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We present a continuum level analytical model of a droplet of active contractile fluid consisting of filaments and motors. We calculate the steady state flows that result from a splayed polarisation of the filaments. We account for the…

Cell Behavior · Quantitative Biology 2014-02-20 Carl A. Whitfield , Davide Marenduzzo , Raphaël Voituriez , Rhoda J. Hawkins

This paper considers membranes of globular structure in the framework of the cell model technique. Coupled micropolar and Brinkman-type equations are used to model the flow of micropolar fluid through a spherical cell, consisting of solid…

Fluid Dynamics · Physics 2020-05-05 D. Yu. Khanukaeva

The non-linear response of entangled polymers to shear flow is complicated. Its current understanding is framed mainly as a rheological description in terms of the complex viscosity. However, the full picture requires an assessment of the…

Computational Physics · Physics 2018-08-21 Airidas Korolkovas , Philipp Gutfreund , Max Wolff

Most computer simulations of molecular dynamics take place under equilibrium conditions--in a closed, isolated system, or perhaps one held at constant temperature or pressure. Sometimes, extra tensions, shears, or temperature gradients are…

Statistical Mechanics · Physics 2022-05-25 Alex Albaugh , Todd R. Gingrich

Active processes drive and guide biological dynamics across scales -- from subcellular cytoskeletal remodelling, through tissue development in embryogenesis, to population-level bacterial colonies expansion. In each of these, biological…

The dynamics of a heteropolymer chain in solution is studied in the limit of long chain length. Using functional integral representation we derive an effective equation of motion, in which the heterogeneity of the chain manifests itself as…

Condensed Matter · Physics 2009-10-28 Jiunn-Ren Roan , E. I. Shakhnovich

Loop extrusion by motor proteins mediates the attractive interactions in chromatin on the length scale of megabases, providing the polymer with a well-defined structure and at the same time determining its dynamics. The mean square…

Biomolecules · Quantitative Biology 2023-07-12 E. Marchi , Y. Zhan , G. Tiana

We study the flow of a shear-thinning, chemically-reacting fluid that could be used to model the flow of the synovial fluid. The actual geometry where the flow of the synovial fluid takes place is very complicated, and therefore the…

Numerical Analysis · Computer Science 2014-09-01 Craig Bridges , Satish Karra , K. R. Rajagopal

While the structure of chromatin has been studied in great detail on length scales below 30 nm, amazingly little is known about the higher-order folding motifs of chromatin in interphase. Recent experiments give evidence that the folding…

Soft Condensed Matter · Physics 2009-02-16 Manfred Bohn , Dieter W. Heermann , Roel van Driel

Polymers are a primary building block in many biomaterials, often interacting with anisotropic backgrounds. While previous studies have considered polymer dynamics within nematic solvents, rarely are the the effects of anisotropic viscosity…

Motivated by the motion of biopolymers and membranes in solution, this article presents a formulation of the equations of motion for curves and surfaces in a viscous fluid. We focus on geometrical aspects and simple variational methods for…

Soft Condensed Matter · Physics 2010-05-26 Thomas R. Powers

We have developed a simulation model to study the hydrodynamic flow fields around Brownian colloidal particles with an active surface patch. Hydrodynamics is introduced by modeling low-Reynolds-number fluid flows around a colloid using…

Star polymers can exhibit a heterogeneous dynamical behavior due to their internal structure. In this work we employ atomistic molecular dynamics simulations to study translational motion in non-entangled polystyrene and poly(ethylene…

Soft Condensed Matter · Physics 2021-02-03 Petra Bačová , Eirini Gkolfi , Laurence G. D. Hawke , Vagelis Harmandaris

The structure and dynamics of confined suspensions of particles of arbitrary shape is of interest in multiple disciplines, from biology to engineering. Theoretical studies are often limited by the complexity of long-range particle-particle…

We derive the Hydrodynamics for a system of N active, spherical, underdamped particles, interacting through conservative forces. At the microscopic level, we represent the evolution of the particles in terms of the Kramers equation for the…

Statistical Mechanics · Physics 2022-03-15 Umberto Marini Bettolo Marconi , Andrea Puglisi , Lorenzo Caprini

We study the dynamics of an ideal polymer chain in a crowded, viscoelastic medium and in the presence of active forces. The motion of the centre of mass and of individual monomers is calculated. On time scales that are comparable to the…

Soft Condensed Matter · Physics 2015-12-23 Hans Vandebroek , Carlo Vanderzande

We use linear stability analysis and hybrid lattice Boltzmann simulations to study the dynamical behaviour of an active nematic confined in a channel made of viscoelastic material. We find that the quiescent, ordered active nematic is…

Soft Condensed Matter · Physics 2023-12-20 Francesco Mori , Saraswat Bhattacharyya , Julia M. Yeomans , Sumesh P. Thampi

The actin cytoskeleton of cells is in continuous motion due to both polymerization of new filaments and their contraction by myosin II molecular motors. Through adhesion to the substrate, such intracellular flow can be converted into cell…

Subcellular Processes · Quantitative Biology 2021-08-11 Oliver M. Drozdowski , Falko Ziebert , Ulrich S. Schwarz

Strongly confined active liquids are subject to unique hydrodynamic interactions due to momentum screening and lubricated friction by the confining walls. Using numerical simulations, we demonstrate that 2D dilute suspensions of fore-aft…

Soft Condensed Matter · Physics 2015-06-16 Adrien Lefauve , David Saintillan

While the dynamics of polymer chains in equilibrium media is well understood by now, the polymer dynamics in active non-equilibrium environments can be very different. Here we study the dynamics of polymers in a viscous medium containing…

Soft Condensed Matter · Physics 2017-06-23 Jaeoh Shin , Andrey G. Cherstvy , Won Kyu Kim , Vasily Zaburdaev
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