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Domain generalization (DG) aims to enhance the model robustness against domain shifts without accessing target domains. A prevalent category of methods for DG is data augmentation, which focuses on generating virtual samples to simulate…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Jintao Guo , Lei Qi , Yinghuan Shi , Yang Gao

Due to domain shifts across diverse medical imaging modalities, learned segmentation models often suffer significant performance degradation during deployment. We posit that these domain shifts can generally be categorized into two main…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane , Zhaolin Chen

State-of-the-art stereo matching (SM) models trained on synthetic data often fail to generalize to real data domains due to domain differences, such as color, illumination, contrast, and texture. To address this challenge, we leverage data…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Shuangli Du , Jing Wang , Minghua Zhao , Zhenyu Xu , Jie Li

The generalization with respect to domain shifts, as they frequently appear in applications such as autonomous driving, is one of the remaining big challenges for deep learning models. Therefore, we propose an intra-source style…

Computer Vision and Pattern Recognition · Computer Science 2023-05-30 Yumeng Li , Dan Zhang , Margret Keuper , Anna Khoreva

3D object detection is crucial for applications like autonomous driving and robotics. However, in real-world environments, variations in sensor data distribution due to sensor upgrades, weather changes, and geographic differences can…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Yecheol Kim , Junho Lee , Changsoo Park , Hyoung won Kim , Inho Lim , Christopher Chang , Jun Won Choi

Test-time adaptation (TTA) aims to improve the performance of source-domain pre-trained models on previously unseen, shifted target domains. Traditional TTA methods primarily adapt model weights based on target data streams, making model…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Jiayi Guo , Junhao Zhao , Chaoqun Du , Yulin Wang , Chunjiang Ge , Zanlin Ni , Shiji Song , Humphrey Shi , Gao Huang

Single-source domain generalization (SDG) in medical image segmentation is a challenging yet essential task as domain shifts are quite common among clinical image datasets. Previous attempts most conduct global-only/random augmentation.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Zixian Su , Kai Yao , Xi Yang , Qiufeng Wang , Jie Sun , Kaizhu Huang

Point-cloud-based 3D object detection suffers from performance degradation when encountering data with novel domain gaps. To tackle it, the single-domain generalization (SDG) aims to generalize the detection model trained in a limited…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Shuangzhi Li , Lei Ma , Xingyu Li

Synthetically augmenting training datasets with diffusion models has become an effective strategy for improving the generalization of image classifiers. However, existing approaches typically increase dataset size by 10-30x and struggle to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Dang Nguyen , Jiping Li , Jinghao Zheng , Baharan Mirzasoleiman

Despite notable advancements, the integration of deep learning (DL) techniques into impactful clinical applications, particularly in the realm of digital histopathology, has been hindered by challenges associated with achieving robust…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Sebastian Doerrich , Francesco Di Salvo , Christian Ledig

Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, in clinically realistic environments, such methods have marginal performance due to differences in image domains, including…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Ling Zhang , Xiaosong Wang , Dong Yang , Thomas Sanford , Stephanie Harmon , Baris Turkbey , Holger Roth , Andriy Myronenko , Daguang Xu , Ziyue Xu

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

The problem of adapting models from a source domain using data from any target domain of interest has gained prominence, thanks to the brittle generalization in deep neural networks. While several test-time adaptation techniques have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Rakshith Subramanyam , Kowshik Thopalli , Spring Berman , Pavan Turaga , Jayaraman J. Thiagarajan

High Content Imaging (HCI) plays a vital role in modern drug discovery and development pipelines, facilitating various stages from hit identification to candidate drug characterization. Applying machine learning models to these datasets can…

Computer Vision and Pattern Recognition · Computer Science 2023-11-22 Johan Fredin Haslum , Christos Matsoukas , Karl-Johan Leuchowius , Kevin Smith

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

Deep learning models in medical image analysis often struggle with generalizability across domains and demographic groups due to data heterogeneity and scarcity. Traditional augmentation improves robustness, but fails under substantial…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Sebastian Doerrich , Francesco Di Salvo , Jonas Alle , Christian Ledig

Unsupervised Domain Adaptation (UDA) and domain generalization (DG) are two research areas that aim to tackle the lack of generalization of Deep Neural Networks (DNNs) towards unseen domains. While UDA methods have access to unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2023-04-25 Manuel Schwonberg , Fadoua El Bouazati , Nico M. Schmidt , Hanno Gottschalk

Stain variations often decrease the generalization ability of deep learning based approaches in digital histopathology analysis. Two separate proposals, namely stain normalization (SN) and stain augmentation (SA), have been spotlighted to…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Yiqing Shen , Yulin Luo , Dinggang Shen , Jing Ke

Deep models often suffer significant performance degradation under distribution shifts. Domain generalization (DG) seeks to mitigate this challenge by enabling models to generalize to unseen domains. Most prior approaches rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Zhicheng Lin , Xiaolin Wu , Xi Zhang

In AI-based histopathology, domain shifts are common and well-studied. However, this research focuses on stain and scanner variations, which do not show the full picture -- shifts may be combinations of other shifts, or "invisible" shifts…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 Andrew Walker
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