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Large language models (LLMs) are a special class of pretrained language models obtained by scaling model size, pretraining corpus and computation. LLMs, because of their large size and pretraining on large volumes of text data, exhibit…

Computation and Language · Computer Science 2023-10-20 Katikapalli Subramanyam Kalyan

Protein language models learn powerful representations directly from sequences of amino acids. However, they are constrained to generate proteins with only the set of amino acids represented in their vocabulary. In contrast, chemical…

Biomolecules · Quantitative Biology 2023-08-21 Daniel Flam-Shepherd , Kevin Zhu , Alán Aspuru-Guzik

This paper proposes MapGPT which is a novel approach that integrates the capabilities of language models, specifically large language models (LLMs), with spatial data processing techniques. This paper introduces MapGPT, which aims to bridge…

Artificial Intelligence · Computer Science 2023-10-19 Ashley Fernandez , Swaraj Dube

The parallels between protein sequences and natural language in their sequential structures have inspired the application of large language models (LLMs) to protein understanding. Despite the success of LLMs in NLP, their effectiveness in…

Quantitative Methods · Quantitative Biology 2024-07-09 Yiqing Shen , Zan Chen , Michail Mamalakis , Luhan He , Haiyang Xia , Tianbin Li , Yanzhou Su , Junjun He , Yu Guang Wang

In this paper, we lay out a vision for analysing semantic trajectory traces and generating synthetic semantic trajectory data (SSTs) using generative language model. Leveraging the advancements in deep learning, as evident by progress in…

Computation and Language · Computer Science 2023-06-27 Shreya Ghosh , Saptarshi Sengupta , Prasenjit Mitra

Recent advances in Natural Language Processing, and in particular on the construction of very large pre-trained language representation models, is opening up new perspectives on the construction of conversational information seeking (CIS)…

Computation and Language · Computer Science 2022-04-08 Patrizio Bellan , Mauro Dragoni , Chiara Ghidini

Generative protein language models are a natural way to design new proteins with desired functions. However, current models are either difficult to direct to produce a protein from a specific family of interest, or must be trained on a…

Quantitative Methods · Quantitative Biology 2024-01-08 Timothy F. Truong , Tristan Bepler

In this paper, we aimed to provide a review and tutorial for researchers in the field of medical imaging using language models to improve their tasks at hand. We began by providing an overview of the history and concepts of language models,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 Mingzhe Hu , Shaoyan Pan , Yuheng Li , Xiaofeng Yang

The adaptation of Large Language Models like ChatGPT for information retrieval from scientific data, software and publications is offering new opportunities to simplify access to and understanding of science for persons from all levels of…

Instrumentation and Methods for Astrophysics · Physics 2025-01-14 Jutta Schnabel

The recent release of very large language models such as PaLM and GPT-4 has made an unprecedented impact in the popular media and public consciousness, giving rise to a mixture of excitement and fear as to their capabilities and potential…

In recent years, the study of artificial intelligence (AI) has undergone a paradigm shift. This has been propelled by the groundbreaking capabilities of generative models both in supervised and unsupervised learning scenarios. Generative AI…

Machine Learning · Computer Science 2024-05-21 Sandeep Singh Sengar , Affan Bin Hasan , Sanjay Kumar , Fiona Carroll

Language models are powerful tools for molecular design. Currently, the dominant paradigm is to parse molecular graphs into linear string representations that can easily be trained on. This approach has been very successful, however, it is…

Machine Learning · Computer Science 2023-05-11 Daniel Flam-Shepherd , Alán Aspuru-Guzik

Modern Protein Language Models (PLMs) apply transformer-based model architectures from natural language processing to biological sequences, predicting a variety of protein functions and properties. However, protein language has key…

Machine Learning · Computer Science 2026-02-25 Anna Hart , Chi Han , Jeonghwan Kim , Huimin Zhao , Heng Ji

Cutting-edge Artificial Intelligence (AI) techniques keep reshaping our view of the world. For example, Large Language Models (LLMs) based applications such as ChatGPT have shown the capability of generating human-like conversation on…

In recent times, the grandeur of Large Language Models (LLMs) has not only shone in the realm of natural language processing but has also cast its brilliance across a vast array of applications. This remarkable display of LLM capabilities…

Computation and Language · Computer Science 2024-03-22 Hanieh Alipour , Nick Pendar , Kohinoor Roy

In recent times, Transformer-based language models are making quite an impact in the field of natural language processing. As relevant parallels can be drawn between biological sequences and natural languages, the models used in NLP can be…

Computation and Language · Computer Science 2025-12-25 Nimisha Ghosh , Daniele Santoni , Indrajit Saha , Giovanni Felici

Empathetic dialogue is an indispensable part of building harmonious social relationships and contributes to the development of a helpful AI. Previous approaches are mainly based on fine small-scale language models. With the advent of…

Computation and Language · Computer Science 2024-07-29 Yushan Qian , Wei-Nan Zhang , Ting Liu

When we speak, write or listen, we continuously make predictions based on our knowledge of a language's grammar. Remarkably, children acquire this grammatical knowledge within just a few years, enabling them to understand and generalise to…

Computation and Language · Computer Science 2024-11-26 Jaap Jumelet

Transformer architectures contribute to managing long-term dependencies for Natural Language Processing, representing one of the most recent changes in the field. These architectures are the basis of the innovative, cutting-edge Large…

Computation and Language · Computer Science 2024-09-06 Silvia García-Méndez , Francisco de Arriba-Pérez , María del Carmen Somoza-López

Large Language Models (LLMs) have drawn a lot of attention due to their strong performance on a wide range of natural language tasks, since the release of ChatGPT in November 2022. LLMs' ability of general-purpose language understanding and…

Computation and Language · Computer Science 2025-03-25 Shervin Minaee , Tomas Mikolov , Narjes Nikzad , Meysam Chenaghlu , Richard Socher , Xavier Amatriain , Jianfeng Gao
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