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Functional connectivity (FC) has been widely used to study brain network interactions underlying the emerging cognition and behavior of an individual. FC is usually defined as the correlation or partial correlation between brain regions.…

Applications · Statistics 2020-10-27 Gemeng Zhang , Aiying Zhang , Biao Cai , Zhuozhuo Tu , Vince D. Calhoun , Yu-Ping Wang

The available evidence suggests that dynamic functional connectivity (dFC) can capture time-varying abnormalities in brain activity in resting-state cerebral functional magnetic resonance imaging (rs-fMRI) data and has a natural advantage…

Neurons and Cognition · Quantitative Biology 2023-09-13 Cheng Zhu , Ying Tan , Shuqi Yang , Jiaqing Miao , Jiayi Zhu , Huan Huang , Dezhong Yao , Cheng Luo

Clinical studies reveal disruptions in brain structural connectivity (SC) and functional connectivity (FC) in neuropsychiatric disorders such as schizophrenia (SZ). Traditional approaches might rely solely on SC due to limited functional…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Badhan Mazumder , Ayush Kanyal , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Objective: Multimodal measurements of the same phenomena provide complementary information and highlight different perspectives, albeit each with their own limitations. A focus on a single modality may lead to incorrect inferences, which is…

Modularity plays an important role in brain networks' architecture and influences its dynamics and the ability to integrate and segregate different modules of cerebral regions. Alterations in community structure are associated with several…

Neurons and Cognition · Quantitative Biology 2018-05-14 M. Cinelli , I. Echegoyen , M. Oliveira , S. Orellana , T. Gili

Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

Neurons and Cognition · Quantitative Biology 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

Network neuroscience shed some light on the functional and structural modifications occurring to the brain associated with the phenomenology of schizophrenia. In particular, resting-state functional networks have helped our understanding of…

Neurons and Cognition · Quantitative Biology 2021-04-30 Rossana Mastrandrea , Fabrizio Piras , Andrea Gabrielli , Nerisa Banaj , Guido Caldarelli , Gianfranco Spalletta , Tommaso Gili

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

Neurons and Cognition · Quantitative Biology 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

First-episode schizophrenia (FES) results in abnormality of brain connectivity at different levels. Despite some successful findings on functional and structural connectivity of FES, relatively few studies have been focused on morphological…

Neurons and Cognition · Quantitative Biology 2022-12-27 Mowen Yin , Weikai Huang , Zhichao Liang , Quanying Liu , Xiaoying Tang

Schizophrenia is a serious psychiatric disorder. Its pathogenesis is not completely clear, making it difficult to treat patients precisely. Because of the complicated non-Euclidean network structure of the human brain, learning critical…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Yuhong Jiao , Jiaqing Miao , Jinnan Gong , Hui He , Ping Liang , Cheng Luo , Ying Tan

In spite of years of research, the mechanisms that underlie the development of schizophrenia, as well as its relapse, symptomatology, and treatment, continue to be a mystery. The absence of appropriate analytic tools to deal with the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Vigneshwaran Shankaran , Bhaskaran V

Schizophrenia is a debilitating, chronic mental disorder that significantly impacts an individual's cognitive abilities, behavior, and social interactions. It is characterized by subtle morphological changes in the brain, particularly in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Nagur Shareef Shaik , Teja Krishna Cherukuri , Vince Calhoun , Dong Hye Ye

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both…

Neurons and Cognition · Quantitative Biology 2026-04-14 Nicolas Rubido , Venia Batziou , Marwan Fuad , Vesna Vuksanovic

In the field of neuroscience, Brain activity analysis is always considered as an important area. Schizophrenia(Sz) is a brain disorder that severely affects the thinking, behaviour, and feelings of people all around the world.…

Signal Processing · Electrical Eng. & Systems 2021-11-23 Geetanjali Sharma , Amit M. Joshi

Dynamic functional connectivity (dFC) derived from resting-state functional magnetic resonance imaging (fMRI) has been extensively utilized in brain science research. The sliding window correlation (SWC) method is a widely used approach for…

Neurons and Cognition · Quantitative Biology 2026-03-27 Jinlong Hu , Jiatong Huang , Zijian Cai

We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently…

Machine Learning · Computer Science 2020-04-27 Chun-Ren Phang , Chee-Ming Ting , Fuad Noman , Hernando Ombao

Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Junhao Zhang , Vishwanatha M. Rao , Ye Tian , Yanting Yang , Nicolas Acosta , Zihan Wan , Pin-Yu Lee , Chloe Zhang , Lawrence S. Kegeles , Scott A. Small , Jia Guo

Schizophrenia (SCZ), as a chronic and persistent disorder, exhibits working memory deficits across various stages of the disorder, yet the neural mechanisms underlying these deficits remain elusive with inconsistent neuroimaging findings.…

Neurons and Cognition · Quantitative Biology 2023-10-16 Yuhao Yao , Shufang Zhang , Boyao Wang , Gaofeng Zhao , Hong Deng , Ying Chen

Schizophrenia (SZ) is a prevalent mental disorder characterized by cognitive, emotional, and behavioral changes. Symptoms of SZ include hallucinations, illusions, delusions, lack of motivation, and difficulties in concentration. Diagnosing…

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