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Machine learning has demonstrated remarkable performance over finite datasets, yet whether the scores over the fixed benchmarks can sufficiently indicate the model's performance in the real world is still in discussion. In reality, an ideal…

Computer Vision and Pattern Recognition · Computer Science 2024-05-17 Peiyan Zhang , Haoyang Liu , Chaozhuo Li , Xing Xie , Sunghun Kim , Haohan Wang

Data-driven models, especially deep learning classifiers often demonstrate great success on clean datasets. Yet, they remain vulnerable to common data distortions such as adversarial and common corruption perturbations. These perturbations…

Medical Large language models achieve strong scores on standard benchmarks; however, the transfer of those results to safe and reliable performance in clinical workflows remains a challenge. This survey reframes evaluation through a…

The explainability of machine learning algorithms is crucial, and numerous methods have emerged recently. Local, post-hoc methods assign an attribution score to each feature, indicating its importance for the prediction. However, these…

Machine Learning · Computer Science 2024-08-12 Giorgio Visani , Vincenzo Stanzione , Damien Garreau

Utilizing established risk factors and prognostic models can often improve the construction of a newer risk model that uses novel biomarkers in a smaller, internal study. However, directly borrowing information from an established…

Methodology · Statistics 2026-03-12 Nicholas C. Henderson

Fine-tuning a general-purpose large language model (LLM) for a specific domain or task has become a routine procedure for ordinary users. However, fine-tuning is known to remove the safety alignment features of the model, even when the…

Computation and Language · Computer Science 2025-06-23 Kathleen C. Fraser , Hillary Dawkins , Isar Nejadgholi , Svetlana Kiritchenko

Current LLM unlearning methods face a critical security vulnerability that undermines their fundamental purpose: while they appear to successfully remove sensitive or harmful knowledge, this ``forgotten" information remains precariously…

Machine Learning · Computer Science 2025-10-01 Wenhan Wu , Zheyuan Liu , Chongyang Gao , Ren Wang , Kaize Ding

Reinforcement learning (RL) solves sequential decision-making problems via a trial-and-error process interacting with the environment. While RL achieves outstanding success in playing complex video games that allow huge trial-and-error,…

Machine Learning · Computer Science 2022-06-22 Fan-Ming Luo , Tian Xu , Hang Lai , Xiong-Hui Chen , Weinan Zhang , Yang Yu

Simulators are a pervasive tool in reinforcement learning, but most existing algorithms cannot efficiently exploit simulator access -- particularly in high-dimensional domains that require general function approximation. We explore the…

Machine Learning · Computer Science 2024-04-29 Zakaria Mhammedi , Dylan J. Foster , Alexander Rakhlin

Prompt injection attacks exploit vulnerabilities in large language models (LLMs) to manipulate the model into unintended actions or generate malicious content. As LLM integrated applications gain wider adoption, they face growing…

Cryptography and Security · Computer Science 2024-01-03 Daniel Wankit Yip , Aysan Esmradi , Chun Fai Chan

Validating Large Language Models with ReLM explores the application of formal languages to evaluate and control Large Language Models (LLMs) for memorization, bias, and zero-shot performance. Current approaches for evaluating these types…

Computation and Language · Computer Science 2025-04-18 Reece Adamson , Erin Song

With generative artificial intelligence (AI), particularly large language models (LLMs), continuing to make inroads in healthcare, it is critical to supplement traditional automated evaluations with human evaluations. Understanding and…

This paper explores the evolving relationship between clinician trust in LLMs, the transformation of data sources from predominantly human-generated to AI-generated content, and the subsequent impact on the precision of LLMs and clinician…

Computers and Society · Computer Science 2024-04-02 Avishek Choudhury , Zaria Chaudhry

The integration of artificial intelligence into clinical workflows requires reliable and robust models. Repeatability is a key attribute of model robustness. Repeatable models output predictions with low variation during independent tests…

A common practice of ML systems development concerns the training of the same model under different data sets, and the use of the same (training and test) sets for different learning models. The first case is a desirable practice for…

Logic in Computer Science · Computer Science 2025-06-06 Leonardo Ceragioli , Giuseppe Primiero

Context: An increasing demand is observed in various domains to employ Machine Learning (ML) for solving complex problems. ML models are implemented as software components and deployed in Machine Learning Software Systems (MLSSs). Problem:…

Software Engineering · Computer Science 2022-08-23 Pierre-Olivier Côté , Amin Nikanjam , Rached Bouchoucha , Foutse Khomh

Modern software systems and products increasingly rely on machine learning models to make data-driven decisions based on interactions with users, infrastructure and other systems. For broader adoption, this practice must (i) accommodate…

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

This paper presents a simple, effective, and cost-efficient strategy to improve LLM performance by scaling test-time compute. Our strategy builds upon the repeated-sampling-then-voting framework, with a novel twist: incorporating multiple…

Artificial Intelligence · Computer Science 2025-11-11 Jianhao Chen , Zishuo Xun , Bocheng Zhou , Han Qi , Hangfan Zhang , Qiaosheng Zhang , Yang Chen , Wei Hu , Yuzhong Qu , Wanli Ouyang , Shuyue Hu

Machine learning (ML) models are becoming integral in healthcare technologies, presenting a critical need for formal assurance to validate their safety, fairness, robustness, and trustworthiness. These models are inherently prone to errors,…

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