Physics · Physics 2022-05-03 Maxime Savoy

The increasing use of deep learning across various domains highlights the importance of understanding the decision-making processes of these black-box models. Recent research focusing on the decision boundaries of deep classifiers, relies…

Machine Learning · Computer Science 2024-08-13 Inês Gomes , Luís F. Teixeira , Jan N. van Rijn , Carlos Soares , André Restivo , Luís Cunha , Moisés Santos

The transfer matrix in lattice field theory connects the covariant and the initial data frameworks; in spin foam models, it can be written as a composition of elementary cellular amplitudes/propagators. We present a framework for discrete…

Mathematical Physics · Physics 2015-06-18 Mona Arjang , José A. Zapata

Piecewise smooth hybrid systems, involving continuous and discrete variables, are suitable models for describing the multiscale regulatory machinery of the biological cells. In hybrid models, the discrete variables can switch on and off…

Computational Engineering, Finance, and Science · Computer Science 2012-08-21 Vincent Noel , Dima Grigoriev , Sergei Vakulenko , Ovidiu Radulescu

Deep neural networks are complex and opaque. As they enter application in a variety of important and safety critical domains, users seek methods to explain their output predictions. We develop an approach to explaining deep neural networks…

Artificial Intelligence · Computer Science 2018-02-05 Michael Harradon , Jeff Druce , Brian Ruttenberg

Artificial neural networks have become important tools to harness the complexity of disordered or random photonic systems. Recent applications include the recovery of information from light that has been scrambled during propagation through…

We study a chemotaxis-consumption mechanism, in which some chemical signal and cells density interact each other. In order to control the concentration of such a population, sources involving gradient nonlinearities, which introduce a…

Analysis of PDEs · Mathematics 2025-01-24 Daniel Acosta Soba , Alessandro Columbu , Giuseppe Viglialoro

Work on deep learning-based models of grid cells suggests that grid cells generically and robustly arise from optimizing networks to path integrate, i.e., track one's spatial position by integrating self-velocity signals. In previous work,…

Neurons and Cognition · Quantitative Biology 2023-12-19 Rylan Schaeffer , Mikail Khona , Sanmi Koyejo , Ila Rani Fiete

Recurrent neural networks are powerful tools for understanding and modeling computation and representation by populations of neurons. Continuous-variable or "rate" model networks have been analyzed and applied extensively for these…

Neurons and Cognition · Quantitative Biology 2016-01-29 Brian DePasquale , Mark M. Churchland , L. F. Abbott

Complexity in the temporal organization of neural systems may be a reflection of the diversity of its neural constituents. These constituents, excitatory and inhibitory neurons, comprise an invariant ratio in vivo and form the substrate for…

Neurons and Cognition · Quantitative Biology 2015-05-18 Xin Chen , Rhonda Dzakpasu

Self-organisation of individuals within large collectives occurs throughout biology. Mathematical models can help elucidate the individual-level mechanisms behind these dynamics, but analytical tractability often comes at the cost of…