English
Related papers

Related papers: Unsupervised Mutual Transformer Learning for Multi…

200 papers

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Milan Aryal , Nasim Yahyasoltani

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Multiple Instance Learning (MIL) methods have become increasingly popular for classifying giga-pixel sized Whole-Slide Images (WSIs) in digital pathology. Most MIL methods operate at a single WSI magnification, by processing all the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Kevin Thandiackal , Boqi Chen , Pushpak Pati , Guillaume Jaume , Drew F. K. Williamson , Maria Gabrani , Orcun Goksel

Introducing interpretability and reasoning into Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) analysis is challenging, given the complexity of gigapixel slides. Traditionally, MIL interpretability is limited to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Saarthak Kapse , Pushpak Pati , Srijan Das , Jingwei Zhang , Chao Chen , Maria Vakalopoulou , Joel Saltz , Dimitris Samaras , Rajarsi R. Gupta , Prateek Prasanna

Whole slide image (WSI) classification requires repetitive zoom-in and out for pathologists, as only small portions of the slide may be relevant to detecting cancer. Due to the lack of patch-level labels, multiple instance learning (MIL) is…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Seongho Keum , Sanghyun Kim , Soojeong Lee , Juho Lee

Mitosis count is an important biomarker for prognosis of various cancers. At present, pathologists typically perform manual counting on a few selected regions of interest in breast whole-slide-images (WSIs) of patient biopsies. This task is…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Saad Ullah Akram , Talha Qaiser , Simon Graham , Juho Kannala , Janne Heikkilä , Nasir Rajpoot

Multiple Instance Learning (MIL) is widely used in analyzing histopathological Whole Slide Images (WSIs). However, existing MIL methods do not explicitly model the data distribution, and instead they only learn a bag-level or instance-level…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Linhao Qu , Xiaoyuan Luo , Shaolei Liu , Manning Wang , Zhijian Song

Despite remarkable efforts been made, the classification of gigapixels whole-slide image (WSI) is severely restrained from either the constrained computing resources for the whole slides, or limited utilizing of the knowledge from different…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Ming Feng , Kele Xu , Nanhui Wu , Weiquan Huang , Yan Bai , Changjian Wang , Huaimin Wang

Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Zhenzhen Wang , Carla Saoud , Sintawat Wangsiricharoen , Aaron W. James , Aleksander S. Popel , Jeremias Sulam

Hyperspectral image (HSI) classification is gaining a lot of momentum in present time because of high inherent spectral information within the images. However, these images suffer from the problem of curse of dimensionality and usually…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Shivam Pande , Nassim Ait Ali Braham , Yi Wang , Conrad M Albrecht , Biplab Banerjee , Xiao Xiang Zhu

Histopathology image analysis is the golden standard of clinical diagnosis for Cancers. In doctors daily routine and computer-aided diagnosis, the Whole Slide Image (WSI) of histopathology tissue is used for analysis. Because of the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Honglin Li , Yunlong Zhang , Chenglu Zhu , Jiatong Cai , Sunyi Zheng , Lin Yang

Traditional image-based survival prediction models rely on discriminative patch labeling which make those methods not scalable to extend to large datasets. Recent studies have shown Multiple Instance Learning (MIL) framework is useful for…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Jiawen Yao , Xinliang Zhu , Jitendra Jonnagaddala , Nicholas Hawkins , Junzhou Huang

Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

In this paper, we develop a new weakly-supervised learning algorithm to learn to segment cancerous regions in histopathology images. Our work is under a multiple instance learning framework (MIL) with a new formulation, deep weak…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Zhipeng Jia , Xingyi Huang , Eric I-Chao Chang , Yan Xu

We present a novel weakly-supervised framework for classifying whole slide images (WSIs). WSIs, due to their gigapixel resolution, are commonly processed by patch-wise classification with patch-level labels. However, patch-level labels…

Computer Vision and Pattern Recognition · Computer Science 2022-03-10 Tiange Xiang , Yang Song , Chaoyi Zhang , Dongnan Liu , Mei Chen , Fan Zhang , Heng Huang , Lauren O'Donnell , Weidong Cai

Whole Slide Images (WSIs) are critical for various clinical applications, including histopathological analysis. However, current deep learning approaches in this field predominantly focus on individual tumor types, limiting model…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Sharon Peled , Yosef E. Maruvka , Moti Freiman

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Multiple Instance Learning (MIL) methods have succeeded remarkably in histopathology whole slide image (WSI) analysis. However, most MIL models only offer attention-based explanations that do not faithfully capture the model's decision…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Susu Sun , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Weakly supervised whole slide image classification is usually formulated as a multiple instance learning (MIL) problem, where each slide is treated as a bag, and the patches cut out of it are treated as instances. Existing methods either…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Linhao Qu , Yingfan Ma , Xiaoyuan Luo , Manning Wang , Zhijian Song