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Although prediction models for delirium, a commonly occurring condition during general hospitalization or post-surgery, have not gained huge popularity, their algorithmic bias evaluation is crucial due to the existing association between…

Machine Learning · Computer Science 2022-11-29 Sandhya Tripathi , Bradley A Fritz , Michael S Avidan , Yixin Chen , Christopher R King

We seek to elucidate the impact of social activity, physical activity and functional health status (factors) on depressive symptoms (outcome) in the China Health and Retirement Longitudinal Study (CHARLS), a multi-year study of aging…

Applications · Statistics 2019-12-06 Yazhuo Deng , David R. Paul , Audrey Q. Fu

Growing evidence suggests that social determinants of health (SDoH), a set of nonmedical factors, affect individuals' risks of developing Alzheimer's disease (AD) and related dementias. Nevertheless, the etiological mechanisms underlying…

Artificial Intelligence · Computer Science 2025-04-17 Tianqi Shang , Shu Yang , Weiqing He , Tianhua Zhai , Dawei Li , Bojian Hou , Tianlong Chen , Jason H. Moore , Marylyn D. Ritchie , Li Shen

Dementia in the elderly has recently become the most usual cause of cognitive decline. The proliferation of dementia cases in aging societies creates a remarkable economic as well as medical problems in many communities worldwide. A…

Neurons and Cognition · Quantitative Biology 2019-06-20 Tomasz M. Rutkowski , Marcin Koculak , Masato S. Abe , Mihoko Otake-Matsuura

As artificial intelligence (AI) continues to advance, understanding public perceptions -- including biases, risks, and benefits -- is essential for guiding research priorities and AI alignment, shaping public discourse, and informing…

Computers and Society · Computer Science 2025-08-27 Philipp Brauner , Felix Glawe , Gian Luca Liehner , Luisa Vervier , Martina Ziefle

Delirium represents a significant clinical concern characterized by high morbidity and mortality rates, particularly in patients with mild cognitive impairment (MCI). This study investigates the associated risk factors for delirium by…

Cross-sectional age-skill profiles suggest that workers' cognitive skills start declining by their thirties if not earlier. If accurate, such age-driven skill losses pose a major threat to the human capital of societies with rapidly aging…

General Economics · Economics 2025-05-08 Eric A. Hanushek , Lavinia Kinne , Frauke Witthoeft , Ludger Woessmann

According to the World Health Organization, the rate of people aged 60 or more is growing faster than any other age group in almost every country, and this trend is not going to change in a near future. Since senior citizens are at high…

Other Computer Science · Computer Science 2015-01-23 Daniele Riboni , Claudio Bettini , Gabriele Civitarese , Zaffar Haider Janjua , Rim Helaoui

Despite the great promise that machine learning has offered in many fields of medicine, it has also raised concerns about potential biases and poor generalization across genders, age distributions, races and ethnicities, hospitals, and data…

Machine Learning · Computer Science 2023-02-01 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…

Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clinical applications, and casting doubt on the generalisability…

Neurons and Cognition · Quantitative Biology 2024-04-04 James K Ruffle , Robert J Gray , Samia Mohinta , Guilherme Pombo , Chaitanya Kaul , Harpreet Hyare , Geraint Rees , Parashkev Nachev

Disorders of consciousness are a heterogeneous mixture of different diseases or injuries. Although some indicators and models have been proposed for prognostication, any single method when used alone carries a high risk of false prediction.…

Neurons and Cognition · Quantitative Biology 2018-09-10 Ming Song , Yi Yang , Jianghong He , Zhengyi Yang , Shan Yu , Qiuyou Xie , Xiaoyu Xia , Yuanyuan Dang , Qiang Zhang , Xinhuai Wu , Yue Cui , Bing Hou , Ronghao Yu , Ruxiang Xu , Tianzi Jiang

Background: Invasive coronary arteriography (ICA) is recognized as the gold standard for diagnosing cardiovascular diseases, including unstable angina (UA). The challenge lies in determining the optimal timing for ICA in UA patients,…

Machine Learning · Computer Science 2024-08-09 Candi Zheng , Kun Liu , Yang Wang , Shiyi Chen , Hongli Li

Every year in the United States, 800,000 individuals suffer a stroke - one person every 40 seconds, with a death occurring every four minutes. While individual factors vary, certain predictors are more prevalent in determining stroke risk.…

Machine Learning · Computer Science 2025-01-03 Aidan Chadha

Conversational speech often reveals early signs of cognitive decline, such as dementia and MCI. In the UK, one in four people belongs to an ethnic minority, and dementia prevalence is expected to rise most rapidly among Black and Asian…

Computation and Language · Computer Science 2026-02-16 Madhurananda Pahar , Caitlin Illingworth , Dorota Braun , Bahman Mirheidari , Lise Sproson , Daniel Blackburn , Heidi Christensen

The prevalence of suicide has been on the rise since the 20th century, causing severe emotional damage to individuals, families, and communities alike. Despite the severity of this suicide epidemic, there is so far no reliable and…

Signal Processing · Electrical Eng. & Systems 2022-06-16 Siyu Liu , Catherine Lu , Sharifa Alghowinem , Lea Gotoh , Cynthia Breazeal , Hae Won Park

Analysis of child mortality is crucial as it pertains to the policy and programs of a country. The early assessment of patterns and trends in causes of child mortality help decision-makers assess needs, prioritize interventions, and monitor…

Computers and Society · Computer Science 2020-11-20 Asadullah Hill Galib , Nadia Nahar , B M Mainul Hossain

Deep learning has been shown to accurately assess 'hidden' phenotypes and predict biomarkers from medical imaging beyond traditional clinician interpretation of medical imaging. Given the black box nature of artificial intelligence (AI)…

Machine Learning · Computer Science 2023-08-31 Grant Duffy , Shoa L. Clarke , Matthew Christensen , Bryan He , Neal Yuan , Susan Cheng , David Ouyang

Prior to clinical applications, it is critical that risk prediction models are evaluated in independent studies that did not contribute to model development. While prospective cohort studies provide a natural setting for model validation,…

Methodology · Statistics 2017-10-13 Parichoy Pal Choudhury , Anil K. Chaturvedi , Nilanjan Chatterjee

Early dementia diagnosis requires biomarkers sensitive to both structural and functional brain changes. While structural neuroimaging biomarkers have progressed significantly, objective functional biomarkers of early cognitive decline…

Neurons and Cognition · Quantitative Biology 2025-04-16 Tomasz M. Rutkowski , Stanisław Narębski , Mihoko Otake-Matsuura , Tomasz Komendziński