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Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

Machine learning models that learn from dynamic graphs face nontrivial challenges in learning and inference as both nodes and edges change over time. The existing large-scale graph benchmark datasets that are widely used by the community…

Adoption of recently developed methods from machine learning has given rise to creation of drug-discovery knowledge graphs (KG) that utilize the interconnected nature of the domain. Graph-based modelling of the data, combined with KG…

Machine Learning · Computer Science 2022-07-27 Stephen Bonner , Ufuk Kirik , Ola Engkvist , Jian Tang , Ian P Barrett

Distributed representations of medical concepts have been used to support downstream clinical tasks recently. Electronic Health Records (EHR) capture different aspects of patients' hospital encounters and serve as a rich source for…

Computation and Language · Computer Science 2020-01-07 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Peptide therapeutics are widely regarded as the "third generation" of drugs, yet progress in peptide Machine Learning (ML) are hindered by the absence of standardized benchmarks. Here we present PepBenchmark, which unifies datasets,…

Machine Learning · Computer Science 2026-04-14 Jiahui Zhang , Rouyi Wang , Kuangqi Zhou , Tianshu Xiao , Lingyan Zhu , Yaosen Min , Yang Wang

Recent years have witnessed the emerging success of graph neural networks (GNNs) for modeling structured data. However, most GNNs are designed for homogeneous graphs, in which all nodes and edges belong to the same types, making them…

Machine Learning · Computer Science 2020-03-04 Ziniu Hu , Yuxiao Dong , Kuansan Wang , Yizhou Sun

The diagnosis and prognosis of cancer are typically based on multi-modal clinical data, including histology images and genomic data, due to the complex pathogenesis and high heterogeneity. Despite the advancements in digital pathology and…

Quantitative Methods · Quantitative Biology 2024-04-15 Zeyu Zhang , Yuanshen Zhao , Jingxian Duan , Yaou Liu , Hairong Zheng , Dong Liang , Zhenyu Zhang , Zhi-Cheng Li

Recently, real-world recommendation systems need to deal with millions of candidates. It is extremely challenging to conduct sophisticated end-to-end algorithms on the entire corpus due to the tremendous computation costs. Therefore,…

Information Retrieval · Computer Science 2021-10-15 Ruobing Xie , Qi Liu , Shukai Liu , Ziwei Zhang , Peng Cui , Bo Zhang , Leyu Lin

Given an input graph G and a node v in G, homogeneous network embedding (HNE) maps the graph structure in the vicinity of v to a compact, fixed-dimensional feature vector. This paper focuses on HNE for massive graphs, e.g., with billions of…

Social and Information Networks · Computer Science 2020-06-24 Renchi Yang , Jieming Shi , Xiaokui Xiao , Yin Yang , Sourav S. Bhowmick

Label errors have been found to be prevalent in popular text, vision, and audio datasets, which heavily influence the safe development and evaluation of machine learning algorithms. Despite increasing efforts towards improving the quality…

Machine Learning · Computer Science 2023-06-02 Yuwen Li , Miao Xiong , Bryan Hooi

Heterogeneous Text-Attributed Graphs (HTAGs), where different types of entities are not only associated with texts but also connected by diverse relationships, have gained widespread popularity and application across various domains.…

Machine Learning · Computer Science 2024-12-13 Yunhui Liu , Qizhuo Xie , Jinwei Shi , Jiaxu Shen , Tieke He

Handling heterogeneous data in tabular datasets poses a significant challenge for deep learning models. While attention-based architectures and self-supervised learning have achieved notable success, their application to tabular data…

Machine Learning · Computer Science 2025-02-27 Anay Majee , Maria Xenochristou , Wei-Peng Chen

Predicting drug-gene associations is crucial for drug development and disease treatment. While graph neural networks (GNN) have shown effectiveness in this task, they face challenges with data sparsity and efficient contrastive learning…

Machine Learning · Computer Science 2025-02-14 Jiayang Wu , Wensheng Gan , Philip S. Yu

Heterogeneous graphs are ubiquitous in real-world applications because they can represent various relationships between different types of entities. Therefore, learning embeddings in such graphs is a critical problem in graph machine…

Machine Learning · Computer Science 2024-04-02 Yue Zhang , Yuntian He , Saket Gurukar , Srinivasan Parthasarathy

Heterogeneous molecular entities and their interactions, commonly depicted as a network, are crucial for advancing our systems-level understanding of biology. With recent advancements in high-throughput data generation and a significant…

Quantitative Methods · Quantitative Biology 2026-03-18 Kishan KC , Rui Li , Paribesh Regmi , Anne R. Haake

Since real-world objects and their interactions are often multi-modal and multi-typed, heterogeneous networks have been widely used as a more powerful, realistic, and generic superclass of traditional homogeneous networks (graphs).…

Social and Information Networks · Computer Science 2020-12-18 Carl Yang , Yuxin Xiao , Yu Zhang , Yizhou Sun , Jiawei Han

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Graph Neural Networks (GNNs) are characterized by their capacity of processing graph-structured data. However, due to the sparsity of labels under semi-supervised learning, they have been found to exhibit biased performance on specific…

Machine Learning · Computer Science 2025-12-16 Yihan Zhang

Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and…

Currently, most people use PubMed to search the MEDLINE database, an important bibliographical information source for life science and biomedical information. However, PubMed has some drawbacks that make it difficult to find relevant…

Information Retrieval · Computer Science 2015-09-01 James Z. Wang , Yuanyuan Zhang , Liang Dong , Lin Li , Pradip K Srimani , Philip S. Yu
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