Related papers: Cellular blood flow modelling with HemoCell
Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…
While experiments and computer simulations to study biological phenomena are usually performed in diluted in vitro conditions, such phenomena happen inside the cell, an environment densely packed with diverse macromolecules. Here, we revise…
Red blood cells (RBCs) are vital for transporting oxygen from the lungs to the body's tissues through the intricate circulatory system. They achieve this by binding and releasing oxygen molecules to the abundant hemoglobin within their…
Multicellular systems play a key role in bioprocess and biomedical engineering. Cell ensembles encountered in these setups show phenotypic variability like size and biochemical composition. As this variability may result in undesired…
Cell motility in viscous fluids is ubiquitous and affects many biological processes, including reproduction, infection, and the marine life ecosystem. Here we review the biophysical and mechanical principles of locomotion at the small…
A bio-heat transfer model for biological tissues in a micro-scale and periodical settings is investigated . It is assumed that the model is a two-component system consisting of solid particles representing tissue cells and interconnected…
A simple model accounting for the ejection of heavy particles from the vortical structures of a turbulent flow is introduced. This model involves a space and time discretization of the dynamics and depends on only two parameters: the…
Understanding how red blood cell (RBC) suspensions navigate porous materials is critical for for both fundamental physiology, such as maternal-fetal exchange in the placenta, and transformative biomedical applications, including rapid,…
The liver has a unique blood supply system and plays an important role in the human blood circulatory system. Thus, hemodynamic problems related to the liver serve as an important part in clinical diagnosis and treatment. Although…
We reveal that under moderate shear stress (of the order of 0.1 Pa) red blood cells present an oscillation of their inclination (swinging) superimposed to the long-observed steady tanktreading (TT) motion. A model based on a fluid ellipsoid…
Integrating optical diffraction tomography with imaging flow cytometry enables label-free quantifications of the three-dimensional (3D) morphology and hemoglobin content of red blood cells (RBCs) in their natural form. Self-rotation of RBCs…
Self-regulation of living tissue as an example of self-organization phenomena in active fractal systems of biological, ecological, and social nature is under consideration. The characteristic feature of these systems is the absence of any…
The analysis of non-equilibrium steady states of biochemical reaction networks relies on finding the configurations of fluxes and chemical potentials satisfying stoichiometric (mass balance) and thermodynamic (energy balance) constraints.…
Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…
Exact values for bulk and shear viscosity are important to characterize a fluid and they are a necessary input for a continuum description. Here we present two novel methods to compute bulk viscosities by non-equilibrium molecular dynamics…
A noteworthy aspect in blood flow modeling is the definition of the mechanical interaction between the fluid flow and the biological structure that contains it, namely the vessel wall. It has been demonstrated that the addition of a viscous…
Numerical simulations of pulsatile blood flow in an aortic coarctation require the use of turbulence modeling. This paper considers three models from the class of large eddy simulation (LES) models (Smagorinsky, Vreman,…
Numerical simulations of real-world phenomena require a computational scheme and a computational domain. In the context of haemodynamics, the computational domain is the blood vessel network through which blood flows. Such networks contain…
This work deals with the evaluation of the flow curve of colloidal systems that develop fluid phases with different mechanical properties, namely shear-banding fluids. The problem involved is that, as different fluid phases coexist in the…
Application of computation in many fields are growing fast in last two decades. Increasing on computation performance helps researchers to understand natural phenomena in many fields of science and technology including in life sciences.…