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Purpose: This work aims to develop an image reconstruction algorithm for wide-angle digital breast tomosynthesis (DBT) that has improved depth resolution and in-plane contrast while reducing non-uniformity artifacts. Approach: The image…

Optimization and Control · Mathematics 2026-05-29 Emil Y. Sidky , Adrian A. Sanchez , John Paul Phillips , Zheng Zhang , Dan Xia , Ingrid S. Reiser , Xiaochuan Pan

The detection and localization of anomalies is one important medical image analysis task. Most commonly, Computer Vision anomaly detection approaches rely on manual annotations that are both time consuming and expensive to obtain.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Sergio Naval Marimont , Giacomo Tarroni

Automatic detection of visual anomalies and changes in the environment has been a topic of recurrent attention in the fields of machine learning and computer vision over the past decades. A visual anomaly or change detection algorithm…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Sahar Salimpour , Jorge Peña Queralta , Tomi Westerlund

Image manipulation detection algorithms designed to identify local anomalies often rely on the manipulated regions being ``sufficiently'' different from the rest of the non-tampered regions in the image. However, such anomalies might not be…

Computer Vision and Pattern Recognition · Computer Science 2023-04-20 Rosaura G. VidalMata , Priscila Saboia , Daniel Moreira , Grant Jensen , Jason Schlessman , Walter J. Scheirer

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

We aim to investigate the impact of image and signal properties on visual attention mechanisms during a signal detection task in digital images. The application of insight yielded from this work spans many areas of digital imaging where…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Amar Kavuri , Howard C. Gifford , Mini Das

In recent years, convolutional neural networks for semantic segmentation of breast ultrasound (BUS) images have shown great success; however, two major challenges still exist. 1) Most current approaches inherently lack the ability to…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Kyle Lucke , Aleksandar Vakanski , Min Xian

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

Digital breast tomosynthesis (DBT) exams should utilize the lowest possible radiation dose while maintaining sufficiently good image quality for accurate medical diagnosis. In this work, we propose a convolution neural network (CNN) to…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Rodrigo de Barros Vimieiro , Chuang Niu , Hongming Shan , Lucas Rodrigues Borges , Ge Wang , Marcelo Andrade da Costa Vieira

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

In this paper, we would like to quantitatively measure the tumor volume contained in the breast imaged by the Digital Breast Tomosynthesis (DBT), a reconstructed 3D image. The estimated volume will add to the prognostic value of risk…

Medical Physics · Physics 2018-04-17 Bocar Wane

Data transformations (e.g. rotations, reflections, and cropping) play an important role in self-supervised learning. Typically, images are transformed into different views, and neural networks trained on tasks involving these views produce…

Machine Learning · Computer Science 2022-02-04 Chen Qiu , Timo Pfrommer , Marius Kloft , Stephan Mandt , Maja Rudolph

Objective: In this work, we perform margin assessment of human breast tissue from optical coherence tomography (OCT) images using deep neural networks (DNNs). This work simulates an intraoperative setting for breast cancer lumpectomy.…

Detecting anomalies in brain MRI scans using supervised deep learning methods presents challenges due to anatomical diversity and labor-intensive requirement of pixel-level annotations. Generative models like Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Vivek Kumar Trivedi , Bheeshm Sharma , P. Balamurugan

This review explores anomaly localization in medical images using denoising diffusion models. After providing a brief methodological background of these models, including their application to image reconstruction and their conditioning…

Image and Video Processing · Electrical Eng. & Systems 2025-12-15 Cosmin I. Bercea , Philippe C. Cattin , Julia A. Schnabel , Julia Wolleb

This paper considers the real-time detection of anomalies in high-dimensional systems. The goal is to detect anomalies quickly and accurately so that the appropriate countermeasures could be taken in time, before the system possibly gets…

Machine Learning · Computer Science 2020-07-16 Mahsa Mozaffari , Yasin Yilmaz

This article provides a thorough meta-analysis of the anomaly detection problem. To accomplish this we first identify approaches to benchmarking anomaly detection algorithms across the literature and produce a large corpus of anomaly…

Artificial Intelligence · Computer Science 2016-08-29 Andrew Emmott , Shubhomoy Das , Thomas Dietterich , Alan Fern , Weng-Keen Wong

Most unsupervised image anomaly localization methods suffer from overgeneralization because of the high generalization abilities of convolutional neural networks, leading to unreliable predictions. To mitigate the overgeneralization, this…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Yunkang Cao , Xiaohao Xu , Zhaoge Liu , Weiming Shen

We investigate unsupervised anomaly detection for high-dimensional data and introduce a deep metric learning (DML) based framework. In particular, we learn a distance metric through a deep neural network. Through this metric, we project the…

Machine Learning · Computer Science 2020-05-13 Selim F. Yilmaz , Suleyman S. Kozat

Deep learning has now become the de facto approach to the recognition of anomalies in medical imaging. Their 'black box' way of classifying medical images into anomaly labels poses problems for their acceptance, particularly with…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Satyananda Kashyap , Alexandros Karargyris , Joy Wu , Yaniv Gur , Arjun Sharma , Ken C. L. Wong , Mehdi Moradi , Tanveer Syeda-Mahmood